Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma (Q36944788)

17 August 2017

Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma (English)

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17 August 2017

retinal ganglion cell

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6

Adriana Di Polo

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17 August 2017

7

H Uri Saragovi

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17 August 2017

ZhiHua Shi

1

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17 August 2017

Marcelo Rudzinski

2

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17 August 2017

Karen Meerovitch

3

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17 August 2017

Frédéric Lebrun-Julien

4

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17 August 2017

Elena Birman

5

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17 August 2017

language of work or name

English

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publication date

13 August 2008

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Journal of Biological Chemistry

17 August 2017

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17 August 2017

283

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17 August 2017

43

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17 August 2017

29156-29165

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describes a project that uses

17 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2570857/fullTextXML

inferred from PubMed Central ID database lookup

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Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

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Comparative binding of biotinylated neurotrophins to alpha(2)-macroglobulin family of proteins: relationship between cytokine-binding and neuro-modulatory activities of the macroglobulins

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Retinal ganglion cells, glaucoma and neuroprotection.

29 September 2017

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Beyond intraocular pressure: neuroprotective strategies for future glaucoma therapy

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Intraocular pressure and the rate of visual field loss in chronic open-angle glaucoma

27 June 2018

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Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors

27 June 2018

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Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension

21 January 2018

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The patterns of retinal ganglion cell death in hypertensive eyes

21 January 2018

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Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma

21 January 2018

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Long-term non-invasive measurement of intraocular pressure in the rat eye.

21 January 2018

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TUNEL-Positive Ganglion Cells in Human Primary Open-angle Glaucoma

21 January 2018

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Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage

21 January 2018

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Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure

21 January 2018

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alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons

21 January 2018

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Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons

21 January 2018

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Elevation of LDL receptor-related protein levels via ligand interactions in Alzheimer disease and in vitro

21 January 2018

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Rate of optic disc cup progression in treated primary open-angle glaucoma

21 January 2018

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Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model.

21 January 2018

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TNF-alpha and TNF-alpha receptor-1 in the retina of normal and glaucomatous eyes

21 January 2018

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Neurotrophic rationale in glaucoma: a TrkA agonist, but not NGF or a p75 antagonist, protects retinal ganglion cells in vivo

4 September 2018

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12 December 2020

Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma

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12 December 2020

Role of alpha2-macroglobulin in regulating amyloid beta-protein neurotoxicity: protective or detrimental factor?

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12 December 2020

Differential gene expression in astrocytes from human normal and glaucomatous optic nerve head analyzed by cDNA microarray

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12 December 2020

Low-density lipoprotein receptor-related protein mediates in PC12 cell cultures the inhibition of nerve growth factor-promoted neurite outgrowth by pregnancy zone protein and alpha2-macroglobulin

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12 December 2020

The onset and evolution of glaucomatous visual field defects

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12 December 2020

Topical timolol administration reduces the incidence of glaucomatous damage in ocular hypertensive individuals. A randomized, double-masked, long-term clinical trial

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12 December 2020

Preliminary studies on the interaction of TNF alpha and IFN gamma with alpha 2-macroglobulin

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12 December 2020

Rat alpha(2)-macroglobulin inhibits NGF-promoted neurite outgrowth, TrK phosphorylation, and gene expression of pheochromocytoma PC12 cells

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12 December 2020

Microarray analysis of the failure of filtering blebs in a rat model of glaucoma filtering surgery

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12 December 2020

Identifiers

DOI

10.1074/JBC.M802365200

1 reference

17 August 2017

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17 August 2017

PubMed publication ID

18701465

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