Catalytically inactive human cathepsin D triggers fibroblast invasive growth (Q36321336)

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7 January 2020

title

Catalytically inactive human cathepsin D triggers fibroblast invasive growth (English)

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7 January 2020

6

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7 January 2020

Peter Coopman

9

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7 January 2020

Gilles Freiss

13

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Emmanuelle Liaudet-Coopman

7 January 2020

15

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7 January 2020

author name string

Valérie Laurent-Matha

1

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7 January 2020

Sharon Maruani-Herrmann

2

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7 January 2020

Christine Prébois

3

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7 January 2020

Mélanie Beaujouin

4

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7 January 2020

Murielle Glondu

5

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7 January 2020

Marie Luz Alvarez-Gonzalez

7

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7 January 2020

Sylvia Blacher

8

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7 January 2020

Stephen Baghdiguian

10

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7 January 2020

Christine Gilles

11

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7 January 2020

Jadranka Loncarek

12

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7 January 2020

Françoise Vignon

14

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7 January 2020

language of work or name

English

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publication date

24 January 2005

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7 January 2020

number of pages

11

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inferred from page(s)

published in

Journal of Cell Biology

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7 January 2020

volume

168

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7 January 2020

issue

3

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7 January 2020

page(s)

489-499

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Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN.

7 January 2020

cites work

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Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.

30 September 2017

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Hepatocyte growth factor secreted by prostate-derived stromal cells stimulates growth of androgen-independent human prostatic carcinoma cells

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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

30 September 2017

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30 September 2017

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Cathepsin D in cancer metastasis: a protease and a ligand

30 September 2017

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Cathepsin-D in primary breast cancer: prognostic evaluation involving 2810 patients

30 September 2017

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In Vivo Evidence That the Stromelysin-3 Metalloproteinase Contributes in a Paracrine Manner to Epithelial Cell Malignancy

30 September 2017

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Relationship between cathepsin-D content and disease-free survival in node-negative breast cancer patients: a meta-analysis.

30 September 2017

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Two crystal structures for cathepsin D: the lysosomal targeting signal and active site

30 September 2017

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30 September 2017

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Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

30 September 2017

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Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells

30 September 2017

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In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Proteolytic Activation of Human Procathepsin D

30 September 2017

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30 September 2017

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30 September 2017

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A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells.

30 September 2017

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29 June 2018

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Control of invasive growth by hepatocyte growth factor (HGF) and related scatter factors

29 June 2018

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29 June 2018

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29 June 2018

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Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

29 June 2018

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Cathepsin D in breast cancer: a tissue marker associated with metastasis

29 June 2018

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Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

29 June 2018

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Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice

22 September 2018

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Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.

22 September 2018

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Fibroblasts capture cathepsin D secreted by breast cancer cells: possible role in the regulation of the invasive process

22 September 2018

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Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.

22 September 2018

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Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

22 September 2018

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Molecular aspects of the endocytic pathway

22 September 2018

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Endocytosis of pro-cathepsin D into breast cancer cells is mostly independent of mannose-6-phosphate receptors.

22 September 2018

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Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal

22 September 2018

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12 December 2020

MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions

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12 December 2020

Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis

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12 December 2020

Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells

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12 December 2020

Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors

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12 December 2020

Identifiers

DOI

10.1083/JCB.200403078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15668295%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

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7 January 2020

PubMed publication ID

15668295

1 reference