Ras and Rho GTPases: a family reunion (Q34073399)

30 July 2017

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title

Ras and Rho GTPases: a family reunion (English)

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30 July 2017

Bar-Sagi D

1

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30 July 2017

Hall A

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

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30 July 2017

volume

103

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30 July 2017

issue

2

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30 July 2017

page(s)

227-238

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Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

A role for Cdc42 in macrophage chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activate NF-kappa B or die?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Motility and invasion are differentially modulated by Rho family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Cooperative interaction of S. pombe proteins required for mating and morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Regulation of phospholipase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Oncogenic Ha-Ras-induced Signaling Activates NF-κB Transcriptional Activity, Which Is Required for Cellular Transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rac "insert region" is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

1 reference

7 January 2021

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

GTPases in antigen receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Integrin signaling and cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Involvement of Ral GTPase in v-Src-induced phospholipase D activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

A Rac1 effector site controlling mitogenesis through superoxide production

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

"Peptide walking" is a novel method for mapping functional domains in proteins. Its application to the Rac1-dependent activation of NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Cell cycle targets of Ras/Raf signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The activation of phosphatidylinositol 3-kinase by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Role of p120 Ras-GAP in directed cell movement

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

RalA interacts directly with the Arf-responsive, PIP2-dependent phospholipase D1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Requirement of NF-κB Activation to Suppress p53-Independent Apoptosis Induced by Oncogenic Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The Actin Cytoskeleton and Lymphocyte Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Activation of Rac and Cdc42 by integrins mediates cell spreading

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

A role for Rho in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Growth factor activation of MAP kinase requires cell adhesion.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Transformation mediated by RhoA requires activity of ROCK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Bidirectional signaling between the cytoskeleton and integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

EPS8 and E3B1 transduce signals from Ras to Rac

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

High-Intensity Raf Signal Causes Cell Cycle Arrest Mediated by p21Cip1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

1 reference

7 January 2021

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The Akt proto-oncogene links Ras to Pak and cell survival signals

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rac-1 regulates nuclear factor of activated T cells (NFAT) C1 nuclear translocation in response to Fcepsilon receptor type 1 stimulation of mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras-stimulated Extracellular Signal-related Kinase 1 and RhoA Activities Coordinate Platelet-derived Growth Factor-induced G1 Progression through the Independent Regulation of Cyclin D1 and p27KIP1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Ras caught in another affair: the exchange factors for Ral.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Rho-stimulated Contractility Contributes to the Fibroblastic Phenotype of Ras-transformed Epithelial Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900115-X

7 January 2021

10.1016/S0092-8674(00)00115-X

Identifiers

DOI

1 reference

release_4d7m3cawvzfsverqcylydyv5y4

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4d7m3cawvzfsverqcylydyv5y4

24 November 2022

mapped directly with Wikidata item

1 reference