Apolipoprotein E is a prime suspect, not just an accomplice, in Alzheimer's disease. (Q35794564)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

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title

Apolipoprotein E is a prime suspect, not just an accomplice, in Alzheimer's disease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Keith A Crutcher

series ordinal

1

1 reference

10 August 2017

publication date

1 January 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Neuroscience

29 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

23

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29 December 2019

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

181-188

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Peripheral nerve regeneration in the apolipoprotein-E-deficient mouse

29 December 2019

cites work

1 reference

12 December 2020

APOE genotype is a major predictor of long-term progression of disability in MS

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12 December 2020

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

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12 December 2020

Expression of apolipoprotein E during nerve degeneration and regeneration

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease

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A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease.

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Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner

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[The examination of apoE phenotypes in diabetic patients with peripheral neuropathy]

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Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

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12 December 2020

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

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12 December 2020

HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy

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12 December 2020

Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis

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12 December 2020

Is Alzheimer's disease an apolipoprotein E amyloidosis?

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12 December 2020

Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond

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12 December 2020

Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

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12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

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12 December 2020

Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases.

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12 December 2020

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls

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12 December 2020

Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis

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12 December 2020

A "protease activation cascade" in the pathogenesis of Alzheimer's disease.

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12 December 2020

Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

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12 December 2020

Neurite degeneration elicited by apolipoprotein E peptides

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12 December 2020

Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation

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12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

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12 December 2020

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

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12 December 2020

Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis

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12 December 2020

Beta-VLDL protects against A beta(1-42) and apoE toxicity in human SH-SY5Y neuroblastoma cells

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12 December 2020

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

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12 December 2020

ApoE immunoreactivity and microglial cells in Alzheimer's disease brain.

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12 December 2020

Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study

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12 December 2020

A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity

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12 December 2020

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

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12 December 2020

Conversion of brain apolipoprotein E to an insoluble form in a mouse model of Alzheimer disease

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12 December 2020

APOE: a potential marker of disease progression in ALS

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12 December 2020

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

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12 December 2020

Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein

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12 December 2020

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

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12 December 2020

Synaptic loss is accompanied by an increase in synaptic area in the dentate gyrus of aged human apolipoprotein E4 transgenic mice

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12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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12 December 2020

Evaluation of the interactions of common genetic mutations in stroke subtypes

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12 December 2020

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

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12 December 2020

Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study

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12 December 2020

The role of apolipoprotein E in the nervous system.

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12 December 2020

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

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12 December 2020

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

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12 December 2020

Apolipoprotein E polymorphism and acute ischemic stroke: a diffusion- and perfusion-weighted magnetic resonance imaging study

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12 December 2020

Nerve regeneration occurs in the absence of apolipoprotein E in mice

1 reference

12 December 2020

Isoform-Specific Effect of Apolipoprotein E on Cell Survival and β-Amyloid-Induced Toxicity in Rat Hippocampal Pyramidal Neuronal Cultures

1 reference

12 December 2020

Apolipoprotein E genotype, coagulation, and survival following acute stroke

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12 December 2020

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

1 reference

12 December 2020

Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis

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12 December 2020

A test of the cytosolic apolipoprotein E hypothesis fails to detect the escape of apolipoprotein E from the endocytic pathway into the cytosol and shows that direct expression of apolipoprotein E in the cytosol is cytotoxic.

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12 December 2020

Risk for Alzheimer's disease correlates with transcriptional activity of the APOE gene.

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12 December 2020

Role of Lipoproteins in the Delivery of Lipids to Axons during Axonal Regeneration

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12 December 2020

The -491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer's disease.

1 reference

12 December 2020

Neurotoxic effects of apolipoprotein E4 are mediated via dysregulation of calcium homeostasis

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12 December 2020

Apolipoprotein E4 stimulates cAMP response element-binding protein transcriptional activity through the extracellular signal-regulated kinase pathway

1 reference

12 December 2020

Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease

1 reference

12 December 2020

Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice

1 reference

12 December 2020

Apolipoprotein E ∈4 Associated With Chronic Traumatic Brain Injury in Boxing

1 reference

12 December 2020

APOE genotype influences acquisition and recall following traumatic brain injury

1 reference

12 December 2020

Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury

1 reference

12 December 2020

Apolipoprotein E gene polymorphism in cerebrovascular disease: a case-control study

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization

1 reference

12 December 2020

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation

1 reference

12 December 2020

Apoliprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate

1 reference

12 December 2020

Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: a possible role for apolipoprotein E in Alzheimer's disease

1 reference

12 December 2020

Non-familial Alzheimer's disease is mainly due to genetic factors.

1 reference

12 December 2020

Apolipoprotein E and neuromuscular disease: a critical review of the literature

1 reference

12 December 2020

APOE genotype is a risk factor for neuropathy severity in diabetic patients

1 reference

12 December 2020

Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.

1 reference

12 December 2020

APOE genotype is a major predictor of long-term progression of disability in MS

1 reference

12 December 2020

Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

1 reference

12 December 2020

Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene

1 reference

12 December 2020

Age-dependent association of apolipoprotein E genotypes with stroke subtypes in a Japanese rural population

1 reference

12 December 2020

Secretases as targets for the treatment of Alzheimer's disease

1 reference

12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

12 December 2020

Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains

1 reference

12 December 2020

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

12 December 2020

Identifiers

DOI

10.1385/JMN:23:3:181

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15181246%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

1035603495

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Fatcat ID

release_danildkgv5g7vbtpgamukyqc3e

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Fatcat

https://api.fatcat.wiki/v0/release/danildkgv5g7vbtpgamukyqc3e

24 November 2022

mapped directly with Wikidata item

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