Genetically engineered mouse models of mammary intraepithelial neoplasia (Q35671166)

9 August 2017

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title

Genetically engineered mouse models of mammary intraepithelial neoplasia (English)

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9 August 2017

Cardiff RD

1

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9 August 2017

Moghanaki D

series ordinal

2

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9 August 2017

Jensen RA

series ordinal

3

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9 August 2017

publication date

1 October 2000

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Journal of Mammary Gland Biology and Neoplasia

9 August 2017

published in

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9 August 2017

volume

5

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9 August 2017

issue

4

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9 August 2017

page(s)

421-437

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Role of endocrine, autocrine, and paracrine interactions in the development of mammary hyperplasia in Wnt-1 transgenic mice

9 August 2017

cites work

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12 December 2020

p53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice: suppression of apoptosis during the transition from preneoplasia to carcinoma

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12 December 2020

Ectopic vasopressin expression in MMTV-Wnt-1 transgenic mice modifies mammary tumor differentiation and pathology

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12 December 2020

Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression

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12 December 2020

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

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12 December 2020

Overexpression of cyclin A in the mammary glands of transgenic mice results in the induction of nuclear abnormalities and increased apoptosis

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12 December 2020

Preneoplastic Lesions in the Human Breast

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12 December 2020

Transgenic models of breast cancer metastasis.

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12 December 2020

A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.

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12 December 2020

Protein tyrosine phosphatase epsilon increases the risk of mammary hyperplasia and mammary tumors in transgenic mice.

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12 December 2020

Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

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12 December 2020

The preneoplastic state in mouse mammary tumorigenesis

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12 December 2020

Tumorigenesis and male sterility in transgenic mice expressing a MMTV/N-ras oncogene

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12 December 2020

Persistent and atypical lobules in the human breast may be precancerous

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12 December 2020

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

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12 December 2020

Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression

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12 December 2020

The int-2 gene product acts as an epithelial growth factor in transgenic mice

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12 December 2020

Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells.

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12 December 2020

Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice

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12 December 2020

Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice

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12 December 2020

Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis

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12 December 2020

Risk factors for breast cancer in women with proliferative breast disease

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12 December 2020

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

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12 December 2020

A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice.

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12 December 2020

Development of human breast cancer.

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12 December 2020

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

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12 December 2020

C-myc protein distribution - mammary adenocarcinomas of mtv/myc transgenic mice

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12 December 2020

FVB/N: an inbred mouse strain preferable for transgenic analyses

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12 December 2020

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

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12 December 2020

MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia

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12 December 2020

Development of hyperplasias, preneoplasias, and mammary tumors in MMTV-c-erbB-2 and MMTV-TGFalpha transgenic rats

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12 December 2020

The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma

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12 December 2020

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

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12 December 2020

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

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12 December 2020

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

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12 December 2020

Transgenic oncogene mice. Tumor phenotype predicts genotype

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12 December 2020

Mammary tumorigenesis and metastasis in transgenic mice.

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12 December 2020

Breast cancer risk of lobular-based hyperplasia after biopsy: "ductal" pattern lesions

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12 December 2020

An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions

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12 December 2020

Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice

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12 December 2020

Comparative pathology of mammary tumorigenesis in transgenic mice

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12 December 2020

An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice

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12 December 2020

Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues

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12 December 2020

Epidermal growth factor-like growth factors. I. Breast malignancies and other epithelial proliferations in transgenic mice

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12 December 2020

Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis.

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12 December 2020

The prevalence of the precancerous lesions in breasts contralateral to clinical cancer. A morphological comparison with breasts containing a benign lump

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12 December 2020

Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer

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12 December 2020

Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice

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12 December 2020

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

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12 December 2020

Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice

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12 December 2020

Preneoplastic mammary tumor markers: Cripto and Amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice

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12 December 2020

Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy

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12 December 2020

The comparative pathology of human and mouse mammary glands

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12 December 2020

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

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12 December 2020

Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability

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12 December 2020

Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene

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12 December 2020

The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis

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12 December 2020

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

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12 December 2020

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors

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12 December 2020

Ductal carcinoma in situ: introduction of the concept of ductal intraepithelial neoplasia

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12 December 2020

Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription

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12 December 2020

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis

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12 December 2020

Breast Cancer Protein PS2 Synthesis in Mammary Gland of Transgenic Mice and Secretion into Milk

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12 December 2020

Spontaneous lesions in aging FVB/N mice

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12 December 2020

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

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12 December 2020

Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities

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12 December 2020

Transgenic mouse models of breast cancer

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12 December 2020

Preneoplasia in mammary tumorigenesis.

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12 December 2020

Preneoplastic lesions of the human mammary gland transplanted into the nude athymic mouse

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12 December 2020

Oncogenic activation of Neu/ErbB-2 in a transgenic mouse model for breast cancer

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12 December 2020

Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations

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12 December 2020

Biology of breast preneoplasia

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12 December 2020

Breast cancer formation in transgenic animals induced by the whey acidic protein SV40 T antigen (WAP-SV-T) hybrid gene

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12 December 2020

Nonuniform expression of a mouse mammary tumor virus-driven int-2/Fgf-3 transgene in pregnancy-responsive breast tumors

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12 December 2020

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

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12 December 2020

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

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12 December 2020

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

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12 December 2020

A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland

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12 December 2020

Protoneoplasia: The Molecular Biology of Murine Mammary Hyperplasia

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12 December 2020

Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage

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12 December 2020

Transgenic mouse models of mammary tumorigenesis

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12 December 2020

Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis

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12 December 2020

Differential expression of the neu transgene in murine mammary tissues

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12 December 2020

The mammary gland: a unique organ for the study of development and tumorigenesis

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12 December 2020

Active signaling by Neu in transgenic mice

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12 December 2020

Insertion mutation of the int-1 and int-2 loci by mouse mammary tumor virus in premalignant and malignant neoplasms from the GR mouse strain

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12 December 2020

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

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12 December 2020

On the origin and progression of ductal carcinoma in the human breast

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12 December 2020

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

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12 December 2020

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

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12 December 2020

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

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12 December 2020

NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice

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12 December 2020

Development of mammary and cutaneous gland tumors in transgenic mice carrying the RET/PTC1 oncogene.

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12 December 2020

Correlative studies of the histological and radiographic appearance of the breast parenchyma

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12 December 2020

Effects of melatonin on mammary gland lesions in transgenic mice overexpressing N-ras proto-oncogene

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12 December 2020

Subgross pathology of the human breast: method and initial observations

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12 December 2020

Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

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12 December 2020

Apocrine cystic metaplasia: subgross pathology and prevalence in cancer-associated versus random autopsy breasts

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12 December 2020

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

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12 December 2020

Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.

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12 December 2020

Premalignant and malignant disease of the breast: the roles of the pathologist

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12 December 2020

A Hypothesis of the Origin of Human Breast Cancer from the Terminal Ductal Lobular Unit

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12 December 2020

The biology of mammary transgenes: five rules

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12 December 2020

Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein

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12 December 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

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12 December 2020

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

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12 December 2020

A comparison of the results of long-term follow-up for atypical intraductal hyperplasia and intraductal hyperplasia of the breast

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12 December 2020

Analysis of mammary carcinoma onset and progression in HER-2/neu oncogene transgenic mice reveals a lobular origin

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12 December 2020

Int-2, an autocrine and/or ultra-short-range effector in transgenic mammary tissue transplants.

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12 December 2020

Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice

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12 December 2020

Activated neu induces rapid tumor progression

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12 December 2020

Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice

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12 December 2020

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

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12 December 2020

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

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12 December 2020

Keratinocyte growth factor induces mammary and prostatic hyperplasia and mammary adenocarcinoma in transgenic mice.

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12 December 2020

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

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12 December 2020

Identifiers

DOI

10.1023/A:1009534129331

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Dimensions Publication ID

9 August 2017

1032331768

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