Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models. (Q35287351)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446664%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models (English)

1 reference

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23 February 2020

1 reference

1 reference

1 reference

1

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23 February 2020

Michael Bradaric

8

1 reference

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23 February 2020

Iris L Romero

10

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23 February 2020

author name string

Lacey M Litchfield

2

1 reference

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23 February 2020

Anirban K Mitra

3

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23 February 2020

Kristin M Nieman

4

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23 February 2020

Abir Mukherjee

5

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23 February 2020

Yilin Zhang

6

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23 February 2020

Alyssa Johnson

7

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23 February 2020

WooSeok Lee

9

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23 February 2020

language of work or name

English

0 references

publication date

19 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446664%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Obstetrics and Gynecology

23 February 2020

published in

1 reference

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23 February 2020

volume

212

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23 February 2020

issue

4

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23 February 2020

page(s)

479.e1-479.e10

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Clinical investigation of receptor and non-receptor tyrosine kinase inhibitors for the treatment of epithelial ovarian cancer

23 February 2020

cites work

1 reference

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Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells

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Metformin inhibits the growth of human pancreatic cancer xenografts

12 July 2018

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Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

12 July 2018

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Metformin intake is associated with better survival in ovarian cancer: a case-control study

12 July 2018

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Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

12 July 2018

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Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial

12 July 2018

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Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity.

12 July 2018

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Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells.

12 July 2018

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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

12 July 2018

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The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis

12 July 2018

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Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo.

12 July 2018

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Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis

12 July 2018

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Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents

12 July 2018

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Metformin Prevents Tobacco Carcinogen–Induced Lung Tumorigenesis

12 July 2018

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12 July 2018

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Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena

12 July 2018

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Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acid-binding protein 4.

12 July 2018

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An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis

12 July 2018

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Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16

12 July 2018

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Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

12 July 2018

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Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.

12 July 2018

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New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes

12 July 2018

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Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

12 July 2018

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12 July 2018

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Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target

12 July 2018

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12 July 2018

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The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

12 July 2018

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12 July 2018

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12 July 2018

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer.

12 July 2018

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Metformin and reduced risk of cancer in diabetic patients

12 July 2018

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Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study

12 July 2018

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12 July 2018

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The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c.

12 July 2018

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Prognostic role of the recepteur d'origine nantais (RON) expression in ovarian cancer patients.

26 September 2018

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Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

26 September 2018

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Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

26 September 2018

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Issues in experimental design and endpoint analysis in the study of experimental cytotoxic agents in vivo in breast cancer and other models.

26 September 2018

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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25446664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The impact of diabetes on survival in women with ovarian cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25446664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.AJOG.2014.10.026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446664%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446664%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25446664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25446664%20AND%20SRC:MED&resulttype=core&format=json