AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy (Q29618101)

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3 January 2020

review article

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title

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy (English)

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1

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author name string

Hardie DG

series ordinal

1

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language of work or name

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publication date

1 October 2007

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Nature Reviews Molecular Cell Biology

3 January 2020

published in

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volume

8

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issue

10

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page(s)

774-785

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A yeast gene that is essential for release from glucose repression encodes a protein kinase

3 January 2020

cites work

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

31 March 2020

1 reference

Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome

31 March 2020

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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

31 March 2020

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Role of AMP-activated protein kinase in mechanism of metformin action

31 March 2020

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The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

31 March 2020

1 reference

Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states

31 March 2020

1 reference

Resveratrol improves health and survival of mice on a high-calorie diet

31 March 2020

1 reference

Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway

31 March 2020

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AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

31 March 2020

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AMP-activated protein kinase as a drug target.

31 March 2020

1 reference

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

31 March 2020

1 reference

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

31 March 2020

1 reference

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

31 March 2020

1 reference

An antibody VH domain with a lox-Cre site integrated into its coding region: bacterial recombination within a single polypeptide chain

31 March 2020

1 reference

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

31 March 2020

1 reference

5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

31 March 2020

1 reference

Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice

31 March 2020

1 reference

Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio

31 March 2020

1 reference

Yeast Pak1 Kinase Associates with and Activates Snf1

31 March 2020

1 reference

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase

31 March 2020

1 reference

Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

31 March 2020

1 reference

Functional domains of the alpha1 catalytic subunit of the AMP-activated protein kinase

31 March 2020

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Conserved alpha-helix acts as autoinhibitory sequence in AMP-activated protein kinase alpha subunits.

31 March 2020

1 reference

The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation

31 March 2020

1 reference

The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex

31 March 2020

1 reference

A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.

31 March 2020

1 reference

AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270)

31 March 2020

1 reference

A conserved sequence immediately N-terminal to the Bateman domains in AMP-activated protein kinase gamma subunits is required for the interaction with the beta subunits.

31 March 2020

1 reference

A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits

31 March 2020

1 reference

AMPK beta subunit targets metabolic stress sensing to glycogen

31 March 2020

1 reference

Structural basis for glycogen recognition by AMP-activated protein kinase

31 March 2020

1 reference

Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity

31 March 2020

1 reference

The structure of a domain common to archaebacteria and the homocystinuria disease protein

31 March 2020

1 reference

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

31 March 2020

1 reference

Active site-directed protein regulation

31 March 2020

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Regulation of AMP-activated protein kinase by a pseudosubstrate sequence on the gamma subunit

31 March 2020

1 reference

Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.

31 March 2020

1 reference

Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP-activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency

31 March 2020

1 reference

Fatal infantile cardiac glycogenosis with phosphorylase kinase deficiency and a mutation in the gamma2-subunit of AMP-activated protein kinase

31 March 2020

1 reference

AMP-activated protein kinase in the heart: role during health and disease

31 March 2020

1 reference

Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.

31 March 2020

1 reference

Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome.

31 March 2020

1 reference

Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site

31 March 2020

1 reference

Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP

31 March 2020

1 reference

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage

31 March 2020

1 reference

The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.

31 March 2020

1 reference

A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle

31 March 2020

1 reference

Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation

31 March 2020

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Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

31 March 2020

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Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex

31 March 2020

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

31 March 2020

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

31 March 2020

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The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

31 March 2020

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

31 March 2020

1 reference

Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

31 March 2020

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LKB1-dependent signaling pathways

31 March 2020

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

31 March 2020

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Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

31 March 2020

1 reference

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta

31 March 2020

1 reference

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

31 March 2020

1 reference

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle

31 March 2020

1 reference

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

31 March 2020

1 reference

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle

31 March 2020

1 reference

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

31 March 2020

1 reference

The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1

31 March 2020

1 reference

The Snf1 kinase controls glucose repression in yeast by modulating interactions between the Mig1 repressor and the Cyc8-Tup1 co-repressor

31 March 2020

1 reference

The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae

31 March 2020

1 reference

Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle

31 March 2020

1 reference

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

31 March 2020

1 reference

Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line

31 March 2020

1 reference

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

31 March 2020

1 reference

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

31 March 2020

1 reference

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

31 March 2020

1 reference

AMP-activated kinase regulates cytoplasmic HuR.

31 March 2020

1 reference

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function

31 March 2020

1 reference

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

31 March 2020

1 reference

TSC2 mediates cellular energy response to control cell growth and survival

31 March 2020

1 reference

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

31 March 2020

1 reference

Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p

31 March 2020

1 reference

AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

31 March 2020

1 reference

A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity

31 March 2020

1 reference

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

31 March 2020

1 reference

AMP-activated protein kinase regulates the assembly of epithelial tight junctions

31 March 2020

1 reference

Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase

31 March 2020

1 reference

Energy-dependent regulation of cell structure by AMP-activated protein kinase

31 March 2020

1 reference

SNF1/AMPK/SnRK1 kinases, global regulators at the heart of energy control?

31 March 2020

1 reference

31 March 2020

1 reference

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

31 March 2020

1 reference

Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling

31 March 2020

1 reference

A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion

31 March 2020

1 reference

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31 March 2020

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3 January 2020

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