Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus (Q34460329)

2 August 2017

title

Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus (English)

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2 August 2017

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Hongyan Liu

1

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2 August 2017

Thu Le Trinh

2

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2 August 2017

Huijia Dong

3

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2 August 2017

Robertson Keith

4

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2 August 2017

David Nelson

5

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2 August 2017

Chen Liu

6

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2 August 2017

language of work or name

English

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publication date

22 October 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

10

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2 August 2017

page(s)

e46631

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

22 October 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion

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ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.

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Mechanisms of disease: The role of hepcidin in iron homeostasis--implications for hemochromatosis and other disorders

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Global epidemiology of hepatitis C virus infection

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

6 July 2018

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STAT3 induces anti-hepatitis C viral activity in liver cells

6 July 2018

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6 July 2018

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Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

6 July 2018

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Activation of the interferon system by short-interfering RNAs

6 July 2018

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Interleukin-1 Inhibits Hepatitis C Virus Subgenomic RNA Replication by Activation of Extracellular Regulated Kinase Pathway

6 July 2018

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Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation

6 July 2018

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Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

6 July 2018

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6 July 2018

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Hepatitis C infection in liver transplantation

6 July 2018

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6 July 2018

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Hepatitis C virus infection

6 July 2018

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

6 July 2018

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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

STAT3 complements defects in an interferon-resistant cell line: Evidence for an essential role for STAT3 in interferon signaling and biological activities

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Iron-induced tissue damage and cancer: the role of reactive oxygen species-free radicals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Effect of free iron on collagen synthesis, cell proliferation and MMP-2 expression in rat hepatic stellate cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Iron activates NF-kappaB in Kupffer cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

Purification and partial characterisation of recombinant human hepcidin

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478283

A novel monoclonal antibody immunoassay for the detection of human serum hepcidin

27 October 2018

1 reference

12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

12 December 2020

Hepcidin mRNA level as a parameter of disease progression in chronic hepatitis C and hepatocellular carcinoma

1 reference

12 December 2020

Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0046631

Identifiers

DOI

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2 August 2017

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2 August 2017

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