Linking neurodevelopmental and synaptic theories of mental illness through DISC1 (Q34233683)

31 July 2017

title

Linking neurodevelopmental and synaptic theories of mental illness through DISC1 (English)

1 reference

31 July 2017

Nicholas J Brandon

1

1 reference

31 July 2017

Akira Sawa

series ordinal

2

1 reference

31 July 2017

language of work or name

English

0 references

publication date

18 November 2011

1 reference

Nature Reviews Neuroscience

31 July 2017

published in

1 reference

31 July 2017

volume

12

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31 July 2017

issue

12

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31 July 2017

page(s)

707-722

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Regulation of the cytoskeleton by Disrupted-in-Schizophrenia 1 (DISC1)

31 July 2017

cites work

1 reference

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Convergence of Two Independent Mental Disease Genes on the Protein Level: Recruitment of Dysbindin to Cell-Invasive Disrupted-In-Schizophrenia 1 Aggresomes

6 July 2018

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NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1)

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Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition

6 July 2018

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Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia

6 July 2018

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Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes

6 July 2018

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DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

6 July 2018

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Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.

6 July 2018

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Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling

6 July 2018

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6 July 2018

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Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation

6 July 2018

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6 July 2018

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6 July 2018

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The Data of Diagnosis: New Approaches to Psychiatric Classification

6 July 2018

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DISC1 in schizophrenia: genetic mouse models and human genomic imaging

6 July 2018

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Activity-Dependent Ubiquitination of GluA1 Mediates a Distinct AMPA Receptor Endocytosis and Sorting Pathway

6 July 2018

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Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology

6 July 2018

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6 July 2018

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6 July 2018

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MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function

6 July 2018

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Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility

6 July 2018

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CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration

6 July 2018

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Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses

6 July 2018

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Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin

6 July 2018

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Identification of high risk DISC1 protein structural variants in patients with bipolar spectrum disorder

6 July 2018

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The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.

6 July 2018

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6 July 2018

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The Hippocampal Formation in Schizophrenia

6 July 2018

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Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi

6 July 2018

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Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.

6 July 2018

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Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development

6 July 2018

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Common functional polymorphisms of DISC1 and cortical maturation in typically developing children and adolescents

6 July 2018

1 reference

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Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

6 July 2018

1 reference

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Ubiquitination in postsynaptic function and plasticity

6 July 2018

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Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Rodent models in depression research: classical strategies and new directions.

6 July 2018

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The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain

6 July 2018

1 reference

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Insoluble DISC1-Boymaw fusion proteins generated by DISC1 translocation

6 July 2018

1 reference

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Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

6 July 2018

1 reference

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Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits

6 July 2018

1 reference

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Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era.

6 July 2018

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Adolescent maturation of cortical dopamine

6 July 2018

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

6 July 2018

1 reference

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Structural dynamics of dendritic spines in memory and cognition

6 July 2018

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Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

6 July 2018

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Control of mitochondrial transport and localization in neurons.

6 July 2018

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The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis

6 July 2018

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AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis

6 July 2018

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Copy-number variants in neurodevelopmental disorders: promises and challenges

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms

6 July 2018

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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

6 July 2018

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Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

6 July 2018

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Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

6 July 2018

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Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

6 July 2018

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Meta-analytic evidence for familial coaggregation of schizophrenia and bipolar disorder.

6 July 2018

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

6 July 2018

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Common variants on chromosome 6p22.1 are associated with schizophrenia

6 July 2018

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Common variants conferring risk of schizophrenia

6 July 2018

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Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation

6 July 2018

1 reference

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Disc1 regulates granule cell migration in the developing hippocampus

6 July 2018

1 reference

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The effect of amygdala kindling on hippocampal neurogenesis coincides with decreased reelin and DISC1 expression in the adult dentate gyrus

6 July 2018

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Schizophrenia genetics: new insights from new approaches

6 July 2018

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Physiological functions of the HECT family of ubiquitin ligases

6 July 2018

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Modeling cognitive endophenotypes of schizophrenia in mice

6 July 2018

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

6 July 2018

1 reference

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Association of variants in DISC1 with psychosis-related traits in a large population cohort

6 July 2018

1 reference

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Psychosocial treatments to promote functional recovery in schizophrenia

6 July 2018

1 reference

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A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.

6 July 2018

1 reference

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Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses

6 July 2018

1 reference

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Comparative risk for harms of second-generation antidepressants : a systematic review and meta-analysis.

6 July 2018

1 reference

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Convergent CaMK and RacGEF signals control dendritic structure and function.

6 July 2018

1 reference

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Delivery of AMPA receptors to perisynaptic sites precedes the full expression of long-term potentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Identification of loci associated with schizophrenia by genome-wide association and follow-up

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The dystrobrevin-binding protein 1 gene: features and networks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Dendritic spine dynamics--a key role for kalirin-7.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted-in-Schizophrenia-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease

6 July 2018

1 reference

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Does disrupted-in-schizophrenia (DISC1) generate fusion transcripts?

6 July 2018

1 reference

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Antipsychotic safety and efficacy concerns

6 July 2018

1 reference

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DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia

6 July 2018

1 reference

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How has DISC1 enabled drug discovery?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Dissecting DISC1 function through protein-protein interactions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The DISC locus in psychiatric illness

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Cognitive neuroscience-based approaches to measuring and improving treatment effects on cognition in schizophrenia: the CNTRICS initiative

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The genetic deconstruction of psychosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The cell biology of synaptic plasticity: AMPA receptor trafficking

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The centrosome in neuronal development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The postsynaptic architecture of excitatory synapses: a more quantitative view

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Fasciculation and elongation protein zeta-1 (FEZ1) participates in the polarization of hippocampal neuron by controlling the mitochondrial motility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted in schizophrenia 1: building brains and memories

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The NIMH-MATRICS consensus statement on negative symptoms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Molecular mechanisms of dendritic spine morphogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Theta rhythms coordinate hippocampal-prefrontal interactions in a spatial memory task

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Strategy for investigating interactions between measured genes and measured environments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Cortical inhibitory neurons and schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 localizes to the centrosome by binding to kendrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Yeast two-hybrid screens implicate DISC1 in brain development and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Evolutionary constraints on the Disrupted in Schizophrenia locus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Obstetric complications and schizophrenia: historical and meta-analytic review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The Ste20 group kinases as regulators of MAP kinase cascades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Postsynaptic organization and regulation of excitatory synapses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to grave

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Disruption of two novel genes by a translocation co-segregating with schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Schizophrenia: genes and environment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Functional and Anatomical Aspects of Prefrontal Pathology in Schizophrenia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Association within a family of a balanced autosomal translocation with major mental illness

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Genomewide Linkage Scan in Schizoaffective Disorder

6 July 2018

1 reference

Association of DISC1 with autism and Asperger syndrome

21 January 2018

1 reference

Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling

21 January 2018

1 reference

Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia

21 January 2018

1 reference

Association of white matter integrity with genetic variation in an exonic DISC1 SNP

21 January 2018

1 reference

Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory

21 January 2018

1 reference

A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia

21 January 2018

1 reference

Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function.

21 January 2018

1 reference

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia

21 January 2018

1 reference

Additive effect of NRG1 and DISC1 genes on lateral ventricle enlargement in first episode schizophrenia.

21 January 2018

1 reference

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

21 January 2018

1 reference

Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development

21 January 2018

1 reference

Disruption of GW bodies impairs mammalian RNA interference

21 January 2018

1 reference

DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release

21 January 2018

1 reference

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

21 January 2018

1 reference

Disc1 point mutations in mice affect development of the cerebral cortex

21 January 2018

1 reference

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

21 January 2018

1 reference

Disrupted-in-Schizophrenia-1 (Disc1) is necessary for migration of the pyramidal neurons during mouse hippocampal development

21 January 2018

1 reference

Behavioral phenotypes of Disc1 missense mutations in mice

21 January 2018

1 reference

Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia.

21 January 2018

1 reference

Proteomic analysis of in vivo phosphorylated synaptic proteins.

21 January 2018

1 reference

The ubiquitin E3 ligase Nedd4-1 controls neurite development.

21 January 2018

1 reference

Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia

21 January 2018

1 reference

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia

21 January 2018

1 reference

Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia

21 January 2018

1 reference

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain

21 January 2018

1 reference

Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.

21 January 2018

1 reference

Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons.

21 January 2018

1 reference

Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth

21 January 2018

1 reference

Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus

21 January 2018

1 reference

Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation

21 January 2018

1 reference

Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3954824

Impact of substance use disorder on ADHD and its treatment.

28 October 2018

1 reference

31 March 2020

1 reference

Genetics. Two genes link two distinct psychoses

31 March 2020

1 reference

Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning

31 March 2020

1 reference

Co-ordinated action of DISC1, PDE4B and GSK3β in modulation of cAMP signalling

31 March 2020

1 reference

Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN3120

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference