Understanding the role of DISC1 in psychiatric disease and during normal development (Q28261398)

title

Understanding the role of DISC1 in psychiatric disease and during normal development (English)

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author

Nicholas J Brandon

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

Hazel Sive

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

author name string

J Kirsty Millar

2

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15 May 2020

Carsten Korth

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

Karun K Singh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

Akira Sawa

6

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15 May 2020

language of work or name

English

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publication date

14 October 2009

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published in

Journal of Neuroscience

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15 May 2020

volume

29

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15 May 2020

issue

41

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15 May 2020

page(s)

12768-12775

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TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

15 May 2020

cites work

1 reference

12 December 2020

Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia

1 reference

12 December 2020

Disruption of two novel genes by a translocation co-segregating with schizophrenia

1 reference

12 December 2020

Shattuck lecture--neurodegenerative diseases and prions

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12 December 2020

Protein-protein interactions, cytoskeletal regulation and neuronal migration

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12 December 2020

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

1 reference

12 December 2020

Toxic proteins in neurodegenerative disease

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12 December 2020

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

1 reference

12 December 2020

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

1 reference

12 December 2020

The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression

1 reference

12 December 2020

Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease

1 reference

12 December 2020

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

1 reference

12 December 2020

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

1 reference

12 December 2020

The centrosome in human genetic disease

1 reference

12 December 2020

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

1 reference

12 December 2020

Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.

1 reference

12 December 2020

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

1 reference

12 December 2020

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

1 reference

12 December 2020

Molecular mechanisms of dendritic spine morphogenesis

1 reference

12 December 2020

Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia.

1 reference

12 December 2020

DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex

1 reference

12 December 2020

Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia

1 reference

12 December 2020

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

1 reference

12 December 2020

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

1 reference

12 December 2020

Role of actin cytoskeleton in dendritic spine morphogenesis.

1 reference

12 December 2020

Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

1 reference

12 December 2020

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

1 reference

12 December 2020

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia

1 reference

12 December 2020

The DISC locus in psychiatric illness

1 reference

12 December 2020

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

1 reference

12 December 2020

Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines

1 reference

12 December 2020

How has DISC1 enabled drug discovery?

1 reference

12 December 2020

Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia

1 reference

12 December 2020

Does disrupted-in-schizophrenia (DISC1) generate fusion transcripts?

1 reference

12 December 2020

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease

1 reference

12 December 2020

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

1 reference

12 December 2020

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

1 reference

12 December 2020

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding

1 reference

12 December 2020

Dendritic spine dynamics--a key role for kalirin-7.

1 reference

12 December 2020

Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses

1 reference

12 December 2020

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.

1 reference

12 December 2020

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

1 reference

12 December 2020

DISC1-kendrin interaction is involved in centrosomal microtubule network formation

1 reference

12 December 2020

A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype

1 reference

12 December 2020

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

1 reference

12 December 2020

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

1 reference

12 December 2020

Modeling cognitive endophenotypes of schizophrenia in mice

1 reference

12 December 2020

Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation

1 reference

12 December 2020

Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C

1 reference

12 December 2020

Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

1 reference

12 December 2020

Association within a family of a balanced autosomal translocation with major mental illness

1 reference

12 December 2020

10.1523/JNEUROSCI.3355-09.2009

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

2032153

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

2032153

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665304&resulttype=core&format=json

15 May 2020

PubMed publication ID

19828788

2 references

Consolidated OpenCitations Corpus – April 2017

2032153