HIV drug resistance and viral fitness. (Q34050677)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11013760%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

review article

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title

HIV drug resistance and viral fitness (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11013760%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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3

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31 October 2019

author name string

Clavel F

series ordinal

1

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31 October 2019

Race E

series ordinal

2

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31 October 2019

publication date

1 January 2000

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31 October 2019

published in

Advances in Pharmacology

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31 October 2019

volume

49

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31 October 2019

page(s)

41-66

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The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase

31 October 2019

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Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

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The HIV-1 protease as a therapeutic target for AIDS

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HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy

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RNA virus mutations and fitness for survival

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Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors

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Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor

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The not-so-great escape

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pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo

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7 January 2021

Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

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7 January 2021

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

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7 January 2021

Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215.

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Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

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Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure

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A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

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Relative replicative fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro

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7 January 2021

Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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7 January 2021

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART)

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7 January 2021

Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency

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7 January 2021

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

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Impaired infectivity of HIV-1 after a single point mutation in the POL gene to escape the effect of a protease inhibitor in vitro

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

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A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.

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Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro

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Effect of point mutations on the kinetics and the inhibition of human immunodeficiency virus type 1 protease: relationship to drug resistance

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7 January 2021

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Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations

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7 January 2021

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

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7 January 2021

Lamivudine‐Resistant Human Immunodeficiency Virus Type 1 Variants (184V) Require Multiple Amino Acid Changes to Become Co‐Resistant to Zidovudine In Vivo

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7 January 2021

Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations

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7 January 2021

Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease

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7 January 2021

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor

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7 January 2021

Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.

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7 January 2021

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

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7 January 2021

Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease

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7 January 2021

The frequency of resistant mutant virus before antiviral therapy

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7 January 2021

Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate

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7 January 2021

The accuracy of reverse transcriptase from HIV-1.

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7 January 2021

Human immunodeficiency virus type 1 protease inhibitors: evaluation of resistance engendered by amino acid substitutions in the enzyme's substrate binding site

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7 January 2021

Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1.

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7 January 2021

Impaired fitness of foscarnet-resistant strains of human immunodeficiency virus type 1.

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7 January 2021

Viral dynamics in human immunodeficiency virus type 1 infection

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Limited sequence diversity of the HIV type 1 protease gene from clinical isolates and in vitro susceptibility to HIV protease inhibitors

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A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors

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7 January 2021

Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia

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Switch to unusual amino acids at codon 215 of the human immunodeficiency virus type 1 reverse transcriptase gene in seroconvertors infected with zidovudine-resistant variants

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7 January 2021

Loss of Viral Fitness Associated with Multiple Gag and Gag-Pol Processing Defects in Human Immunodeficiency Virus Type 1 Variants Selected for Resistance to Protease Inhibitors In Vivo

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7 January 2021

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11013760%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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