Resistance to human immunodeficiency virus type 1 protease inhibitors. (Q39559316)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

review article

1 reference

title

Resistance to human immunodeficiency virus type 1 protease inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

D Boden

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

M Markowitz

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

1 November 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

Antimicrobial Agents and Chemotherapy

6 December 2019

published in

1 reference

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6 December 2019

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

11

1 reference

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6 December 2019

page(s)

2775-2783

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.

6 December 2019

cites work

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Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease

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In vitro combination of PNU-140690, a human immunodeficiency virus type 1 protease inhibitor, with ritonavir against ritonavir-sensitive and -resistant clinical isolates

14 September 2017

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Activities of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor nelfinavir mesylate in combination with reverse transcriptase and protease inhibitors against acute HIV-1 infection in vitro

14 September 2017

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Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites

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14 September 2017

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Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease

14 September 2017

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Preclinical pharmacokinetics and distribution to tissue of AG1343, an inhibitor of human immunodeficiency virus type 1 protease

14 September 2017

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14 September 2017

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Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors

14 September 2017

1 reference

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Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.

14 September 2017

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L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor

14 September 2017

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Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor

14 September 2017

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Effect of point mutations on the kinetics and the inhibition of human immunodeficiency virus type 1 protease: relationship to drug resistance

14 September 2017

1 reference

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

14 September 2017

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

14 September 2017

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Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor

14 September 2017

1 reference

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Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group.

14 September 2017

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In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

14 September 2017

1 reference

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In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease

14 September 2017

1 reference

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Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

14 September 2017

1 reference

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Viral dynamics in human immunodeficiency virus type 1 infection

14 September 2017

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Rapid evolution of RNA genomes

14 September 2017

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On the size of the active site in proteases. I. Papain

14 September 2017

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A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins.

14 September 2017

1 reference

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Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor

14 September 2017

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14 September 2017

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Active human immunodeficiency virus protease is required for viral infectivity

14 September 2017

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14 September 2017

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14 September 2017

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Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution

14 September 2017

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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

14 September 2017

1 reference

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Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

14 September 2017

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14 September 2017

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14 September 2017

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HIV protease: a novel chemotherapeutic target for AIDS.

14 September 2017

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Properties of avian retrovirus particles defective in viral protease

14 September 2017

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Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays

14 September 2017

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Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells

14 September 2017

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14 September 2017

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Human immunodeficiency virus type 1 subtypes defined by env show high frequency of recombinant gag genes. The UNAIDS Network for HIV Isolation and Characterization

14 September 2017

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14 September 2017

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Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors

14 September 2017

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Expression of active human immunodeficiency virus type 1 protease by noninfectious chimeric virus particles.

14 September 2017

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In vivo selection of HIV-1 variants with reduced susceptibility to the protease inhibitor L-735,524 and related compounds.

25 September 2017

1 reference

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Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959.

25 September 2017

1 reference

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Impaired infectivity of HIV-1 after a single point mutation in the POL gene to escape the effect of a protease inhibitor in vitro

25 September 2017

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25 September 2017

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Human immunodeficiency virus. Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complex

15 June 2018

1 reference

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Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity

15 June 2018

1 reference

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15 June 2018

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Saquinavir/zidovudine combination in patients with advanced HIV infection and no prior antiretroviral therapy: CD4+ lymphocyte/plasma RNA changes, and emergence of HIV strains with reduced phenotypic sensitivity.

15 June 2018

1 reference

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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: mutations, kinetics, and frequencies

15 June 2018

1 reference

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Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. AIDS Clinical Trials Group

15 June 2018

1 reference

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Activated dynamics of flap opening in HIV-1 protease

15 June 2018

1 reference

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Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

Resistance of HIV Type 1 to Proteinase Inhibitor Ro 31-8959

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. European-Australian Collaborative Ritonavir Study Group

15 June 2018

1 reference

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Effective blocking of HIV-1 proteinase activity by characteristic inhibitors of aspartic proteinases

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

HTLV-III gag protein is processed in yeast cells by the virus pol-protease

15 June 2018

1 reference

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Murine leukemia virus maturation: protease region required for conversion from "immature" to "mature" core form and for virus infectivity

15 June 2018

1 reference

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Studies on the role of the S4 substrate binding site of HIV proteinases

15 June 2018

1 reference

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Ritonavir and saquinavir combination therapy for the treatment of HIV infection

15 June 2018

1 reference

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Kinetic characterization of human immunodeficiency virus type-1 protease-resistant variants

21 August 2018

1 reference

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A symmetric inhibitor binds HIV-1 protease asymmetrically

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

Flap opening in HIV-1 protease simulated by 'activated' molecular dynamics.

21 August 2018

1 reference

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Identification of an amino acid substitution involved in the reduction of sensitivity of HIV-1 to an inhibitor of viral proteinase.

21 August 2018

1 reference

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Three-dimensional Structure of a Mutant HIV-1 Protease Displaying Cross-resistance to All Protease Inhibitors in Clinical Trials

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

21 August 2018

Recombination in HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=105943

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9797203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9797203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.42.11.2775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9797203%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

PubMed publication ID

9797203

1 reference