Complexes between photoactivated rhodopsin and transducin: progress and questions (Q33873779)

29 July 2017

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title

Complexes between photoactivated rhodopsin and transducin: progress and questions (English)

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29 July 2017

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3

Krzysztof Palczewski

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29 July 2017

2

Yaroslav Tsybovsky

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29 July 2017

1

Beata Jastrzebska

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29 July 2017

language of work or name

English

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publication date

28 April 2010

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29 July 2017

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29 July 2017

volume

428

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29 July 2017

issue

1

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29 July 2017

page(s)

1-10

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Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation.

29 July 2017

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Direct observation of the pH-dependent equilibrium between metarhodopsins I and II and the pH-independent interaction of metarhodopsin II with transducin C-terminal peptide

5 July 2018

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The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways.

5 July 2018

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5 July 2018

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Structural waters define a functional channel mediating activation of the GPCR, rhodopsin.

5 July 2018

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Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors

5 July 2018

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Phospholipids are needed for the proper formation, stability, and function of the photoactivated rhodopsin-transducin complex

5 July 2018

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Comparative analysis of GPCR crystal structures

5 July 2018

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Different properties of the native and reconstituted heterotrimeric G protein transducin

5 July 2018

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Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin

5 July 2018

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

5 July 2018

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Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

5 July 2018

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Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer

5 July 2018

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Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain.

5 July 2018

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Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.

5 July 2018

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Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins

5 July 2018

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Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

5 July 2018

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Local peptide movement in the photoreaction intermediate of rhodopsin

5 July 2018

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G protein-coupled receptor rhodopsin

5 July 2018

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Crystallographic analysis of primary visual photochemistry

5 July 2018

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Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors

5 July 2018

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Functional and structural characterization of rhodopsin oligomers

5 July 2018

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Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface

5 July 2018

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Rhodopsin self-associates in asolectin liposomes

5 July 2018

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Imaging nanometer domains of beta-adrenergic receptor complexes on the surface of cardiac myocytes

5 July 2018

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Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells

5 July 2018

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Computational modeling approaches to structure-function analysis of G protein-coupled receptors

5 July 2018

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5 July 2018

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The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes

5 July 2018

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Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy

5 July 2018

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Functional characterization of rhodopsin monomers and dimers in detergents

5 July 2018

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Probing rhodopsin-transducin interactions by surface modification and mass spectrometry

5 July 2018

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Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

5 July 2018

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Electron crystallography reveals the structure of metarhodopsin I.

5 July 2018

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The G protein-coupled receptor rhodopsin in the native membrane

5 July 2018

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Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

5 July 2018

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Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking

5 July 2018

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G protein-coupled receptor rhodopsin: a prospectus

5 July 2018

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G proteins and phototransduction.

5 July 2018

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Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance

5 July 2018

1 reference

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Activation of rhodopsin: new insights from structural and biochemical studies

5 July 2018

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Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin

5 July 2018

1 reference

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Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent

5 July 2018

1 reference

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Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent

5 July 2018

1 reference

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Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.

5 July 2018

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

5 July 2018

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Light transduction in invertebrate hyperpolarizing photoreceptors: possible involvement of a Go-regulated guanylate cyclase

5 July 2018

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X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles.

5 July 2018

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Presence of Two Rhodopsin Intermediates Responsible for Transducin Activation

5 July 2018

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Surface plasmon resonance spectroscopy studies of membrane proteins: transducin binding and activation by rhodopsin monitored in thin membrane films

5 July 2018

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Role of the prenyl group on the G protein gamma subunit in coupling trimeric G proteins to A1 adenosine receptors

5 July 2018

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Receptor and membrane interaction sites on Gbeta. A receptor-derived peptide binds to the carboxyl terminus

5 July 2018

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5 July 2018

How photons start vision

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Interaction of rhodopsin with the G-protein, transducin

5 July 2018

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Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state

5 July 2018

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Modulation of rhodopsin function by properties of the membrane bilayer

5 July 2018

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Force-induced conformational change of bacteriorhodopsin

5 July 2018

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Nobel Lecture. Signal transduction: evolution of an idea

5 July 2018

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Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes

5 July 2018

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Flow of information in the light-triggered cyclic nucleotide cascade of vision

5 July 2018

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Effect of GTP on the rhodopsin-G-protein complex by transient formation of extra metarhodopsin II

5 July 2018

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The G-protein of retinal rod outer segments (transducin). Mechanism of interaction with rhodopsin and nucleotides.

5 July 2018

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Kinetic study on the equilibrium between membrane-bound and free photoreceptor G-protein

5 July 2018

1 reference

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Lipid-protein interactions mediate the photochemical function of rhodopsin

5 July 2018

1 reference

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G proteins: transducers of receptor-generated signals

5 July 2018

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The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin.

5 July 2018

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Molecular dynamics simulations in biology

5 July 2018

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G protein-coupled mechanisms and nervous signaling

5 July 2018

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Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins

5 July 2018

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Proton transfer reactions linked to rhodopsin activation.

5 July 2018

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Direct observation of the complex formation of GDP-bound transducin with the rhodopsin intermediate having a visible absorption maximum in rod outer segment membranes.

21 January 2018

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Two-step mechanism of interaction of rhodopsin intermediates with the C-terminal region of the transducin alpha-subunit.

21 January 2018

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Conformational dynamics of the nicotinic acetylcholine receptor channel: a 35-ns molecular dynamics simulation study

21 January 2018

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Interaction of a G protein-coupled receptor with a G protein-derived peptide induces structural changes in both peptide and receptor: a Fourier-transform infrared study using isotopically labeled peptides.

21 January 2018

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Light-induced, reversible binding of proteins to bovine photoreceptor membranes. Influence of nucleotides

21 January 2018

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Dark and photoactivated rhodopsin share common binding modes to transducin

21 January 2018

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A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

21 January 2018

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Mesoscopic Monte Carlo simulations of stochastic encounters between photoactivated rhodopsin and transducin in disc membranes.

21 January 2018

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The Gbetagamma dimer drives the interaction of heterotrimeric Gi proteins with nonlamellar membrane structures

21 January 2018

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Electrostatic and lipid anchor contributions to the interaction of transducin with membranes: mechanistic implications for activation and translocation.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20100270

Electrostatic properties of membrane lipids coupled to metarhodopsin II formation in visual transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100270

Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20100270

Optimization of receptor-G protein coupling by bilayer lipid composition I: kinetics of rhodopsin-transducin binding

21 January 2018

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Visual pigment: G-protein-coupled receptor for light signals

29 October 2018

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Cooperative binding of the retinal rod G-protein, transducin, to light-activated rhodopsin

29 October 2018

1 reference

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Introduction of King-Wai Yau 1993 Friedenwald Award winner.

29 October 2018

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Opsin Stability and Folding: Modulation by Phospholipid Bicelles

29 October 2018

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https://api.crossref.org/works/10.1042%2FBJ20100270

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20100270

Rhodopsin dimers in native disc membranes

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20100270

Voltage and pH-induced channel closure of porin OmpF visualized by atomic force microscopy

21 January 2018

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12 December 2020

Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit

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12 December 2020

Transducin interactions with rhodopsin. Evidence for positive cooperative behavior

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12 December 2020

Metarhodopsin-II stabilization by crosslinked Gtalpha C-terminal peptides and implications for the mechanism of GPCR-G protein coupling

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12 December 2020

The receptor-bound "empty pocket" state of the heterotrimeric G-protein alpha-subunit is conformationally dynamic

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12 December 2020

Identification of a new intermediate state that binds but not activates transducin in the bleaching process of bovine rhodopsin

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12 December 2020

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12 December 2020

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12 December 2020

Role of G-protein-receptor interaction in amplified phosphodiesterase activation of retinal rods

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12 December 2020

Rhodopsin activation follows precoupling with transducin: inferences from computational analysis

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12 December 2020

Lipid headgroup and acyl chain composition modulate the MI-MII equilibrium of rhodopsin in recombinant membranes

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12 December 2020

Activation of G-protein Galpha subunits by receptors through Galpha-Gbeta and Galpha-Ggamma interactions

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12 December 2020

Light-dependent interactions between rhodopsin and photoreceptor enzymes

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12 December 2020

Identifiers

DOI

10.1042/BJ20100270

1 reference

29 July 2017

1 reference

29 July 2017

1 reference