A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity (Q33861971)

29 July 2017

title

A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity (English)

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29 July 2017

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Lotem J

1

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29 July 2017

Sachs L

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 October 1995

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

92

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29 July 2017

issue

21

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29 July 2017

page(s)

9672-9676

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p53 is required for radiation-induced apoptosis in mouse thymocytes

29 July 2017

cites work

1 reference

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Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin

5 July 2018

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Control of programmed cell death in normal and leukemic cells: new implications for therapy.

5 July 2018

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Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression

5 July 2018

1 reference

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Gain of function mutations in p53.

5 July 2018

1 reference

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Mediation of c-Myc-induced apoptosis by p53.

5 July 2018

1 reference

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The adventures of a biologist: prenatal diagnosis, hematopoiesis, leukemia, carcinogenesis, and tumor suppression.

5 July 2018

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Apoptosis and macrophage-mediated deletion of precursor B cells in the bone marrow of E mu-myc transgenic mice

5 July 2018

1 reference

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The nucleotide sequence of the rat cytoplasmic β–actin gene

5 July 2018

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Evolution of tumours and the impact of molecular oncology

5 July 2018

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High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

5 July 2018

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

5 July 2018

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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

5 July 2018

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The p53 tumour suppressor gene

5 July 2018

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Transgenic models of tumor development.

5 July 2018

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Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis

5 July 2018

1 reference

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

5 July 2018

1 reference

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BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense

5 July 2018

1 reference

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Induction of apoptosis in fibroblasts by c-myc protein

5 July 2018

1 reference

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

5 July 2018

1 reference

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Apoptotic cell death induced by c-myc is inhibited by bcl-2.

5 July 2018

1 reference

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p53: the ultimate tumor suppressor gene?

5 July 2018

1 reference

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

5 July 2018

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Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells.

29 October 2018

1 reference

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Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents

29 October 2018

1 reference

12 December 2020

Coming to terms with death: apoptosis in cancer and immune development

1 reference

12 December 2020

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

1 reference

12 December 2020

Deregulated c-myc expression abrogates the interferon- and interleukin 6-mediated G0/G1 cell cycle arrest but not other inhibitory responses in M1 myeloblastic cells

1 reference

12 December 2020

Checkpoints of dueling dimers foil death wishes

1 reference

12 December 2020

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1 reference

12 December 2020

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.21.9672

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29 July 2017

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29 July 2017

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