Evolution of tumours and the impact of molecular oncology (Q39494403)

12 September 2017

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title

Evolution of tumours and the impact of molecular oncology (English)

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12 September 2017

Klein G

1

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12 September 2017

Klein E

series ordinal

2

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12 September 2017

language of work or name

English

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publication date

1 May 1985

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12 September 2017

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12 September 2017

volume

315

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12 September 2017

issue

6016

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12 September 2017

page(s)

190-195

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The natural history of cancer

12 September 2017

cites work

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7 January 2021

The clonal evolution of tumor cell populations

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7 January 2021

A COMPARISON OF VIRUS-INDUCED RABBIT TUMORS WITH THE TUMORS OF UNKNOWN CAUSE ELICITED BY TARRING

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7 January 2021

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

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7 January 2021

Retinoblastoma: Clues to Human Oncogenesis

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7 January 2021

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

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Mutation and cancer: statistical study of retinoblastoma

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A general theory of carcinogenesis

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7 January 2021

Oncogenetics: progress in malignancy

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7 January 2021

Suppression of Malignancy by Cell Fusion

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7 January 2021

Suppression of malignancy in human cells

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7 January 2021

The role of chromosome 15 in murine leukemogenesis. I. Contrasting behavior of the tumor vs. normal parent‐derived chromosomes no. 15 in somatic hybrids of varying tumorigenicity

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7 January 2021

Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes

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7 January 2021

Final case reporting from the ugandan prospective study of the relationship between ebv and burktit's lymphoma

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7 January 2021

Oncogene activation and tumor progression

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7 January 2021

Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men.

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7 January 2021

The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors

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7 January 2021

Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas.

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7 January 2021

Biological differences between epstein-barr virus (EBV) strains with regard to lymphocyte transforming ability, superinfection and antigen induction

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7 January 2021

Characterization of a second Epstein-Barr virus-determined nuclear antigen associated with the BamHI WYH region of EBV DNA.

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7 January 2021

One of two Epstein-Barr virus nuclear antigens contains a glycine-alanine copolymer domain

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7 January 2021

Stable expression in mouse cells of nuclear neoantigen after transfer of a 3.4-megadalton cloned fragment of Epstein-Barr virus DNA

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7 January 2021

Immortalized B lymphocytes produce B-cell growth factor.

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7 January 2021

Autocrine growth factors and cancer

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7 January 2021

Capacity of B-lymphocytic lines of diverse tumor origin to produce and respond to B-cell growth factors: a progression model for B-cell lymphomagenesis

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7 January 2021

Translocations among antibody genes in human cancer

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7 January 2021

Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas

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7 January 2021

Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors.

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7 January 2021

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

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7 January 2021

Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas

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7 January 2021

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma

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7 January 2021

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

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7 January 2021

Molecular cloning of translocations involving chromosome 15 and the immunoglobulin C alpha gene from chromosome 12 in two murine plasmacytomas

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7 January 2021

Non-immunoglobulin-associated DNA rearrangements in mouse plasmacytomas

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7 January 2021

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

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7 January 2021

Consequences of myc invasion of immunoglobulin loci: facts and speculation

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7 January 2021

Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt

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7 January 2021

Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription

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7 January 2021

The 2p breakpoint of a 2;8 translocation in Burkitt lymphoma interrupts the V kappa locus

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7 January 2021

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7 January 2021

Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.

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7 January 2021

Message of myc in context

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7 January 2021

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

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7 January 2021

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

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7 January 2021

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

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7 January 2021

Chromosome translocations and human cancer

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7 January 2021

Lymphoma development in mice and humans: diversity of initiation is followed by convergent cytogenetic evolution

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7 January 2021

The role of gene dosage and genetic transpositions in carcinogenesis

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7 January 2021

Phenotypic and Cytogenetic Characteristics of Human B-Lymphoid Cell Lines and Their Relevance for the Etiology of Burkitt'S Lymphoma

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7 January 2021

A novel 6:10 chromosomal translocation in the murine plasmacytoma NS-1.

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7 January 2021

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element

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7 January 2021

Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome

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7 January 2021

Chromosomal translocations activating myc sequences and transduction of v-abl are critical events in the rapid induction of plasmacytomas by pristane and abelson virus

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7 January 2021

DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas

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7 January 2021

Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation

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7 January 2021

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

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7 January 2021

Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23)

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7 January 2021

Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

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7 January 2021

Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells

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7 January 2021

The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4

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7 January 2021

Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient

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7 January 2021

Isolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes.

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7 January 2021

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

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7 January 2021

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

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7 January 2021

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma

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7 January 2021

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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7 January 2021

Experimental elimination and recovery of double minute chromosomes in malignant cell populations

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7 January 2021

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

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7 January 2021

Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals

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7 January 2021

Further evidence favoring the concept of the stem cell in ascites tumors of rats

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7 January 2021

Nonrandom chromosomal abnormalities in hematologic disorders of man

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7 January 2021

G-banding in Rous rat sarcomas during serial transfer: Significant chromosome aberrations and incidence of stromal mitoses

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7 January 2021

A clonal complete remission in a patient with acute nonlymphocytic leukemia originating in a multipotent stem cell

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7 January 2021

Chromosomal localization of human cellular homologues of two viral oncogenes.

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7 January 2021

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

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7 January 2021

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

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7 January 2021

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

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7 January 2021

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

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7 January 2021

Altered transcription of an oncogene in chronic myeloid leukaemia

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7 January 2021

Clustering of aberrations to specific chromosomes in human neoplasms

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7 January 2021

Chromosome Changes (Trisomies #15 and 17) Associated With Tumor Progression in Leukemias Induced by Radiation Leukemia Virus2

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7 January 2021

Chromosome changes (trisomy 15) in murine T-cell leukemia induced by 7,12-dimethylbenz(a)anthracene (DMBA)

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7 January 2021

Rat c-myc oncogene is located on chromosome 7 and rearranges in immunocytomas with t(6:7) chromosomal translocation

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7 January 2021

Interchromosomal recombination of the cellular oncogene c-myc with the immunoglobulin heavy chain locus in murine plasmacytomas is a reciprocal exchange

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7 January 2021

Immune surveillance against virus-induced tumors and nonrejectability of spontaneous tumors: contrasting consequences of host versus tumor evolution

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7 January 2021

Epstein-Barr-virus-carrying lymphoma in cardiac transplant recipient

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7 January 2021

Detection of an Epstein-Barr virus-associated membrane antigen in Epstein-Barr virus-transformed nonproducer cells by leukocyte migration inhibition and blocking antibody

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7 January 2021

Kaposi's sarcoma and its relationship to cytomegalovirus (CMNV). III. CMV DNA and CMV early antigens in Kaposi's sarcoma.

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7 January 2021

Role of nk cells in the antimetastatic effect of anticoagulant drugs

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7 January 2021

Reduced humoral and cellular cytotoxic sensitivity in histocompatibility variants of the YAC (Moloney) lymphoma.

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7 January 2021

Identifiers

DOI

10.1038/315190A0

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12 September 2017

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