Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development (Q33850170)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development (English)

1 reference

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8 January 2020

3

1 reference

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8 January 2020

author name string

Sean Rooney

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Frederick W Alt

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

John P Manis

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

7 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

102

1 reference

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8 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

2471-2475

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

ATM is required for efficient recombination between immunoglobulin switch regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Phosphorylation of Artemis following irradiation-induced DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

The role of the non-homologous end-joining pathway in lymphocyte development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

53BP1 is required for class switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

A means to a DNA end: the many roles of Ku.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Unraveling V(D)J recombination; insights into gene regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

The role of DNA dependent protein kinase in synapsis of DNA ends.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Impact of DNA ligase IV on the fidelity of end joining in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

The Greek Goddess, Artemis, reveals the secrets of her cleavage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Defining interactions between DNA-PK and ligase IV/XRCC4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Synapsis of DNA ends by DNA-dependent protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Genomic instability in mice lacking histone H2AX

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Mechanism and control of class-switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Signal joint formation is also impaired in DNA-dependent protein kinase catalytic subunit knockout cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Ku80 is required for immunoglobulin isotype switching

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

High expression of a 3'----5' exonuclease activity is specific to B lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548986

Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

B cell development under the condition of allelic inclusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

Ig heavy chain class switching in Rag-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409857102

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15699324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15699324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15699324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0409857102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15699324%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

15699324

1 reference