A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor. (Q33822395)

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English	A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor.	scientific article

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1 November 2019

A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor (English)

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1 November 2019

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Alexandra Trkola

1

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1 November 2019

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J Matthews

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1 November 2019

C Gordon

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1 November 2019

T Ketas

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1 November 2019

J P Moore

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1 November 1999

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1 November 2019

Journal of Virology

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1 November 2019

73

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1 November 2019

11

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1 November 2019

8966-8974

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1 November 2019

describes a project that uses

0 references

The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity

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HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy

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Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.

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Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages

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Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling

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Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies.

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Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?

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Study of the V3 loop as a target epitope for antibodies involved in the neutralization of primary isolates versus T-cell-line-adapted strains of human immunodeficiency virus type 1

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What immunity can protect against HIV infection

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Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

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HIV vaccines--where are we going?

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Cationic liposomes enhance the rate of transduction by a recombinant retroviral vector in vitro and in vivo

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4 July 2018

Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans

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4 July 2018

Coreceptor utilization by human immunodeficiency virus type 1 is not a primary determinant of neutralization sensitivity

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4 July 2018

Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage

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4 July 2018

Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage.

1 reference

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4 July 2018

The antibody response in HIV-1 infection.

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4 July 2018

A new classification for HIV-1

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4 July 2018

AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.

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Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines.

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4 July 2018

Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.

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4 July 2018

A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor

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4 July 2018

A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection

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Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

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4 July 2018

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

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A vaccine for HIV type 1: The antibody perspective

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4 July 2018

Expression cloning of new receptors used by simian and human immunodeficiency viruses

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4 July 2018

Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses

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4 July 2018

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

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A new reporter cell line to monitor HIV infection and drug susceptibility in vitro

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Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals.

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The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

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Antibody-mediated neutralization of primary isolates of human immunodeficiency virus type 1 in peripheral blood mononuclear cells is not affected by the initial activation state of the cells

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4 July 2018

Infectious properties of human immunodeficiency virus type 1 mutants with distinct affinities for the CD4 receptor

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CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1.

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Consistent and high rates of gene transfer can be obtained using flow-through transduction over a wide range of retroviral titers

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HIV-1 neutralization: the consequences of viral adaptation to growth on transformed T cells.

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4 July 2018

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

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4 July 2018

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

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4 July 2018

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

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4 July 2018

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

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4 July 2018

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

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Differential role of V3-specific antibodies in neutralization assays involving primary and laboratory-adapted isolates of HIV type 1.

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Toward an understanding of the correlates of protective immunity to HIV infection

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Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera

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Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.

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4 July 2018

Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.

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4 July 2018

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.

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4 July 2018

Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

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4 July 2018

Retrovirus infection: effect of time and target cell number

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Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

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Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

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Optimal conditions for recovery of the human immunodeficiency virus from peripheral blood mononuclear cells

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4 July 2018

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates

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4 July 2018

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Adhesion receptors of the immune system

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Penetration of CD4 T cells by HIV-1. The CD4 receptor does not internalize with HIV, and CD4-related signal transduction events are not required for entry

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29 October 2018

HIV-1 neutralizing antibodies: how full is the bottle?

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29 October 2018

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Progress in the development of an HIV-1 vaccine

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29 October 2018

Toward an HIV type 1 vaccine that generates potent, broadly cross-reactive neutralizing antibodies

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and Characterization of CD4-IgG2, a Novel Heterotetramer That Neutralizes Primary HIV Type 1 Isolates

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https://pubmed.ncbi.nlm.nih.gov/10516002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A resting cell assay for improved detection of antibody-mediated neutralization of HIV type 1 primary isolates

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https://pubmed.ncbi.nlm.nih.gov/10516002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of HIV-1 infection with a green fluorescent protein reporter system

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https://pubmed.ncbi.nlm.nih.gov/10516002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression patterns of the HIV type 1 coreceptors CCR5 and CXCR4 on CD4+ T cells and monocytes from cord and adult blood

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 November 2019

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1 November 2019

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