Base excision repair of tandem modifications in a methylated CpG dinucleotide. (Q33619413)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24695738%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Base excision repair of tandem modifications in a methylated CpG dinucleotide (English)

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12 March 2020

5

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12 March 2020

author name string

Akira Sassa

1

1 reference

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12 March 2020

Melike Çağlayan

2

1 reference

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12 March 2020

Nadezhda S Dyrkheeva

3

1 reference

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12 March 2020

William A Beard

4

1 reference

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12 March 2020

language of work or name

English

0 references

publication date

2 April 2014

1 reference

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Journal of Biological Chemistry

12 March 2020

published in

1 reference

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12 March 2020

volume

289

1 reference

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12 March 2020

issue

20

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12 March 2020

page(s)

13996-14008

1 reference

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describes a project that uses

12 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4022870/fullTextXML

inferred from PubMed Central ID database lookup

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Steady-state, pre-steady-state, and single-turnover kinetic measurement for DNA glycosylase activity

21 June 2018

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Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming

21 June 2018

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DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase

21 June 2018

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Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency

21 June 2018

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Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA

21 June 2018

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Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

21 June 2018

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Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion

21 June 2018

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Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

21 June 2018

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Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

21 June 2018

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Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.

21 June 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 June 2018

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Epigenetics, oxidative stress, and Alzheimer disease

21 June 2018

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Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex

21 June 2018

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Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition

21 June 2018

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Defective responses to DNA single- and double-strand breaks in spinocerebellar ataxia

21 June 2018

1 reference

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Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA.

21 June 2018

1 reference

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Cyclical DNA methylation of a transcriptionally active promoter

21 June 2018

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Defective DNA repair and neurodegenerative disease

21 June 2018

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Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Actions of aprataxin in multiple DNA repair pathways

21 June 2018

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Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes

21 June 2018

1 reference

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Futile short-patch DNA base excision repair of adenine:8-oxoguanine mispair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

21 June 2018

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Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

21 June 2018

1 reference

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The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: a role for UVA in human skin carcinogenesis

21 June 2018

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

21 June 2018

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The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Truncation of amino-terminal tail stimulates activity of human endonuclease III (hNTH1)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Worms gang up on bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Base excision repair in a network of defence and tolerance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Substrate specificity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Mutation hotspots and DNA methylation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Effect of oxidative DNA damage in promoter elements on transcription factor binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

DNA methylation directs a time-dependent repression of transcription initiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Sp1 binding is inhibited by (m)Cp(m)CpG methylation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

DNA methylation: a molecular lock

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Mutagenic and epigenetic effects of DNA methylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Purification and domain-mapping of mammalian DNA polymerase beta.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Free radical adducts induce alterations in DNA cytosine methylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Gene number, noise reduction and biological complexity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Number of CpG islands and genes in human and mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

The CpG dinucleotide and human genetic disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

The essentials of DNA methylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022870

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Kinetics of the action of thymine DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Excision of 8-oxoguanine from methylated CpG dinucleotides by human 8-oxoguanine DNA glycosylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Mismatch uracil glycosylase from Escherichia coli: a general mismatch or a specific DNA glycosylase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

Involvement of flap endonuclease 1 in base excision DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

21 January 2018

Rare Bases in Animal DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.557769

DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.

21 January 2018

1 reference

12 December 2020

Carbon-13 magnetic resonance spectra of 8-substituted purine nucleosides. Characteristic shifts for the syn conformation

1 reference

12 December 2020

A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine

1 reference

12 December 2020

Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism

1 reference

12 December 2020

Pre-steady-state kinetic characterization of the AP endonuclease activity of human AP endonuclease 1

1 reference

12 December 2020

The fundamental role of epigenetic events in cancer

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.557769

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24695738%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24695738%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24695738

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24695738%20AND%20SRC:MED&resulttype=core&format=json