WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1. (Q33580323)

28 July 2017

title

WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1. (English)

1 reference

28 July 2017

Luxi Sun

1

1 reference

28 July 2017

Satoshi Nakajima

2

1 reference

28 July 2017

Yaqun Teng

3

1 reference

28 July 2017

Hao Chen

4

1 reference

28 July 2017

Lu Yang

5

1 reference

28 July 2017

Xiukai Chen

6

1 reference

28 July 2017

Boya Gao

7

1 reference

28 July 2017

Arthur S Levine

8

1 reference

28 July 2017

Li Lan

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 February 2017

1 reference

28 July 2017

published in

Nucleic Acids Research

1 reference

28 July 2017

volume

45

1 reference

28 July 2017

issue

7

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28 July 2017

page(s)

3844-3859

1 reference

Creative Commons Attribution-NonCommercial 4.0 International

28 July 2017

copyright license

start time

1 February 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A continuous correlation between oxidative stress and telomere shortening in fibroblasts

21 June 2018

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Telomere dysfunction as a cause of genomic instability in Werner syndrome

21 June 2018

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Quadruplex DNA: sequence, topology and structure

21 June 2018

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Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain

21 June 2018

1 reference

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Accumulation of Werner protein at DNA double-strand breaks in human cells

21 June 2018

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21 June 2018

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21 June 2018

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The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.

21 June 2018

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Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

21 June 2018

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21 June 2018

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Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein

21 June 2018

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Essential role of limiting telomeres in the pathogenesis of Werner syndrome

21 June 2018

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The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Resolution of sister telomere association is required for progression through mitosis

21 June 2018

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Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Physical and functional interaction of the Werner syndrome protein with poly‐ADP ribosyl transferase

21 June 2018

1 reference

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21 June 2018

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21 June 2018

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Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

21 June 2018

1 reference

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The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity

21 June 2018

1 reference

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Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Solution structure of a telomeric DNA complex of human TRF1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2

21 June 2018

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The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 June 2018

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Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene

21 June 2018

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WRN mutations in Werner syndrome

21 June 2018

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Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein – Barr virus

21 June 2018

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Control of telomere length by the human telomeric protein TRF1

21 June 2018

1 reference

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 June 2018

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Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

21 June 2018

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Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed.

21 June 2018

1 reference

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The ACF1 Complex Is Required for DNA Double-Strand Break Repair in Human Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX065

WRN mutations in Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX065

A conserved G4 DNA binding domain in RecQ family helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKX065

Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5397154

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28158503

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKX065

1 reference

28 July 2017

1 reference

28 July 2017

1 reference