Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility (Q28584900)

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English	Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility	scientific journal article

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scholarly article

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PubMed publication ID

31 January 2017

Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility (English)

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PubMed publication ID

31 January 2017

Adenomatous polyposis coli protein

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GOA release 2020-03-11

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GOA release 2020-03-11

Catenin (cadherin associated protein), beta 1

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GOA release 2020-03-11

Monica Bertagnolli

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object named as

Monica M. Bertagnolli

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PubMed publication ID

31 January 2017

author name string

Adelaide M. Carothers

1

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PubMed publication ID

31 January 2017

Sara H. Javid

2

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PubMed publication ID

31 January 2017

Amy E. Moran

3

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PubMed publication ID

31 January 2017

Daniel H. Hunt

4

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PubMed publication ID

31 January 2017

Mark Redston

5

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PubMed publication ID

31 January 2017

language of work or name

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publication date

15 February 2006

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PubMed publication ID

31 January 2017

Experimental Cell Research

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PubMed publication ID

31 January 2017

312

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PubMed publication ID

31 January 2017

4

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PubMed publication ID

31 January 2017

387–400

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PubMed publication ID

31 January 2017

Live and let die in the intestinal epithelium

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The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium.

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Adenomatous polyposis coli proteins and cell adhesion

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Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion.

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Regulation of cadherin adhesive activity

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7 January 2021

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

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The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

1 reference

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Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system

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E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice

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Oncogenic growth factor receptors: implications for signal transduction therapy

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Prostanoid receptor signaling relevant to tumor growth and angiogenesis

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Density-dependent inhibition of growth involves prevention of EGF receptor activation by E-cadherin-mediated cell-cell adhesion

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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

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The Epidermal Growth Factor Receptor Modulates the Interaction of E-cadherin with the Actin Cytoskeleton

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Regulation of epithelial cell migration and tumor formation by beta-catenin signaling

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

1 reference

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Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors

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Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice

1 reference

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Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

1 reference

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Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

1 reference

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Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

1 reference

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1 reference

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Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.

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Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade

1 reference

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Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics

1 reference

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Cadherin engagement regulates Rho family GTPases

1 reference

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Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family

1 reference

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Membrane targeting of p21-activated kinase 1(PAK1) induces neurite outgrowth from PC12 cells

1 reference

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Rho and Rac take center stage

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Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

1 reference

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The G-protein G13 but Not G12 Mediates Signaling from Lysophosphatidic Acid Receptor via Epidermal Growth Factor Receptor to Rho

1 reference

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

1 reference

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1 reference

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: role of Ca2+, PKC, and Rho kinase

1 reference

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Myosin-dependent contractile activity of the actin cytoskeleton modulates the spatial organization of cell-cell contacts in cultured epitheliocytes

1 reference

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

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Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

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Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells

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Mutated APC and Asef are involved in the migration of colorectal tumour cells

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Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

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Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

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Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

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Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

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Intestinal adenomas can develop with a stable karyotype and stable microsatellites

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Identifiers

10.1016/J.YEXCR.2005.11.019

1 reference

PubMed publication ID

31 January 2017

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

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