Cell signaling by receptor tyrosine kinases (Q24598357)

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

Europe PubMed Central

title

Cell signaling by receptor tyrosine kinases (English)

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author

Joseph Schlessinger

series ordinal

2

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Mark A. Lemmon

object named as

Mark A Lemmon

series ordinal

1

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language of work or name

English

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publication date

25 June 2010

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published in

Cell

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volume

141

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issue

7

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page(s)

1117-34

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cites work

1 reference

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The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site

24 March 2017

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Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment

24 March 2017

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Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases

24 March 2017

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Mechanism of activation and inhibition of the HER4/ErbB4 kinase

24 March 2017

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A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation

24 March 2017

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Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

24 March 2017

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Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors

24 March 2017

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An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

24 March 2017

1 reference

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A comprehensive pathway map of epidermal growth factor receptor signaling

24 March 2017

1 reference

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Structural basis for Gas6-Axl signalling.

24 March 2017

1 reference

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A quantitative protein interaction network for the ErbB receptors using protein microarrays

24 March 2017

1 reference

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The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand

24 March 2017

1 reference

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Cellular signaling by fibroblast growth factor receptors

24 March 2017

1 reference

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Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization

24 March 2017

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

24 March 2017

1 reference

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

24 March 2017

1 reference

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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

24 March 2017

1 reference

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Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

24 March 2017

1 reference

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Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structural interactions of fibroblast growth factor receptor with its ligands

24 March 2017

1 reference

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Structural basis for FGF receptor dimerization and activation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The discoidin domain receptor tyrosine kinases are activated by collagen

24 March 2017

1 reference

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Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

24 March 2017

1 reference

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Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structural determinants of growth factor binding and specificity by VEGF receptor 2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinases

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The structural basis for autoinhibition of FLT3 by the juxtamembrane domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure of the extracellular region of HER3 reveals an interdomain tether

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure and autoregulation of the insulin-like growth factor 1 receptor kinase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The conformational plasticity of protein kinases

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Cell signaling by receptor tyrosine kinases

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Protein modules and signalling networks

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Signal transduction by receptors with tyrosine kinase activity

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Lrp4 is a receptor for Agrin and forms a complex with MuSK

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure and chemical inhibition of the RET tyrosine kinase domain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

EGF-dependent association of phospholipase C-gamma1 with c-Cbl

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Oncogenic kinase signalling

24 March 2017

1 reference

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Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling

24 March 2017

1 reference

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An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

24 March 2017

1 reference

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Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

24 March 2017

1 reference

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Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Eph signaling: a structural view

24 March 2017

1 reference

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The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

24 March 2017

1 reference

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Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

24 March 2017

1 reference

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

7 April 2017

1 reference

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Epidermal growth factor receptor mutations in lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Protein tyrosine phosphatases: from genes, to function, to disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Ubiquitin-binding domains

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

EGF-ERBB signalling: towards the systems level

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

7 April 2017

Biological robustness

1 reference

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Regulation of protein kinases; controlling activity through activation segment conformation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Reading protein modifications with interaction domains

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction

7 April 2017

1 reference

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Systems biology of growth factor-induced receptor endocytosis

10 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Quantitative modeling perspectives on the ErbB system of cell regulatory processes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma

27 September 2017

1 reference

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Signaling from endosomes: location makes a difference.

27 September 2017

1 reference

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Phosphoproteomics: unraveling the signaling web.

27 September 2017

1 reference

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Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation.

27 September 2017

1 reference

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Alternative wnt signaling is initiated by distinct receptors.

27 September 2017

1 reference

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ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling

27 September 2017

1 reference

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Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Acquired resistance to tyrosine kinase inhibitors during cancer therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The age of crosstalk: phosphorylation, ubiquitination, and beyond

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Molecular pathobiology of gastrointestinal stromal sarcomas.

27 September 2017

1 reference

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The HER family and cancer: emerging molecular mechanisms and therapeutic targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

EGF receptor ubiquitination is not necessary for its internalization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases

27 September 2017

1 reference

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Development trends for monoclonal antibody cancer therapeutics.

27 September 2017

1 reference

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Sunitinib: from rational design to clinical efficacy

27 September 2017

1 reference

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Dynamic control of signaling by modular adaptor proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Role of ubiquitin- and Ubl-binding proteins in cell signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The insulin and EGF receptor structures: new insights into ligand-induced receptor activation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Targeting ADAMS and ERBBs in lung cancer

27 September 2017

1 reference

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MAPK signal specificity: the right place at the right time

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Mutations in different components of FGF signaling in LADD syndrome

27 September 2017

1 reference

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Cell-signalling dynamics in time and space

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors

27 September 2017

1 reference

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Regulating the dynamics of EGF receptor signaling in space and time

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

27 September 2017

1 reference

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Robustness of cellular functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Not just a sink: endosomes in control of signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Juxtamembrane autoinhibition in receptor tyrosine kinases.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Platelet-derived growth factor receptor-mediated signal transduction from endosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

SH2 and PTB domains in tyrosine kinase signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The "Gab" in signal transduction.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Smart drugs: tyrosine kinase inhibitors in cancer therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Searching for specificity in SH domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Signaling on the endocytic pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

A module of negative feedback regulators defines growth factor signaling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Switching on kinases: oncogenic activation of BRAF and the PDGFR family

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Structure and specificity of the SH2 domain

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

ZIP codes for delivering SH2 domains

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

28 November 2018

All signaling is local?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Signal transduction. Are there close encounters between signaling pathways?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Autophosphorylation activates the soluble cytoplasmic domain of the insulin receptor in an intermolecular reaction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914105

Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20602996

12 December 2020

inferred from PubMed ID database lookup

Studies on carcinogenesis by avian sarcoma viruses. 3. The differential effect of serum and polyanions on multiplication of uninfected and converted cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20602996

12 December 2020

inferred from PubMed ID database lookup

Endocytosis and intracellular trafficking of ErbBs

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.06.011

7 January 2021

inferred from DOI database lookup

Folding and stability of the Z and S(iiyama) genetic variants of human alpha1-antitrypsin

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.06.011

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.CELL.2010.06.011

1 reference

1 reference

1 reference

PubMed publication ID

20602996

1 reference