Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling (Q28213808)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313945%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling (English)

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6 November 2019

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1

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6 November 2019

Silvia Giordano

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Peter Joseph Jacques Parker

6 November 2019

4

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6 November 2019

Paolo M. Comoglio

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6 November 2019

author name string

Anguissola S

3

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6 November 2019

language of work or name

English

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publication date

1 January 2001

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6 November 2019

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6 November 2019

volume

20

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6 November 2019

issue

2

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6 November 2019

page(s)

156-166

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Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

6 November 2019

cites work

1 reference

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Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

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Diversity in function and regulation of MAP kinase pathways

21 January 2018

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Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

21 January 2018

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p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

21 January 2018

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Protein Kinase C Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation Requires Serine 612

21 January 2018

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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PI3K: downstream AKTion blocks apoptosis

21 January 2018

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Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

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Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene

21 January 2018

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Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

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Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

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Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling

21 January 2018

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A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

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Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

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Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

21 January 2018

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The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

21 January 2018

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Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

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The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

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The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro

21 January 2018

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Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

21 January 2018

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Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

21 January 2018

1 reference

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Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356

21 January 2018

1 reference

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

21 January 2018

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14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain

21 January 2018

1 reference

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Multiple pathways control protein kinase C phosphorylation

21 January 2018

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

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Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

21 January 2018

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DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

21 January 2018

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Regulation of recombinant PKC alpha activity by protein phosphatase 1 and protein phosphatase 2A.

21 January 2018

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Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

21 January 2018

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Mitogen-activated protein kinase pathways

21 January 2018

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Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation

21 January 2018

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Activated ERK2 interacts with and phosphorylates the docking protein GAB1.

21 January 2018

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Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

21 January 2018

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Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

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Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

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Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

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HGF: a multifunctional growth factor controlling cell scattering.

21 January 2018

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Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

21 January 2018

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Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells

21 January 2018

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

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Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

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The IRS-signalling system during insulin and cytokine action

21 January 2018

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Hyperphosphorylation and increased proteolytic breakdown of c-Myb induced by the inhibition of Ser/Thr protein phosphatases

21 January 2018

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7 January 2021

JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation

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7 January 2021

A conformational change in the beta-subunit of the insulin-like growth factor I receptor identified by antipeptide antibodies

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7 January 2021

Selective activation of phospholipase C gamma1 and distinct protein kinase C subspecies in intracellular signaling by hepatocyte growth factor/scatter factor in primary cultured rat neocortical cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

Tyrosine Phosphorylation of Phospholipase Cγ in c-met/HGF Receptor-Stimulated Hepatocytes: Comparison with HepG2 Hepatocarcinoma Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

The platelet-derived growth factor receptor stimulation of p42/p44 mitogen-activated protein kinase in airway smooth muscle involves a G-protein-mediated tyrosine phosphorylation of Gab1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

The MAPK signaling cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

Protein phosphatase inhibitors arrest cell cycle and reduce branching morphogenesis in fetal rat lung cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

Loss of protein kinase C function induces an apoptotic response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204047

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313945%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 November 2019

1016972674

0 references

1 reference