Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development (Q24317761)

Hongwu Zheng

7

0 references

Frank B Furnari

Frank Furnari

9

0 references

Cameron Brennan

Cameron Brennan

2

0 references

P. Andrew Futreal

17

P Andrew Futreal

0 references

Michael Stratton

15

Michael R Stratton

0 references

William C Hahn

11

William C Hahn

0 references

Ruprecht Wiedemeyer

1

Ruprecht Wiedemeyer

0 references

Alexei Protopopov

6

Alexei Protopopov

0 references

author name string

Timothy P Heffernan

3

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Yonghong Xiao

4

0 references

John Mahoney

5

0 references

Graham Bignell

8

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Webster K Cavenee

10

0 references

Koichi Ichimura

12

0 references

V Peter Collins

13

0 references

Gerald C Chu

14

0 references

Keith L Ligon

Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma

16

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language of work or name

English

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publication date

April 2008

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published in

Cancer Cell

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volume

13

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issue

4

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page(s)

355-64

0 references

cites work

1 reference

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19 March 2017

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

19 March 2017

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

19 March 2017

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

19 March 2017

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Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1

19 March 2017

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

19 March 2017

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

19 March 2017

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

19 March 2017

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

7 April 2017

1 reference

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

7 April 2017

1 reference

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A comparison of DNA copy number profiling platforms

7 April 2017

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p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a

27 September 2017

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

27 September 2017

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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

27 September 2017

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Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment

27 September 2017

1 reference

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A faster circular binary segmentation algorithm for the analysis of array CGH data

27 September 2017

1 reference

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The regulation of INK4/ARF in cancer and aging

27 September 2017

1 reference

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High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances

27 September 2017

1 reference

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

27 September 2017

1 reference

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Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme.

27 September 2017

1 reference

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Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas

27 September 2017

1 reference

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Somatic mutations of the protein kinase gene family in human lung cancer

27 September 2017

1 reference

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Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data

27 September 2017

1 reference

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G1 cell-cycle control and cancer

27 September 2017

1 reference

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High-resolution characterization of the pancreatic adenocarcinoma genome

27 September 2017

1 reference

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Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review).

27 September 2017

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The RB and p53 pathways in cancer

27 September 2017

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

27 September 2017

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FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients

27 September 2017

1 reference

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The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

30 May 2018

1 reference

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Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.

29 November 2018

1 reference

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A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

Impact of DNA amplification on gene expression patterns in breast cancer

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292238

10.1016/J.CCR.2008.02.010

29 November 2018

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

18394558

1 reference