Oncogenic ERBB3 mutations in human cancers (Q24293022)

26 October 2023

22

Zora Modrusan

Zora

Modrusan

1 reference

26 October 2023

Mark A Merchant

28

Mark A

Merchant

1 reference

26 October 2023

Brock A Peters

18

Brock A

Peters

1 reference

26 October 2023

21

Michelle Mak

Michelle

Mak

1 reference

26 October 2023

Bijay S Jaiswal

1

Bijay S

Jaiswal

1 reference

26 October 2023

Noelyn M Kljavin

2

Noelyn M

Kljavin

1 reference

26 October 2023

Eric W Stawiski

3

Eric W

Stawiski

1 reference

26 October 2023

Emily Chan

4

Emily

Chan

1 reference

26 October 2023

Chaitali Parikh

5

Chaitali

Parikh

1 reference

26 October 2023

Steffen Durinck

6

Steffen

Durinck

1 reference

26 October 2023

Subhra Chaudhuri

7

Subhra

Chaudhuri

1 reference

26 October 2023

Kanan Pujara

8

Kanan

Pujara

1 reference

26 October 2023

Joseph Guillory

9

Joseph

Guillory

1 reference

26 October 2023

Kyle A Edgar

10

Kyle A

Edgar

1 reference

26 October 2023

Vasantharajan Janakiraman

11

Vasantharajan

Janakiraman

1 reference

26 October 2023

Rolf-Peter Scholz

12

Rolf-Peter

Scholz

1 reference

26 October 2023

Krista K Bowman

13

Krista K

Bowman

1 reference

26 October 2023

Maria Lorenzo

14

Maria

Lorenzo

1 reference

26 October 2023

Hong Li

15

Hong

Li

1 reference

26 October 2023

Jiansheng Wu

16

Jiansheng

Wu

1 reference

26 October 2023

Wenlin Yuan

17

Wenlin

Yuan

1 reference

26 October 2023

Zhengyan Kan

19

Zhengyan

Kan

1 reference

26 October 2023

Jeremy Stinson

20

Jeremy

Stinson

1 reference

26 October 2023

Ron Firestein

24

Ron

Firestein

1 reference

26 October 2023

Howard M Stern

25

Howard M

Stern

1 reference

26 October 2023

Krishnaraj Rajalingam

26

Krishnaraj

Rajalingam

1 reference

26 October 2023

Gabriele Schaefer

27

Gabriele

Schaefer

1 reference

26 October 2023

Mark X Sliwkowski

29

Mark X

Sliwkowski

1 reference

26 October 2023

Frederic J de Sauvage

30

Frederic J

de Sauvage

1 reference

26 October 2023

Somasekar Seshagiri

31

Somasekar

Seshagiri

1 reference

ERBB3 kinase domain mutations are rare in lung, breast and colon carcinomas

26 October 2023

language of work or name

English

0 references

publication date

13 May 2013

0 references

published in

Cancer Cell

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volume

23

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issue

5

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page(s)

603-17

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cites work

1 reference

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The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

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The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

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An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

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7 January 2021

The ERBB3 receptor in cancer and cancer gene therapy

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7 January 2021

Patterns of somatic mutation in human cancer genomes

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7 January 2021

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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Somatic mutations affect key pathways in lung adenocarcinoma

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ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor

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Diverse somatic mutation patterns and pathway alterations in human cancers

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Integrated genomic analyses of ovarian carcinoma

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7 January 2021

Systematic identification of genomic markers of drug sensitivity in cancer cells

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7 January 2021

The landscape of cancer genes and mutational processes in breast cancer

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7 January 2021

Comprehensive molecular characterization of human colon and rectal cancer

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7 January 2021

Recurrent R-spondin fusions in colon cancer

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7 January 2021

Comprehensive molecular portraits of human breast tumours

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7 January 2021

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

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7 January 2021

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

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7 January 2021

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

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7 January 2021

Direct observation of individual endogenous protein complexes in situ by proximity ligation

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7 January 2021

ERBB receptors and cancer: the complexity of targeted inhibitors

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7 January 2021

Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

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7 January 2021

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.

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7 January 2021

Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

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7 January 2021

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

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7 January 2021

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

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Structure of the extracellular region of HER3 reveals an interdomain tether

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Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

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7 January 2021

3D culture reveals a signaling network

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Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

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Theme: oncology--molecular mechanisms determining the efficacy of EGF receptor-specific tyrosine kinase inhibitors help to identify biomarker candidates

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7 January 2021