Statins for the prevention of dementia (Q24241335)

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object named as

Bernadette McGuinness

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author name string

David Craig

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Roger Bullock

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Peter Passmore

Cochrane Database of Systematic Reviews

4

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publication date

15 April 2009

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published in

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cites work

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Association between apolipoprotein E4 and cognitive decline in elderly adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Effects of lovastatin on cognitive function and psychological well-being

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Effect of pharmacologic lipid lowering on health-related quality of life in older persons: results from the Cholesterol Reduction in Seniors Program (CRISP) Pilot Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Removal of cholesterol from extrahepatic sources by oxidative mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Efficacy and tolerability of donepezil in vascular dementia: positive results of a 24-week, multicenter, international, randomized, placebo-controlled clinical trial

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The Alzheimer's disease beta-secretase enzyme, BACE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Paraoxonase 1 activity: a new vascular marker of dementia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Vascular factors in dementia: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: the Three-City Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Serum cholesterol and cognitive performance in the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Neuropathological assessment of the lesions of significance in vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The impact of the use of statins on the prevalence of dementia and the progression of cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Is there a connection between the concentration of cholesterol circulating in plasma and the rate of neuritic plaque formation in Alzheimer disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statin treatment alters serum n-3 and n-6 fatty acids in hypercholesterolemic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statins and the risk of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cognitive impairment associated with atorvastatin and simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Isoprenoids as mediators of the biological effects of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

APP processing enzymes (secretases) as therapeutic targets: insights from the use of transgenics (Tgs) and transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

CNS synaptogenesis promoted by glia-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statins for the treatment of Alzheimer's disease and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The role of cholesterol and statins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

High-density lipoprotein cholesterol in differential diagnosis of senile dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Serum Cholesterol and Intellectual Performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Serum Total Cholesterol, Apolipoprotein E {FC12}e4 Allele, and Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Enhanced oxidizability of ubiquinol and α‐tocopherol during lovastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Alzheimer's disease: cholesterol, membrane rafts, isoprenoids and statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Relation of plasma lipids to Alzheimer disease and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Use of lipid-lowering drugs in older adults with and without dementia: a community-based epidemiological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Plasma antioxidant activity and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol and Alzheimer's disease: is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Status of Risk Factors for Vascular Dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Circulating cholesterol levels, apolipoprotein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer's disease: results of the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Reduced risk of incident AD with elective statin use in a clinical trial cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Type 2 diabetes mellitus, cognitive impairment and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Association between high-density lipoprotein and cognitive impairment in the oldest old.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statin-associated memory loss: analysis of 60 case reports and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Subchronic toxicity of atorvastatin, a hydroxymethylglutaryl-coenzyme A reductase inhibitor, in beagle dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Donepezil in vascular dementia: a randomized, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Is Alzheimer's disease an apolipoprotein E amyloidosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Serum lipoprotein levels, statin use, and cognitive function in older women

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Lipoprotein profile in older patients with vascular dementia and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statins for the reduction of risk of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Statin Use and the Risk of Incident Dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

The design of a prospective study of pravastatin in the elderly at risk (PROSPER)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

Low-Density Lipoprotein Cholesterol and the Risk of Dementia With Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

New possible role of statins in age-related diseases

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

High-dose atorvastatin after stroke or transient ischemic attack

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Serum cholesterol concentrations are associated with visuomotor speed in men: findings from the third National Health and Nutrition Examination Survey, 1988-1994.

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Apolipoprotein E alleles and hyperlipoproteinemia in Japan

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Association between statin use and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Associations of lipoprotein cholesterols, apolipoproteins A-I and B, and triglycerides with carotid atherosclerosis and coronary heart disease. The Atherosclerosis Risk in Communities (ARIC) Study.

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

High-Density Lipoproteins Inhibit Cytokine-Induced Expression of Endothelial Cell Adhesion Molecules

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Statins, incident Alzheimer disease, change in cognitive function, and neuropathology

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD003160.PUB2

7 January 2021

10.1002/14651858.CD003160.PUB2

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

19370582

1 reference

Consolidated OpenCitations Corpus – April 2017