SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity (Q22009910)

PubMed

PubMed publication ID

10347175

7 February 2023

G A Koretzky

series ordinal

2

author given names

G A

author last names

Koretzky

1 reference

PubMed

PubMed publication ID

10347175

Journal of Biological Chemistry

7 February 2023

language of work or name

English

0 references

publication date

4 June 1999

0 references

published in

0 references

volume

274

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issue

23

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page(s)

16206-12

0 references

cites work

The regulation and function of p21ras during T-cell activation and growth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

T-cell activation: integration of signals from the antigen receptor and costimulatory molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

T cell differentiation: control by the pre-TCR and alpha beta TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

A functional T-cell receptor signaling pathway is required for p95vav activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Lck regulates Vav activation of members of the Rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Proto-vav and gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Mechanisms of transactivation by nuclear factor of activated T cells-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

The Yin and Yang of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Upstream-downstream: CD28 cosignaling pathways and T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Mechanism responsible for T-cell antigen receptor- and CD28- or interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Adaptor proteins in lymphocyte antigen-receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

The real LAT steps forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Cbl: complex formation and functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Vav links antigen-receptor signaling to the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206

inferred from DOI database lookup

7 January 2021

based on heuristic

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.23.16206