Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation (Q24329121)

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D G Motto

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G A Koretzky

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A Weiss

Proteins regulating Ras and its relatives

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language of work or name

English

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publication date

June 1996

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published in

Immunity

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volume

4

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issue

6

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page(s)

593-602

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cites work

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Proto-vav and gene expression.

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Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells

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Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

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7 January 2021

Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins

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7 January 2021

The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

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ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

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7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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7 January 2021

Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck

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Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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The proto-oncogene Vav product is constitutively tyrosine-phosphorylated in normal human immature T cells

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7 January 2021

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

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7 January 2021

Signal transduction in T lymphocytes using a conditional allele of Sos

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Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells

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7 January 2021

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

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7 January 2021

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

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7 January 2021

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

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7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

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7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

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7 January 2021

Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL

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7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

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7 January 2021

p95vav associates with the nuclear protein Ku-70

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7 January 2021

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

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7 January 2021

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

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7 January 2021

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

A functional T-cell receptor signaling pathway is required for p95vav activity

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7 January 2021

Binding of Vav to Grb2 through dimerization of Src homology 3 domains

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7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

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7 January 2021

The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro.

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7 January 2021