Ubiquitin conjugating enzyme E2 D1 (Q21120023)

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mammalian protein found in Homo sapiens
  • stimulator of Fe transport
  • (E3-independent) E2 ubiquitin-conjugating enzyme D1
  • ubiquitin-conjugating enzyme E2(17)KB 1
  • ubiquitin conjugating enzyme E2D 1
  • UbcH5
  • ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
  • E2 ubiquitin-conjugating enzyme D1
  • ubiquitin-protein ligase D1
  • ubiquitin carrier protein D1
  • ubiquitin-conjugating enzyme E2 D1
  • ubiquitin-conjugating enzyme E2-17 kDa 1
  • 2.3.2.24
  • UBC4/5 homolog
  • UBE2D1
  • SFT
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Language Label Description Also known as
English
Ubiquitin conjugating enzyme E2 D1
mammalian protein found in Homo sapiens
  • stimulator of Fe transport
  • (E3-independent) E2 ubiquitin-conjugating enzyme D1
  • ubiquitin-conjugating enzyme E2(17)KB 1
  • ubiquitin conjugating enzyme E2D 1
  • UbcH5
  • ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
  • E2 ubiquitin-conjugating enzyme D1
  • ubiquitin-protein ligase D1
  • ubiquitin carrier protein D1
  • ubiquitin-conjugating enzyme E2 D1
  • ubiquitin-conjugating enzyme E2-17 kDa 1
  • 2.3.2.24
  • UBC4/5 homolog
  • UBE2D1
  • SFT

Statements

molecular function
ubiquitin conjugating enzyme activity
determination method or standard
IDA
IEA
6 references
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IEA
retrieved
24 April 2018
stated in
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
24 April 2018
stated in
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
24 April 2018
stated in
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
24 April 2018
stated in
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
24 April 2018
stated in
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51668&geneProductId=UniProtKB:P51668
determination method or standard
IDA
protein binding
determination method or standard
IPI
12 references
retrieved
8 April 2019
stated in
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
GOA
curator
UniProt
UniProt protein ID
P51668
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis
GOA
curator
UniProt
UniProt protein ID
P51668
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mechanism of ubiquitylation by dimeric RING ligase RNF4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IPI
ubiquitin conjugating enzyme activity
determination method or standard
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IEA
retrieved
8 April 2019
stated in
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
8 April 2019
stated in
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
8 April 2019
stated in
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
8 April 2019
stated in
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
8 April 2019
stated in
Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51668
determination method or standard
IBA
cell component
biological process

Identifiers

 
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