The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance (Q24293991)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

Ubiquitin conjugating enzyme E2 D1

9 January 2020

main subject

1 reference

F-box protein 4

1 reference

telomeric repeat binding factor 1

1 reference

positive regulation of telomere maintenance via telomerase

1 reference

author

Jeffrey W. Harper

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Tae Ho Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kilian Perrem

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kun Ping Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Xiao Zhen Zhou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

7 November 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

759-768

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

Switching and signaling at the telomere

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Telomeres and telomerase: implications for cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Connecting chromosomes, crisis, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Telomeres, aging and cancer: in search of a happy ending

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Role of Pin2/TRF1 in telomere maintenance and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Regulation of telomerase by telomeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

PTOP interacts with POT1 and regulates its localization to telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Control of telomere length by the human telomeric protein TRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

TIN2, a new regulator of telomere length in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Control of human telomere length by TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

TRF1 is a critical trans-acting factor required for de novo telomere formation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A human peptidyl-prolyl isomerase essential for regulation of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Organization and expression of human telomere repeat binding factor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A human telomeric protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Targeted deletion reveals an essential function for the telomere length regulator Trf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Systematic analysis and nomenclature of mammalian F-box proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

The SCF ubiquitin ligase: insights into a molecular machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A resource for large-scale RNA-interference-based screens in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A family of mammalian F-box proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Identification of a family of human F-box proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Nuclear speckle localisation of the small heat shock protein alpha B-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Human POT1 facilitates telomere elongation by telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Identification of yeast mutants with altered telomere structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Generation of telomere-length heterogeneity in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Tankyrase promotes telomere elongation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

21 January 2018

2 references

https://api.crossref.org/works/10.1074%2FJBC.M509855200

21 January 2018

https://api.crossref.org/works/10.1074%2FJBC.M509855200

7 January 2021

CDC17: an essential gene that prevents telomere elongation in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

7 January 2021

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

7 January 2021

The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509855200

7 January 2021

Identifiers

DOI

10.1074/JBC.M509855200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16275645%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017