Ygyktvu7d MEIOSIS

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CELLULAR

REPRODUCTION
Prepared by: Ms. Ma. Filipina Q. Apid, LPT
LET’S RECAP

METAPHASE CYTOKINESIS TELOPHASE

ANAPHASE PROPHASE
LET’S RECAP

PROPHASE METAPHASE ANAPHASE

TELOPHASE CYTOKINESIS
MEIOSIS
Meiosis
• The form of cell division by which gametes, with half the
number of chromosomes, are produced.

• Diploid (2n)  haploid (n)

• Meiosis is sexual reproduction.

• Two divisions (meiosis I and meiosis II).


Fertilization
• The fusion of a sperm and egg to form a zygote.
• A zygote is a fertilized egg

sperm
n=23 n=23
egg
2n=46
zygote
Meiosis
• Sex cells divide to produce gametes (sperm or egg).
• Gametes have half the # of chromosomes.
• Occurs only in gonads (testes or ovaries).

Male: spermatogenesis
Female: oogenesis
• Meiosis is similar to mitosis with some chromosomal differences.
Interphase I
• Similar to mitosis interphase.
• Chromosomes replicate (S phase).
• Each duplicated chromosome consist of two identical sister
chromatids attached at their centromeres.
• Centriole pairs also replicate.
Interphase I • Nucleus and nucleolus visible.

chromatin nuclear
membrane

cell membrane

nucleolus
Meiosis I (four phases)
• Cell division that reduces the chromosome number by one-half.

FOUR PHASES:
a. prophase I
b. metaphase I
c. anaphase I
d. telophase I
Prophase I
• Longest and most complex phase (90%).

• Chromosomes condense.

• Synapsis occurs: homologous chromosomes come together to form a tetrad.

• Tetrad is two chromosomes or four chromatids (sister and nonsister chromatids).


Prophase I - Synapsis
Homologous chromosomes

sister chromatids sister chromatids


Tetrad
Homologous Chromosomes
• Pair of chromosomes (maternal and paternal) that are similar in shape
and size.
• Homologous pairs (tetrads) carry genes controlling the same inherited
traits.
• Humans have 23 pairs of homologous chromosomes.
a. 22 pairs of autosomes
b. 01 pair of sex chromosomes
Karyotype
• A method of organizing the chromosomes of a cell in relation to number, size, and
type.
Autosomes
(The Autosomes code for most of the offspring’s traits)

In Humans the
“Autosomes”
are sets 1 - 22
During Prophase I
“Crossing Over” occurs.

(Crossing Over is one of the Two major occurrences of Meiosis


The other is Non-disjunction)

• During Crossing over segments of nonsister chromatids break


and reattach to the other chromatid. The Chiasmata (chiasma)
are the sites of crossing over.
Crossing Over
creates variation (diversity) in the offspring’s traits.

nonsister chromatids Tetrad

chiasmata: site of variation


crossing over
Another Way Meiosis Makes Lots of
Different Sex Cells – Crossing-Over
Prophase I

spindle fiber centrioles

aster
fibers
Metaphase I
• Shortest phase

• Tetrads align on the metaphase plate.

metaphase plate
Anaphase I
• Homologous chromosomes separate
and move towards the poles.

• Sister chromatids remain attached at


their centromeres.
Telophase I
• Each pole now has haploid
set of chromosomes.

• Cytokinesis occurs and two


haploid daughter cells are
formed.
Meiosis II

• No interphase II
(or very short - no more DNA replication)
• Remember: Meiosis II is similar to mitosis
Prophase II
• same as prophase in mitosis
Metaphase II
• same as metaphase in mitosis

metaphase plate metaphase plate


Anaphase II
• same as anaphase in mitosis
• sister chromatids separate
Telophase II
• Same as telophase in mitosis.
• Nuclei form.
• Cytokinesis occurs.
• Remember: four haploid daughter
cells produced.
gametes = sperm or egg
Meiosis
n=2

sex cell sperm


n=2
n=2

2n=4
haploid (n)
n=2
diploid (2n) n=2

n=2
meiosis I
meiosis II
LET’S RECAP!

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