Amblyopia

AMBLYOPIA Classification
and Maanagment
Hifza Imtiaz
A.P DOVS
Amblyopia
Amblyopia is a condition of diminished visual form
sense which is not as a result of any clinically
demonstrable anomaly of the visual pathway and
which is not relieved by the elimination of any defect
that constitutes a dioptric obstacle to the formation
of the foveal image.
It occurs in up to 2 to 4% of the population
Aetiology
Amblyopia is caused by inadequate stimulation of the
visual system during the critical period of visual
development in early childhood
Light deprivation
Form deprivation
Abnormal binocular interaction
The prognosis for achieving good visual acuity decreases when more than
one of these factors is present together in one case.
Amblyopia Classification
Stimulus deprivation amblyopia
Strabismic amblyopia
Anisometropic amblyopia
Meridional amblyopia
Ametropic amblyopia
Occlusion amblyopia
Stimulus deprivation amblyopia:
Amblyopia, which is the result of lack of adequate
visual stimulus in early life. This may be unilateral or
bilateral and may be:
– complete, where no light enters the eye
– partial, where there is some passage of light into the
eye.
Strabismic amblyopia:
Amblyopia, which is the result of manifest strabismus
and is caused by constant unilateral strabismus in
childhood.
Anisometropic amblyopia:
Amblyopia, which is the result of a significant
difference in the refractive errors of the two eyes
where one eye has the visual advantage at all
distances.
Meridional amblyopia:
Amblyopia, which is the result of uncorrected astigmatism
where one or both eyes are predominantly astigmatic.
 Ametropic amblyopia:
Bilateral amblyopia, which is the result of a high degree
of uncorrected bilateral refractive error.
 Occlusion amblyopia:
Amblyopia, which may occur after use of total occlusion
or atropine, particularly before the age of 2 years. Visual
acuity is usually restored with careful treatment and
monitoring
Investigation
Refraction
Case history
Visual acuity
Contrast sensitivity
Cover test
Visuscope
A modified ophthalmoscope containing a
small graticule target for the measurement of
eccentric fixation.
Management
Correct the refractive error as visual acuity often
responds when the correct prescription is worn
(refractive adaptation).
 A period of 6 to18 weeks is recommended for
refractive adaptation before implementation of
occlusion
Methods of treatment to restore visual
acuity in amblyopia
Occlusion
Cycloplegic
Drugs
Optical penalization
CAM visual stimulator
Management
Occlusion is the most commonly used method
of treating amblyopia.
The normal eye is occluded and occlusion may
be in the form of total light or form, or partial.
Management
Total light and form: Skin patches etc
 Total form: Frosted glasses etc
 Partial: Semi transparent material
which reduced VA up to some extent
Duration of occlusion
• The starting level of occlusion is between 2 and 6 hours
daily coupled with near or distance activities.
• Two hours of occlusion daily has been shown to be as
effective
as 6 hours daily for amblyopia of 0.3–0.6 logMAR in
children under the age of7 years.
• For those with amblyopia of 0.7–1.3, 6 hours of occlusion
is as effective as full-time.
Duration of occlusion
An ideal goal is less than 400 hours of occlusion or 6
months of occlusion treatment.
Late occlusion (after the age of 8 years) has been shown
to be effective in selected cases.
Consequences of amblyopia
The risk of permanent visual loss in the better eye is
reported as 32.9 per 100,000population .
Presence of amblyopia interferes with schooling, work,
lifestyle, sports and career choice.
Aims of occlusion
1. Equalize visual acuity

2. Achieve optimum visual acuity
3. Central fixation
Continue occlusion until:
1. equal visual acuity is achieved;
2. the optimum visual acuity is achieved;
3. there is no further increase in visual acuity with full-time
total occlusion.
Recurrence
Long-term follow-up of amblyopic patients shows an
average reduction in visual acuity for up to 75% of
patients of 1.2–2.6 Snellen lines at least 5 years post
cessation of treatment (Gregersen & Rindziunski 1965, Sparrow &
Flynn 1979,PEDIG 2004, Bhola et al. 2006, King et al. 2007, De Weger et al.
2010)ss
Compliance issues
• Success of occlusion treatment relates in part to the
compliance of the patient and parents/guardian in
undertaking the occlusion regime.
• It is generally agreed that thorough discussion of the
occlusion regime backed up by written information has a
positive impact on occlusion success (Newsham 2002).
• Compliance has been reported in 78% in those with
written information and 57% in those without
information (Loudon et al. 2006).
•
Unresponsive amblyopia
• Where visual acuity does not improve with occlusion
treatment, an increase in occlusion or switch to
another treatment option should be considered.
Where continued lack of improvement occurs,
detailed assessment of the visual pathway should be
made to exclude pathology.
Cycloplegic drugs
Where occlusion is not tolerated, cycloplegic drugs may
be used to blur the vision in the better eye, thereby giving
the amblyopic eye more stimulus.
Typically, atropine 1% has been used once daily but
atropine instilled only at weekends is equally effective
(PEDIG 2004, Repka et al. 2009).
 Atropine has been shown to be equally as effective as
occlusion for visual acuity of 0.3–0.7 logMAR (PEDIG 2002)
with maintenance of visual acuity to long-term follow-up
(PEDIG 2008).
Cycloplegic drugs
Advantages
1. The patient cannot cheat as can occur with occlusion where the
child peeps over the patch or where there is poor or non-
compliance.
2. The child and parent often prefer it to occlusion.
3. There is little or no cosmetic problem.
Disadvantages
1. Side effects of atropine.
2. Visual acuity may not be reduced enough where there is dense
amblyopia.
3. Atropine takes a period of 10–14 days to wear off.
4. Frequent visits are required to monitor fixation as an indicator of
visual acuity.
Penalisation
Penalisation is the treatment of amblyopia by optical
reduction of form vision of the nonamblyopic eye at one
or all fixation distances.
The effect may be achieved by the alteration of the
spectacle correction or use of a cycloplegic drug
(Gregersen et al. 1965, Repka & Ray 1993).
Drugs
Dopamine is a neurotransmitter which is involved
in several visual functions.
Levodopa given orally produces an increase in contrast
sensitivity in an amblyopic eye but does not induce
changes in the non amblyopic eye (Gottlob & Stangler -
Zuschrott 1990).
These findings suggest an involvement of dopaminergic
function in amblyopia, and support the association
between amblyopia and neurotransmitters reported in
the literature.
Risks of occlusion
Intractable diplopia
Occlusion amblyopia.
Dissociation of latent/intermittent deviation.
Allergic response.
 Danger socially due to disorientation.
Latent nystagmus (become manifist)
THANK YOU

Amblyopia

Uploaded by

Copyright:

Available Formats

Amblyopia

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Amblyopia

Uploaded by

Copyright:

Available Formats

AMBLYOPIA Classification

1. Equalize visual acuity

You might also like