Penilaian Status Gizi Secara Biokimia: Dr. Ety Yuni Ristanti, SKM, MPH

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PENILAIAN STATUS

GIZI SECARA
BIOKIMIA

Dr. Ety Yuni Ristanti, SKM, MPH

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PENILAIAN STATUS
GIZI ANEMIA GIZI
Secara Biokimia

INDIKATOR
Hb, Hematokrit, Serum Besi, Serum
Ferritin, Transferin Saturation, FEP

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HEMOGLOBIN (Hb)

Pemeriksaan Hb dpt tentukan prevalensi Anemia

01 A. METODE SAHLI
- Kesalahan 2 – 3 kali
- Hb + Hcl ➔ Globin Fe ++ Heme ➔ O2
02
➔ Fe +++ Heme + Ion cl ➔ Ferri
Hemeclorid (coklat)

03

04
B. METODE CYANMETHEMEGLOBIN
- Hb Oksidasi K. Peroksida ➔
Methemoglobin ➔ Ion Sianida ➔
Sian – Methemoglobin (merah)
- Hasil lbh obyektif

 NILAI NORMAL
- Laki – Laki : 14 – 18 gr %
- Wanita : 12 – 16 gr %
- Wanita Hamil : 11 gr %

AWESOME
SLIDE
HEMATOKRIT (HCT)

-Volume SDM yg terpisah dr plasma


- Estimasi scr tdk langsung Hb (HCT
3 X Hb)

 HARGA NORMAL
- Laki – laki : 40 – 54 % Kepler
- Wanita : 37 – 47 %
- laki – laki : 42 – 50 % Wells
- Wanita : 40 – 48 %
FREE ERYTHROCYTE
SERUM FERRITIN TRANSFERIN PROTOPHORPHYRIN
(SF) SATURATION (TS) (FEP)
Content Here

- Menilai kecukupan Fe utk


- Menilai status besi - Menilai kadar Fe pembtk SDM di SSM
di hepar dlm serum Tulang
- SF < 12 µg /L - TS < 16 %
(Defisiensi Fe) (Defisiensi Fe) - Normal : 35 – 50 µg/dl RBC
- Metode : IRMA, - TIBC tinggi - FEP > 100 µg/dl ( Defisiensi
RIA, ELLISA (Anemia Gizi Fe)
. Besi) - Metode : Flurometic
PSG BIOKIMIA KEP
ANALISIS BIOKIMIA YG DIGUNAKAN
Nilai Protein & Hasil Metabolit
Protein (Darah, Urine)

INDIKATOR
- Rasio As Amino Bebas (Plasma)
- Plasma Protein, Albumin, Prealbumin
- Plasma Transferin
HARGA NORMAL
- Albumin : 3,5 – 5 gr/dl
- Globulin : 1,5 – 3 gr/dl
- Fibrinogen : 0,2 – 0,8 gr/dl
PRE – ALBUMIN
- Gizi Baik : 23,8 ± 0,9 mg/dl
- Gizi Sedang : 16,5 ± 0,8 mg/dl
- Gizi Kurang: 12,4 ± 1,0 mg/dl
- Marasmus : 7,6 ± 0,6 mg/dl
- Mars – Kwas : 3,3 ± 0,2 mg/dl
- Kwashiorkor : 3,2 ± 0,4 mg/dl
SERUM ALBUMIN
- < 1 Th : Cukup > 2,5 gr/dl
- 1 sd 5 Th : Cukup > 3 gr/dl
- 6 sd 16 Th : Cukup > 3,5 gr/dl
- 16 Th
Cukup : > 3,5 gr/dl
Kurang : < 2,8 gr/dl
Margin: 2,8 – 3,4 gr/dl
- Wanita Hamil
Cukup : > 3,5 gr/dl
Kurang : < 3,5 gr/dl
Margin : 3 – 3,4 gr/dl
SERUM PROTEIN
- < 1 Th : Cukup > 5 gr/dl
Margin < 5 gr/dl
- 1 sd 5 Th : Cukup 5,5 gr/dl
Margin < 5,5 gr/dl
- 6 sd 16 Th : Cukup 6 gr/dl
Margin < 6 gr/dl
- > 16 Th : Cukup 6 gr/dl
Kurang 5,5 gr/dl Margin 6,5 – 5,9 gr/dl

INDIKATOR KEP
Abumin/Globulin, Kolest & Hb turun
PSG BIOKIMIA KVA
 PROSES
Cadangan Vit A Hepar << ➔
Deplesi Vit A dlm tbh ➔ Kadar Vit A
plasma turun ➔ Disfungsi Retina ➔
perubahan epitel
 INDIKATOR
1. Vit A Plasma Normal : ≥ 30 µg/dl
KVA : < 5 µg/dl
2. Vit A Hepar Normal : ≥ 15 µg/dl
KVA : <15 µg/dl
3. RBP Normal : ≥ 20 µg/dl
KVA : < 20 µg/dl
PSG BIOKIMIA GAKI
 INDIKATOR
1. Ekskresi Iodium dlm Urine
- N > 50 µg/gr Creatinin
- Endemis Sedang : 25 - 50 µg/gr
Creatinin
- Endemis Berat : < 25 µg/gr
Creatinin
2. TSH
- N : 0,5 – 4,7 µg/ml
THANK YOU
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