Food Allergens: By: Suraj Kamath Reg. No. Nu20Ahfb14

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FOOD

ALLERGENS

BY: SURAJ KAMATH


REG. NO. NU20AHFB14
WHAT IS FOOD ALLERGIES?

• A food allergy is an exaggerated immune response triggered by


eggs, peanuts, milk, or some other specific food.
• Food allergy is an abnormal response to a food triggered by the
body's immune system.
• Allergic reactions to food can cause serious illness or even
death.
WHAT IS FOOD INTOLERANCE ?

• An abnormal physiological response to eating Food intolerance


is caused by the lack of our body’s ability to digest certain
substances.
• Some people may have a food intolerance that has a
psychological trigger.
• Food allergy is different with food intolerance although both
can show similar symptoms.
FOOD INTOLERANCE
• Food poisoning:
• Histamine toxicity
• Lactose intolerance
• Food additives, such as:-
• MSG
• Sulfites
WHAT IS HISTAMINE INTOLERANCE?

Histamine is a chemical our bodies produce naturally, and it's also found in
certain foods.
Histamine is a chemical responsible for a few major functions:
 Communicates messages to your brain
 Triggers release of stomach acid to help digestion
 Releases after injury or allergic reaction as part of your immune response
SYMPTOMS OF HISTAMINE
INTOLERANCE

Histamine is associated with common allergic responses and symptoms. Many of these
are similar to those from a histamine intolerance.
While they may vary, some common reactions associated with this intolerance include:
 Headaches or Migraines
 Nasal congestion or Sinus issues
 Digestive issues
 Irregular menstrual cycle
 Vomiting
HOW DO ALLERGIC REACTIONS WORK?
An immediate allergic reaction involves two actions of our immune system:
• Our immune system produces immunoglobulin E (IgE) -a type of protein that works
against a specific food - antibody.
• IgE attaches basophils (white blood cells) and to mast cells - cells found in all body
tissues. The typical sites of allergic reactions include nose, throat, lungs, skin
• Food allergens are proteins within the food that enter our bloodstream after the food is
digested.
• Food allergen go to target organs such as skin, nose, etc and cause allergic reactions.
• An allergic reaction to food can take place within few minutes to an hour.
TYPES OF ALLERGENS

 Inhalant Allergens: substances that are distributed in the atmosphere and


contact the nasal during respiration are called inhalant allergens.
 Ingestant Allergens: Those that occur in the food stuff and are swallowed
are known as ingestant.
 Injectants Allergens: Those may be present in the solutions intended for
parenteral administration are known as injectants.
FOOD ALLERGY TESTS

Diagnosis of allergy is based on a combination of:


 Clinical history.
 Skin tests

Identifying the type of IgE that is fixed to the skin mast cell. For example: scratch test.
 Blood tests → analyze CBC, TFT, GRBS and Urine R/E

RAST (radio allegrosorbent test) or ELISA ( enzyme-linked immunosorbent assay).


These tests measure the presence of food-specific IgE in blood and the total IgE level
in blood.
SKIN TESTS

Skin tests are conducted in 2 principal ways


• 1. Scratch test: It is similar to smallpox vaccination, i.e., scratching the skin
and introduce an extract of the allergic substances.
• 2. Intradermal (intra-cutaneous) tests: In which a small quantity of the extract
is injected between the layers of the skin.
IMMUNOTHERAPY OR HYPOSENSITIZATION TREATMENT

 It is a type of treatment in which the allergist suggests a serious of injections of


offending allergens.
 These injections are known as allergy shot. They are injected at regular intervals.
For safety reasons, the injections begins with small allergens dose, the amount of
allergens increased weekly, until a high dose of injected allergens are reached.

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