Polycystic kidney disease is an inherited disorder where clusters of cysts develop within the kidneys, causing them to enlarge and lose function over time. There are two main types: infantile type, an autosomal recessive disease presenting with cysts at birth and leading to renal failure; and adult type, an autosomal dominant disease presenting later in life with high blood pressure, pain, and cysts visible on imaging tests. Treatment focuses on controlling blood pressure to prevent further kidney damage, treating infections, and managing symptoms, with dialysis or transplant needed if kidney function is lost.
Polycystic kidney disease is an inherited disorder where clusters of cysts develop within the kidneys, causing them to enlarge and lose function over time. There are two main types: infantile type, an autosomal recessive disease presenting with cysts at birth and leading to renal failure; and adult type, an autosomal dominant disease presenting later in life with high blood pressure, pain, and cysts visible on imaging tests. Treatment focuses on controlling blood pressure to prevent further kidney damage, treating infections, and managing symptoms, with dialysis or transplant needed if kidney function is lost.
Polycystic kidney disease is an inherited disorder where clusters of cysts develop within the kidneys, causing them to enlarge and lose function over time. There are two main types: infantile type, an autosomal recessive disease presenting with cysts at birth and leading to renal failure; and adult type, an autosomal dominant disease presenting later in life with high blood pressure, pain, and cysts visible on imaging tests. Treatment focuses on controlling blood pressure to prevent further kidney damage, treating infections, and managing symptoms, with dialysis or transplant needed if kidney function is lost.
Polycystic kidney disease is an inherited disorder where clusters of cysts develop within the kidneys, causing them to enlarge and lose function over time. There are two main types: infantile type, an autosomal recessive disease presenting with cysts at birth and leading to renal failure; and adult type, an autosomal dominant disease presenting later in life with high blood pressure, pain, and cysts visible on imaging tests. Treatment focuses on controlling blood pressure to prevent further kidney damage, treating infections, and managing symptoms, with dialysis or transplant needed if kidney function is lost.
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POLYCSTIC KIDNEY
Polycystic kidney disease (PKD) is an inherited disorder
in which clusters of cysts develop primarily within your kidneys, causing your kidneys to enlarge and lose function over time. Cysts are noncancerous round sacs containing fluid. The cysts vary in size, and they can grow very large. Having many cysts or large cysts can damage our kidneys. CAUSE Congenital Progersion dilation of some portion of the nephron, which can arise during the fetal development. TYPES 1. infantile type It is inherited autosomal recessive disease
In this condition multiple cyste formation present in
renal tissue. In newborn baby spongy palpable of the kidney.
It present with palpable bilateral nodular cystic masses
with hypertension and progressive renal failure. 2. Adult type. o It is an autosomal dominate disease
o In both kidney multiple cyst formation is present.
o It present with anemia, polyuria, hypertension and
bilateral palpable nodular renal masses with irregular
distribution. SYMPTOMS
High blood pressure
Back or side pain
Headache
A feeling of fullness in your abdomen
Increased size of your abdomen due to enlarged kidneys
Blood in your urine
Kidney stones
Kidney failure
Urinary tract or kidney infections
DIAGNOSIS EVALUTION History taking Physical examination
USG
CT Scan
MRI
IVP : intra venous pylogram ( x ray examination of
kideny, ureters, urinary bladder) Renal angiography. TREATMENT High blood pressure. Controlling high blood pressure can delay the progression of the disease and slow further kidney damage. Combining a low-sodium, low-fat diet that's moderate in protein and calorie content with not smoking, increasing exercise and reducing stress may help control high blood pressure. Manage the pain Bladder or kidney infections. Prompt treatment of infections with antibiotics is necessary to prevent kidney damage. Blood in the urine. You'll need to drink lots of fluids, preferably plain water, as soon as you notice blood in your urine to dilute the urine. Dilution might help prevent obstructive clots from forming in your urinary tract. Kidney failure. If your kidneys lose their ability to remove waste products and extra fluids from your blood, you'll eventually need either dialysis or a kidney transplant. Aneurysms. If you have polycystic kidney disease and a family history of ruptured brain (intracranial) aneurysms, your doctor may recommend regular screening for intracranial aneurysms.
(Oxford Medical Handbooks) Robert C. Tasker (Editor), Carlo L. Acerini (Editor), Edward Holloway (Editor), Asma Shah (Editor), Pete Lillitos (Editor) - Oxford Handbook of Paediatrics-Oxford University