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    Endocytosis: Reported By: Francois Gayleheart Bautista Angela Lapuz Miguel Troy Octina Ian Gabriel Roda

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    The document discusses endocytosis, which is a form of active transport where a cell transports molecules into itself by engulfing them. There are four main pathways of endocytosis: clathrin-mediated, caveolae-mediated, macropinocytosis, and phagocytosis. The document also describes the principal components of endocytosis including early endosomes, late endosomes, and lysosomes.

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    Endocytosis: Reported By: Francois Gayleheart Bautista Angela Lapuz Miguel Troy Octina Ian Gabriel Roda

    Uploaded by

    VivaMapwa
    16 views8 pages
    The document discusses endocytosis, which is a form of active transport where a cell transports molecules into itself by engulfing them. There are four main pathways of endocytosis: clathrin-mediated, caveolae-mediated, macropinocytosis, and phagocytosis. The document also describes the principal components of endocytosis including early endosomes, late endosomes, and lysosomes.

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    SHS STEM BIO 01

    Original Title

    Endocytosis

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    The document discusses endocytosis, which is a form of active transport where a cell transports molecules into itself by engulfing them. There are four main pathways of endocytosis: clathrin-mediated, caveolae-mediated, macropinocytosis, and phagocytosis. The document also describes the principal components of endocytosis including early endosomes, late endosomes, and lysosomes.

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    Public Domain
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    16 views8 pages

    Endocytosis: Reported By: Francois Gayleheart Bautista Angela Lapuz Miguel Troy Octina Ian Gabriel Roda

    Uploaded by

    VivaMapwa
    The document discusses endocytosis, which is a form of active transport where a cell transports molecules into itself by engulfing them. There are four main pathways of endocytosis: clathrin-mediated, caveolae-mediated, macropinocytosis, and phagocytosis. The document also describes the principal components of endocytosis including early endosomes, late endosomes, and lysosomes.

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    of 8

    ENDOCYTOSIS

    Reported By:
    Francois Gayleheart Bautista
    Angela Lapuz
    Miguel Troy Octina
    Ian Gabriel Roda
    What is Endocytosis?
     It is a form of active transport in which
    a cell transports molecules (such as proteins) into
    the cell (endo + cytosis) by engulfing them in
    an energy-using process.

    It is often used because most of its 


    chemical substances  that are important to them
    are large polar molecules that cannot pass
    through the hydrophobic plasma or 
    cell membrane by passive means.
    Illustration of the Endocytosis
    4 Pathways of Endocytosis
    Clathrin-mediated endocytosis is mediated by small
    (approx. 100 nm in diameter) vesicles that have a
    morphologically characteristic coat made up of a
    complex of proteins that are mainly associated with the
    cytosolic protein clathrin.

    Caveolae are the most common reported non-clathrin-


    coated plasma membrane buds, which exist on the
    surface of many, but not all cell types.
    Clathryn-mediated endocytosis
    Macropinocytosis, which usually occurs from highly
    ruffled regions of the plasma membrane, is the
    invagination of the cell membrane to form a pocket,
    which then pinches off into the cell to form a vesicle
    (0.5–5 µm in diameter) filled with a large volume of
    extracellular fluid and molecules within it (equivalent
    to ~100 CCVs).
    Phagocytosis is the process by which cells bind and
    internalize particulate matter larger than around
    0.75 µm in diameter, such as small-sized dust particles,
    cell debris, micro-organisms andapoptotic cells.
    Principle Components
    Early Endosomes: first station of the endocytic
    pathway. Early endosomes are often located in the
    periphery of the cell, and receive most types of vesicles
    coming from the cell surface.
    Late Endosomes:  receive internalized material en route
    to lysosomes, usually from early endosomes in the
    endocytic pathway, from trans-Golgi network (TGN) in
    the biosynthetic pathway, and from phagosomes in the
    phagocytic pathway.
    Lysosomes: the last compartment of the endocytic
    pathway.
    Additional Knowledge
    The major route for endocytosis in most cells, and the
    best-understood, is that mediated by the molecule 
    clathrin.
    Was proposed by De Duve in 1963.
    Endocytosis includes pinocytosis (cell drinking) and 
    phagocytosis (cell eating).

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