Scribd Logo
Upload

Welcome to Scribd!

  • 52 views

    Wa0000

    Uploaded by

    Farzana
    Bioinformatics involves the application of computing to biology. It deals with tasks like calculating data, finding patterns in data, and performing measurements using computer technology. Bioinformatics focuses on automating biological software and processing biological data in computer laboratories through tasks like data storage, retrieval, and manipulation. Computational biology also uses computing for biology but performs additional analysis like sequence alignment and gene prediction in wet and dry laboratories.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd

    Wa0000

    Uploaded by

    Farzana
    52 views9 pages
    Bioinformatics involves the application of computing to biology. It deals with tasks like calculating data, finding patterns in data, and performing measurements using computer technology. Bioinformatics focuses on automating biological software and processing biological data in computer laboratories through tasks like data storage, retrieval, and manipulation. Computational biology also uses computing for biology but performs additional analysis like sequence alignment and gene prediction in wet and dry laboratories.

    Original Description:

    Paper

    Original Title

    DOC-20190419-WA0000

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Bioinformatics involves the application of computing to biology. It deals with tasks like calculating data, finding patterns in data, and performing measurements using computer technology. Bioinformatics focuses on automating biological software and processing biological data in computer laboratories through tasks like data storage, retrieval, and manipulation. Computational biology also uses computing for biology but performs additional analysis like sequence alignment and gene prediction in wet and dry laboratories.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    52 views9 pages

    Wa0000

    Uploaded by

    Farzana
    Bioinformatics involves the application of computing to biology. It deals with tasks like calculating data, finding patterns in data, and performing measurements using computer technology. Bioinformatics focuses on automating biological software and processing biological data in computer laboratories through tasks like data storage, retrieval, and manipulation. Computational biology also uses computing for biology but performs additional analysis like sequence alignment and gene prediction in wet and dry laboratories.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 9

    Introduction to Bioinformatics

    Bioinformatics
    • Biologists doing stuff with computers?
    • What stuff can biologists do with computers?
    Well, there are plenty:
    – Calculation of data
    – Finding patterns and information from data
    – Performing measurements and so on.
    • Computer technology more related towards
    automation of software’s related to biological
    domains.
    Related concepts
    • Computational biology: Application of computing to biology (broad
    definition). Often used interchangeably with Bioinformatics

    • Biometry: The statistical analysis of biological data. Combination of


    biology with the area of statistics.

    • Biophysics: An interdisciplinary field which applies techniques from the


    physical sciences to understanding biological structure and function
    • Combination of biology with the field of physics and physical sciences.

    • Mathematical biology: It tackles biological problems, but the methods it


    uses to tackle them need not be numerical and need not be implemented
    in software or hardware. Combination of biology with mathematics.
    BI vs CB
    • Bioinformatics is a newly born and
    multidisciplinary domain that involves the major
    contribution of biological sciences, information
    sciences, and computer sciences.
    • In order to make it capable of biological data
    processing, data management and data modeling
    issues, the research efforts in bioinformatics
    domain overlap to the research efforts in
    computational biology.
    • In fact bioinformatics domain is entirely different
    from the domain of computational biology.
    BI vs CB
    • The domain of bioinformatics deals with biological
    data, to achieve the objectives of storage, retrieval and
    manipulation of biological data, in Computer
    Laboratory (Computer Lab) only.
    • On the other hand, computational biology tackles
    sequence alignment, genome assembly, prediction and
    finding new genes/Protein structures, the development
    of various tools and techniques for statistical analysis
    and curation of biological data in Wet Laboratory (Wet
    Lab) and to some extent Dry Laboratory (Dry Lab).
    Biological Data Acquisition,
    Processing and Analysis
    • Biological data acquisition, processing and
    analysis functions occure at three working
    phases/stages;
    – Wet Laboratory (Wet Lab)
    – Dry Laboratory (Dry Lab)
    – Computer Laboratory (Computer Lab)
    Wet Lab
    • A Wet Lab is the Laboratory where biologists
    perform their physical experiments by using
    different samples, chemicals, drugs and other
    materials.
    • In this lab, biologists gather data and information
    by holding experiments on the samples of living
    organisms or by directly examining the living
    organisms under certain precautionary measures.
    • This data that is gathered during experiment is
    referred to as the raw data (uncured data)
    Dry Lab
    • Biologists bring raw data to the dry lab. This
    uncured data is still in biological form; therefore it
    is further processed for future analysis.
    • The process of cleanliness of uncured data is
    termed as data curation and it is performed in dry
    lab by biologists and robots.
    • There are little chances of error due to the
    automatic instruments.
    • Dry Lab produces the data as output; it is in a
    purified form.
    Computer Lab
    • Purified data can be used by computer
    scientists/ bioinformaticians in Computer Lab
    for analysis and other computing purposes.
    • This type of experimental data also called as
    annotated data is very much costly.
    • The annotated data is used for the derivation
    of various kinds of structure and function
    annotation, sequence determining and other
    structure predictions

    You might also like