Lipoma Pathway: DR Rajayogeswaran DR Mike Bradley

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Lipoma pathway

Dr Rajayogeswaran
Dr Mike Bradley
 Clinical features are typical of a small
(<5cm) subcutaneous lipoma
 Soft lipomatous consistency,
 Smooth edges,
 No pain
 No recent growth

 Reassure and asked to return if there are


changes.
 Lipomatous tumours are common in the
trunk and extremity.
 The majority, particularly in subcutaneous
tissues, are simple lipomas or benign variants
(eg angiolipomas or fibrolipomas).

 Deep lipomatous tumours (under the deep


fascia) are most often inter- or intramuscular
lipomas or atypical lipomatous tumours
(ALTs).

 ALTs are indolent tumours with no capacity


for metastatic spread without de-
differentiation (a rare event). ALTs can be
large (more than 5cm) at presentation
 Tumours which are lipomatous and
subcutaneous on ultrasound are rarely
malignant or ALTs, even if there are
atypical features on ultrasound (eg
vascularity or thickened septae.
 Patients can be reassured and advised to
observe the mass for changes.
 If necessary, confirmed superficial
lipomatous tumours can be excised by a
non-specialist surgical team, preserving
the underlying muscle fascia.
 In the unlikely event that such a tumour
is malignant on histological examination,
re-excision including the deep fascia is
usually possible without detriment to long
term outcomes
 Patients with scans diagnostic of a benign
lipoma with typical* or atypical** ultrasound
features and which are subcutaneous,
painless and not growing can be referred
back to primary care for further
management.
 This could include excision by a non-specialist
team, observation with advice to patients, or
interval scan (for example after 6 months).
 It is reasonable, if there are ongoing
concerns, to refer larger tumours in this
category (>7cm) for non-urgent assessment
by a Sarcoma Service, although the risk of
malignancy is very low
 Patients with scans diagnostic of a benign
lipoma with typical* or atypical**
ultrasound features

◦ deep to fascia,
◦ painful or
◦ enlarging

 Investigated with an MRI scan first


 Referred to a Sarcoma Service for advice
on a non-urgent basis (non-cancer
referral). This may include review of the
imaging and/or the patient.
 In the less common situation that the
scan indicates
◦ A lipoma with significantly concerning
ultrasound features,
◦ Or a non-lipoma with indeterminate or
concerning ultrasound features, raising the
possibility of malignancy.

Urgent 2-week wait, suspected cancer,


referral to a sarcoma service is appropriate,
ideally with an urgent MRI if available.
 GUIDE FOR ULTRASOUND IMAGING OF LIPOMATOUS TUMOURS

 • Benign lipoma with typical ultrasound features*


 o Homogeneous mass
 o No or septal linear power Doppler flow
 o No or thin (<2mm) septa

 • Benign lipoma with atypical ultrasound features**


 o Lipoma but very thick septa (>2mm)
 o Nodular area(s) of oedema or fat necrosis in predominantly fatty lesion
 o Disorganised power Doppler flow in predominantly fatty lesion

 • Lipoma with concerning ultrasound features***


 o Nodular area of non-fat signal in a deep lipomatous mass

 • Non-lipoma with indeterminate or concerning ultrasound features****


 o Solid non lipomatous mass
 o Heterogeneous mass
 o Invasive margins
 o Disorganised power Doppler flow in solid heterogeneous lesion

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