Biopsy Risk: by Jehanne Calinga
Biopsy Risk: by Jehanne Calinga
Biopsy Risk: by Jehanne Calinga
By Jehanne Calinga
• There should be little risk of spread by a biopsy in which the cancerous lump is easily
and completely removed. This is possible with superficial skin cancers including
melanoma, lymphatic tumors, and small breast cancers. It is also unlikely that taking
a 2-3 mm bite out of a fungating or ulcerating cancer anywhere in the
gastrointestinal tract, respiratory tract, or bladder during endoscopic examinations,
the usual mode of biopsy, is going to increase spread. These cancers are already
subjected to significant trauma on a daily basis. Bits probably break off all the time
and cause the bleeding that is their most common symptom.
• Core and needle biopsies can occasionally implant cancer in the needle tract, but
cases where this is a significant problem are rare. Wherever possible, for example
after breast lump biopsy, care is taken to cut out the needle track when the patient
has further surgery. I know of no evidence that such biopsies can induce blood
stream spread, but it is a theoretical possibility. Fine needle aspiration cytology (FNA)
is less traumatic than the larger needles used for core biopsies and should be safer,
although the latter will provide more information about the cancer in some
situations.
• The main risks of serious spread will apply with incision biopsies, where a
chunk is cut out of a cancer that is too large to completely remove in a
simple diagnostic procedure and when a detailed diagnosis is required
before definitive treatment can be planned. This would apply mainly with
sarcomas—cancers of soft tissue and bone.
• The potential for blood stream spread is not yet known, but is
theoretically possible or even likely. However, the risks of going without a
diagnosis when effective treatment is available are much greater.
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