Digestive System in The Pediatric Age Group: 4 Session

Download as ppt, pdf, or txt
Download as ppt, pdf, or txt
You are on page 1of 23

Digestive System in the

Pediatric age group

4th session
Topics:
Meconium Ileus and Peritonitis

Acute Appendicitis

Necrotizing enterocolitis

Anus and rectum

Imperforate anus

Anal fissures

Pruritus ani

Rectal prolapse

Hemorrhoids
Meconium ileus
Impaction of meconium; associated with Cystic fibrosis:
absence of fetal pancreatic enzymes limits normal digestive
activities of the intestines meconium becomes viscid and
mucilaginous clings to intestinal wall inspissated and
impacted meconium fills intestinal canal (lower part of the
ileum) abdominal distention, vomiting

Diagnosis:

Palpation of doughy or cordlike mass of intestines

Xray: loops vary in width and not evenly filled with gas; with
contrast: bubbly, granular appearance

Genetic testing to r/o CF


Treatment:

Gastrografin enema (high osmolality 1,900mOsm/L) draws


fluid into the intestinal lumen (need to dilute with equal part of
water to prevent DHN and shock)

Laparotomy

Complication: meconium peritonitis (treat by elimination of


intestinal obstruction, drainage of peritoneal cavity)
Neonatal Necrotizing Enterocolitis
Most common life threatening emergency in the NB

Mucosal or transmural necrosis of the intestines

Cause: unclear; multifactorial

Distal ileum and proximal colon

Risk factor: prematurity

Pathophysiology: intestinal ischemia, enteral nutrition


(metabolic substrate), bacterial translocation

Agents: E. coli, Klebsiella, Clostridium perfringens, S. epidermidis,


astrovirus, norovirus, rotavirus)
Intestinal ischemia leads to loss of bowel integrity
inflammatory response development of necrotic
segment gas accumulates into the submucosa of the
bowel pneumatosis intestinalis necrosis to perforation,
peritonitis, sepsis and death
Onset: 2nd or 3rd week of life or late (3mos) in VLBW infants
Clinical manifestations: nonspecific: lethargy, temperature
instability, abdominal distention, gastric retention
Diagnosis: plain abdominal radiographs (ant-posterior cross
table lateral or lateral decubitus); hepatic UTZ portal
venous gas
Treatment: no definitive treatment

Cessation of feeding (NPO), NG decompression,


administration of IVF, blood cultures, start antibiotics

Surgery: Explorative laparotomy

Peritoneal drainage (cautiously considered but has


complications death or neurodev. Outcome)

Pot-op complications: wound dehiscence, stomal problems,


intestinal strictures, short bowel syndrome
Acute Appendicitis
Pathophysiology: bacterial invasion of appendiceal wall
Luminal obstruction increase intraluminal pressure from
bacterial proliferation and mucus secretion leads to
lymphatic and venous congestion and edema impaired
arterial perfusion ischemia , inflammation, necrosis
12-18 yrs. Old
Signs and symptoms: classic or atypical (absence of fever,
Rovsings / Psoas/ Obturator/Guarding) or variable; abdominal
pain, nausea and vomiting, low grade fever to severe
manifestations (24-48hrs. later); perforation (beyond 36-48 hrs.)
Localized abdominal tenderness single most reliable finding
(McBurneys)
Diagnostic findings
CBC, UA, C-reactive protein

Radiologic studies: Plain films, UTZ, CT scan (gold standard imaging


study)

Complications: wound infection and intraabdominal abscess

Treatment: Appendectomy; laparoscopic appendectomy; interval


appendectomy; antibiotics and interventional radiology (drainage)

Antibiotics: Cefoxitin (nonperforated); perforated (Ampicillin,


Gentamicin and Clindamycin or Metronidazole) or (Ceftriaxone,
metronidazole or Ticarcillin-clavulanate plus Gentamicin)

HIGH LEVEL OF SUSPICION + COLLECTIVE REVIEW OF LABS +


SURGICAL REFERRAL
Surgical conditions of the
Anus and Rectum
Anorectal Malformations
Defined by the relationship of the rectum to the sphincter
complex (mass of muscle fibers: puborectalis, levator ani,
internal and external sphincter and superficial external
sphincter)

1/3,000 live births

Concerns on bowel control, urinary and sexual function


Embryology of Anorectal
malformations
2nd week AOG hindgut forms as part of the primitive gut
Day 13 hindgut ventral diverticulum (allantoin or primitive
bladder) junction of the hindgut and allantoin become
the CLOACA (where genital, urinary and intestinal tubes
empty); covered by a cloacal membrane
7th week AOG urorectum septum descends and form
lateral ridges to divide the cloaca into ANTERIOR and
POSTERIOR
8TH week AOG Posterior portion OPENS (anal membrane)
Associated anomalies: VATERR and VACTERL
Imperforate Anus
Inspection of the perineum of the NB

Normal position of the anus: approx. halfway (0.5


ratio)between the coccyx and scrotum or
introitus

A. LOW lesion rectum has descended into the


sphincter complex

B. HIGH lesion rectum has not


LOW lesion associated with perineal fistula or if
no fistula, thisckened raphe or bucket handle
HIGH lesion associated with fistula (boys:
retrobulbaurethral, rectoprostaticurethral,
rectovesicular) (girls: rectovaginal fistula)
PERSISTENT CLOACA treatment is repositioning
the urethra, vagina and rectum; rewuire a
COLOSTOMY before repair
RECTAL ATRESIA features a normal anal canal
and anus; rectal temperature: obstruction 2 cm
above skin level: protective colostomy
Approach to patients with
Anorectal Malformations
Clues:

Failure to pass meconium

Perineal inspection

- Do prone cross table lateral films

Plain xray of the entire sacrum

Abdominal-pelvic UTZ and VCUG

Other anomalies: pass NGT (esophagus); 2-D-echo


Operative Repair
LOW lesion if < 1cm from the skin minor perineal
procedure or do simple perineal anoplasty
- dilatation with HEGAR DILATORS
- if with fistula: posterior approach of PENA ffed by post-op
dilation
HIGH lesions colostomy 1st then do PSARP (posterior sagittal
anorectoplasty) at 1 year old; close colostomy 6 wks later or
Laparoscopic technique
OUTCOME: ability to achieve rectal continence (low > high);
ACE or antegrade continence enema
Anal Fissures
Minor lacerations of the anal mucocutaneous junction

Unknown but usually due to forceful passage of a hard stool in <


1yr old infants

Inspection of perineal area skin tags (epithelialized


granulomatous tissue formed because of chronic inflammation)

Goal: ensure soft stool (avoid overstretching of anus)


dietary and behavioral modification
stool softeners (water intake and oral polyethylene glycolate)
surgical intervention not indicated or supported by scientific
evidence (internal and sphincterotomy or excision of the fissure)
Perineal Abscess and Fistula
Unknown etiology

Mixed aerobic (E. coli, K. pneumoniae, S. aureus) and anaerobic


(Bacteroides, Clostridium, Veillonella) or associated with IBD,
leukemia, immunocompromised states

Ssx: low grade fever, mild rectal pain, areas of perianal cellulitis

Treatment: self limiting condition conservative mgt; antibiotics


are not useful except for systemic illness

- extreme patient discomfort abscess is drained under LA;


Fistulotomy (unroofing or opening), Fistulectomy or placement of
SETON
Hemorrhoids
Does not occur in children and adolescent
Related to a diet deficient of fiber and poor hydration
If present in younger children: portal HPN
2 types: EXTERNAL below the dentate line; extreme pain and
itching due to acute thrombosis
INTERNAL above the dentate line; bleeding, prolapse and occ.
Incarceration
Treatment: conservative mgt (diet, avoid straining/prolonged
sitting) discomfort (hot SITZ baths, topical analgesics);
THROMBECTOMY excruciating pain;
rubber band ligation, open excision and use of transanal stapling
device (painful internal hemorrhoids)
Rectal Mucosal Prolapse
Exteriorization of rectal mucosa through the anus

PROCIDENTIA all layers of the rectal wall

Idiopathic; onset: 1-5 yrs (standing) resolves in 3-5yrs.

Other predisposing factors: intestinal parasite, malnutrition,


diarrhea, UC, pertussis, CF, chronic constipation,
meningocoele, Ehlers-Danlos syndrome

Occurs during defecation


Treatment: reduction of protrusion push it back into the
rectum, aided with warm compress

Conservative management: careful manual reduction


avoid excessive pushing during BM; use of laxatives or stool
softeners; treatment of intestinal parasites; surgical treatment
(insertion of a Theirsch wire or Altemeir perineal
rectosigmoidoscopy); others: sclerosing injections, linear
cauterization
Pruritus Ani
Enterobiasis - nocturnal perianal pruritus
(Mebendazole100mg/day/Albendazole
400mg/day/Pyrantel pamoate 11 mkd)

Cholestasis xanthomas (accumulation of cholesterol bile


acids (Urodeoxycholic acid 15mkd)

Liver disease

Opioid use
End of 4th session

You might also like