Hielscher Ultrasonics

High-Power Ultrasonic Devices

for Lab and Industry

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 Hielscher Ultrasonics– Your Expert for Ultrasonic Processes
Hielscher Ultrasonics is the top supplier for high Sono-Chemistry:
power ultrasound devices. Hielscher offers various Sonochemistry is the application of ultrasound
ultrasonic processors for the use in lab, bench-top to chemical reactions and processes. The
a n d i n d u st r y. I m p o r ta nt a p p l i cat i o n s a re mechanism causing sonochemical effects in
homogenizing, emulsifying, dispersing, de- liquids is the phenomenon of acoustic
agglomeration as well as the sonochemistry and cavitation.
sono-catalysis.
High power ultrasound
Ultrasonic Homogenizing:
• increases the reaction speed and reaction
Hielscher homogenizers are very efficient for the
output,
reduction of soft and hard particles. By intense
•provides a more efficient energy usage,
cavitational forces, ultrasound reduces small
• improves the performance of phase transfer
particles (solids or liquids) in a liquid to improve
catalysts or makes an avoidance of phase
uniformity and stability.
transfer catalysts possible,
Ultrasonic Emulsifying: • increases the reactivity of reagents or
Emulsions are dispersions of two or more immiscible catalysts,
liquids. Highly intensive ultrasound supplies the • offers sono-chemical means for switching of
power needed to disperse a liquid phase (dispersed the reaction pathway,
phase) in small droplets in a second phase • enables to use crude or technical agents,
(continuous phase). In the dispersing zone, imploding • and activates metals and solids.
cavitation bubbles cause intensive shock waves in
Sono-Catalysis:
the surrounding liquid and result in the formation of
Ultrasonication affects the catalyst reactivity
liquid jets of high liquid velocity. As ultrasonication
during catalysis by enhanced mass-transfer
can produce very small droplets of almost uniform
and energy input. In heterogeneous catalysis,
size in batch and production process, ultrasound is
where the catalyst is in a different phase to the
an effective methods to create stable emulsions and
reactants, ultrasonic dispersion increases the
even microemulsions.
surface area available to the reactants.
Ultrasonication contributes to heterogeneous
and homogeneous catalysis in many ways.
Cavitational erosion on particle surfaces
generates unpassivated, highly reactive
surfaces. Short-lived high temperatures and
pressures contribute to molecular
decomposition and increase the reactivity of
many chemical species. Ultrasonic irradiation
can be used in the preparation of catalysts,
Ultrasonic Dispersing & Deagglomeration: e.g. to produce aggregates of fine-size
The dispersing power of ultrasound is well-known particles.
and a reliable and efficient method to mix powders
into liquids. High power ultrasound grinds and
deagglomerates particles held together by attraction
forces of physical and chemical nature down to
micron and nano size and disperses the individual
particles fine and evenly in the liquid. Generally,
ultrasound produces very narrow particles size
distribution.

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UP50H – Compact Lab Homogenizer
www.hielscher.com/up50

Ultrasonic Lab
Device UP50H

UP50H - compact light-weight UP50H at stand ST1-16

ultrasonic device

Technical UP50H: Compact ultrasonic lab device (50W, 30kHz) for handheld and
Details stand-mounted operation, automatic frequency tuning, amplitude
adjustable from 20 to 100%, pulse adjustable from 0 to100%, dry running
protected, with 9-pin DSUB interface, light-weight, in portable case, IP40
grade, titanium horn
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Wet-milling, Emulsifying, Lysis & Cell Disintegration, Extraction,
Degassing, Sonochemistry

Advantages Performance: With 50 watts power, the UP50H is much more powerful
than an ultrasonic bath or tank.
Flexibility: For handheld or stand-mounted use, with various accessories
for optimal adaption to your process.
Quality: The UP50H device fullfills the highest quality standards. All
devices are designed, engineered and manufactured in Germany.

Items:
□ Ultrasonic Processor UP50H ○ 115 volts ○ 230 volts
□ Sonotrode MS3 (tip diameter 3mm)
□ Sonotrode MS7 (tip diameter 7mm)
□ Stand ST1-16
□ ST1-Clamp
□ PowerMeter PowMet ○ 115 volts ○ 230 volts

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UP100H – Compact Lab Ultrasonicator
www.hielscher.com/up100

Ultrasonic Lab
Device UP100H

UP100H am Stativ ST1-16

UP100H - handlicher UP100H - UP100H at stand ST1-16
compact light-weight ultrasonic
device

Technical UP100H: Compact ultrasonic lab device (100W, 30kHz) for handheld and
Details stand-mounted operaeon, automaec frequency tuning, amplitude adjustable
from 20 to 100%, pulse adjustable from 0 to 100%, dry running protected,
with 9-pin DSUB interface, light-weight (1.1kg), in portable case, IP40 grade,
etanium horn

Applications Sample Preparaeon, Homogenizaeon, Dispersing & Deagglomeraeon (e.g.

nano parecles), Wet-milling, Emulsifying, Lysis & Cell Disintegraeon,
Extraceon, Degassing, Sonochemistry

Advantages Performance: With 100 wafs power, the UP100H is much more powerful
than an ultrasonic bath or tank.
Flexibility: For handheld or stand-mounted use, with various accessories for
opemal adapeon to your process.
Quality: The ultrasonic lab device UP100H fullfills the highest quality
standards. All devices are designed, engineered and manufactured in
Germany.

Items:
□ Ultrasonic Processor UP100H ○ 115 volts ○ 230 volts
□ Sonotrode MS3 (ep diameter 3mm)
□ Sonotrode MS10 (ep diameter 10mm)
□ Stand ST1-16
□ ST1-Clamp
□ PowerMeterPowMet ○115volts ○230volts

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2021www.hielscher.com

 UP200Ht – A Powerful and Smart Ultrasonic Lab Device
www.hielscher.com/up200ht

Ultrasonic
Device
UP200Ht

UP200Ht – comfortable use as UP200Ht with acrylic sound

handheld homogenizer protection box
Technical UP200Ht: 200 watts, 26kHz; for handheld and stand-mounted use;
Details automatic frequency tuning, amplitude adjustable from 20 to 100%,
pulse adjustable from 0 to 100%, with colored touch-screen & digital
control, operation and control via LAN, automatic data recording, dry
running protected, IP41 grade, titanium horn Ø 10mm, amplitude at
horn 70µm, in portable case
Application Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Emulsifying, Lysis & Cell Disintegration, Extraction, Degassing,
Sonochemistry
Advantages Performance: With 200 watts power, the UP200Ht is much more
powerful than an ultrasonic bath or tank.
Flexibility: For handheld or stand-mounted use, with various
accessories for optimal adaption to your process.
Comfortable Operation: The light-weight device is ergonomically
designed. The operation settings can be adjusted via the colored touch-
screen. All functions are easily and intuitively reachable through one
main menu.
Quality: The UP200Ht device fullfills the highest quality standards. All
devices are designed, engineered and manufactured in Germany.
Items:
□ Ultrasonic Processor UP200Ht ○ 115 volts ○ 230 volts
□ Sonotrode S26d2 (tip diameter 2mm)
□ Sonotrode S26d7 (tip diameter 7mm)
□ Sonotrode S26d14 (tip diameter 14mm)
□ Stand ST1-16
□ Sound Protection Box SPB-L, made from acryl glass

color touch-screen

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UP200St – A Powerful and Robust 200 Watts Ultrasonic Device
for Lab and Small Scale Production
www.hielscher.com/up200st

Ultrasonic
Device
UP200St

UP200St – digital homogenizer UP200St for stamdmounted and

with acrylic sound protection box hand-held use

Technical UP200St: 200 watts, 26kHz; for handheld and stand-mounted use;
Details separated generator and transducer (UP200St-T + UP200St-G) fulfilling
IP51 + IP65 grade, automatic frequency tuning, amplitude adjustable
from 20 to 100%, pulse adjustable from 0 to 100%, with colored touch-
screen & digital control, operation and control via LAN, automatic data
recording, dry running protected, titanium horn Ø 10mm, amplitude at
horn 70µm, in portable case
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Emulsifying, Lysis & Cell Disintegration, Extraction, Degassing,
Sonochemistry & Sono-Catalysis
Advantages Performance: 200 watts power, very reliable & robust device for heavy
duty operation
Flexibility: Handheld or stand-mounted use, with various accessories for
optimal adaption to your process.
Comfortable Operation: The separated design of transducer and
generator allows to place the generator safely outside the operation
area. The operation settings can be adjusted via the colored touch-
screen. All functions are intuitively reachable through one main menu.
Quality: The UP200St device fullfills the highest quality standards. All
devices are designed, engineered and manufactured in Germany.
Items:
□ Ultrasonic Device UP200St (generator + transducer)
□ Sonotrode S26d2 (tip diameter 2mm)
□ Sonotrode S26d7 (tip diameter 7mm)
□ Sonotrode S26d14 (tip diameter 14mm)
□ Stand ST1-16
□ Sound Protection Box SPB-L, made from acryl glass

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 Digital Ultrasonic Device UP200St and VialTweeter
www.hielscher.com/VialTweeter
Ultrasonic
Processor
UP200St
with
VialTweeter

UP200St with VialTweeter UP200St-T, VialTweeter & VialPress

Technical UP200St processor: 200 watts digital ultrasonic processor, with touch display and
Details automatic data recording, ultrasonic frequency 26kHz (auto scan), countdown
(timer): 0.1sec to 99 days, shutdown when final energy input reached (Ws, Wh,
kWh), autom. calibration of the amplitude-dependent idle power, data recording:
amplitude, power, time, temperature on internal SD-Card (1GB), display and
remote control via browser on PC/MAC without software installation, remote
control via PLC
VialTweeter: S26d11x10 block sonotrode, stainless steel, for UP200St,
simultaneous sonication of up to 10 EppendorfVials, for vials and test tubes of
0.5ml, 1.0ml, 1.5ml or 2.0ml volume, e.g. 12x32mm or 15x45mm, other vial sizes
available on request

Applications Sample Preparation, Mixing & Blending, Homogenization, Emulsifying, Dispersing

& Dissolving, Disintegration & Cell Disruption, Deagglomeration & Particle Size
Reduction, Degassing
Advantages • Performance: up to 10 watts into each of the ten vials
• Efficiency:
- higher efficiency than ultrasonic bath or tank as the energy goes only into the
liquid in the vials
-time saving: the power levels allow for sophisticated sonication processes in
short time, similar to direct sonication by a homogenizer
-simultaneous sonication of up to 10 vials under same conditions
• Flexibility:
- the ultrasonic processor UP200St can be used with VialTweeter for indirect
sonication or with sonotrode for direct probe sonication
- various accessories allow use in manifold applications and conditions
- VialTweeter is suitable for vials of the most common sizes, brands and designs.
Possibility for indirect sonication of a single vessels with up to 500ml with the
mountable VialPress

Items:
□ Ultrasonic Processor UP200St ○ 115volts ○ 230volts
□ VialTweeter S26d11x10 block sonotrode
□ VialPress

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 Digital Ultrasonic Device UP400St (400 watts, 24hHz)
www.hielscher.com/up400st

Stand-
mounted
Ultrasonic
Device
UP400St

The UP400St features

UP400St with SD-card slot, LAN port +
400 W powerful ultrasonicator temperature sensor
Technical UP400St-spec: 400 watts, 24kHz; for stand-mounted use; automatic
Details frequency tuning, amplitude adjustable from 20 to 100%, pulse
adjustable from 0 to 100%, with colored touch-screen & digital control,
operation and control via LAN, automatic data recording, dry running
protected, IP41 grade, titanium horn, in portable case
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Wet-milling & Grinding (e.g. nano materials), Emulsifying, Lysis & Cell
Disintegration, Extraction, Sonochemistry
Advantages Effectiveness: High-power lab device for sonication of larger volumes
from 5 mL up to 4L in the batch and approx. 10 to 50 litres per hour
with flow cell.
Flexibility: Beaker sonication and continuous sonication for
applications in lab & bench-top scale and for small production.
Simplicity: The operation settings can be adjusted via the colored
touch-screen. All functions are easily and intuitively reachable through
one main menu. The UP400St-spec is simple to use and easy to clean.

Items:
□ Ultrasonic Processor UP400St ○ 115 volt ○ 230 volt
□ Sonotrode H7 with 7mm tip diameter
□ Sonotrode H22 with 22mm tip diameter
□ Flow Cell D22K stainless steel, volume approx. 15ml
□ Sonotrode H22D with seal for flow cell D22K
□ Stand ST1-16
□ Sound Protection Box SB1-16

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2021 www.hielscher.com
 UIP400MTP – 96-Well-Plate Sonicator
www.hielscher.com/uip400mtp

Ultrasonic
Processor
UIP400MTP

The UIP400MTP facilitates the

UIP400MTP for multi-well plate simultaneous preparation of multiple
sonication samples
Technical Details The UIP400MTP is a 400 wafs, 20kHz ultrasonic processor for the reliable and
reproducible ultrasonic sample preparaeon of any standard mule-well plate /
microeter plate. Smart sopware and an intuieve menu ensure user-friendliness
and simple operaeon. A built-in heat exchanger with recirculaeon pump allows
the microeter plate to be cooled or tempered during sonicaeon. A laboratory
cooler is required for this purpose (not included). The UIP400MTP has a coolant
inlet and outlet. The PT100 temperature sensor can be placed in one of the
sample wells for temperature monitoring and control.
Applications Sample preparation including lysis & cell disintegration, DNA shearing,
solubilization, homogenization of biological samples

Advantages Effectiveness: Powerful, state-of-the-art ultrasonic device with 400 watts power
Reproducibility: Exact reproducibility by full control over the parameters such
as energy input (Ws/mL), amplitude, temperature
User-friendliness: Designed for easy use and reliable results. The smart features
allow to program and pre-set various sonication modes (e.g., energy input,
amplitude, cycle mode, temperature, time)

Ultrasonic Processor UIP400MTP

with digital touch display + sophisticated PT100 temperature sensor
software with recirculation pump
programmable settings with connection ports for lab cooler
built-in SD card for automatic data protocolling browser remote control

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420

 www.hielscher.com/SonoStep

SonoStep – Multi-Functional Ultrasonic Device with integrated

Stirring and Pumping Functions
Ultrasonic
Device
UP200St-TD
with SonoStep

generator UP200St + transducer TD + top TD + SonoStep for combined

piece SonoStep pumping, stirring & sonication

Technical The SonoStep is the perfect device for reliable and comfortable sample preparation.
Details The three essential functions of continuous sonication, stirring and pumping are
integrated in a compact device. Ultrasound, and centrifugal pump are integrated into
an agitated stainless steel beaker.
The 200 watts digital ultrasonic generator is equipped with touch display and
automatic data recording, ultrasonic frequency 26kHz (auto scan); countdown timer,
shutdown when final energy input reached (Ws, Wh, kWh); auto-calibration of the
amplitude-dependent idle power; data recording: amplitude, power, time,
temperature on internal SD-Card; display+remote control via browser on PC/MAC
without software installation, remote control via PLC.
Applications Small Volume Processing & Sample Preparation before Analysis: Sonication, Stirring
and Pumping in one device

Advantages • Performance:
- Consistent sonication with up to 200 watts for sample preparation.
- The SonoStep pumps, stirres and sonicates the sample in recirculation.
- Mixing/ Dispersing/ Deagglomeration + De-aeration by Power Ultrasound
- Direct connection to the analytical device for most accurate measurements.
- No sample loss, no cross-contamination
• Efficiency:
- effortless sample preparation by simple setup and operation of one device
- time saving: the power levels allow for sophisticated sonication in a short time,
similar to direct sonication by a homogenizer with the advantage that the
SonoStep delivers the sonicated sample directly to the analytical device
- direct connection of the SonoStep with the analytical device, e.g. for particle
measurement
• Flexibility:
- Simple setup and operation
- Quick-locking mechanism for fast and simple cleaning
- Simply exchanable hose or pipe connections
- Cuphorn and flow cell for specific applications are additionally available

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UIP500hdT – Industrial Ultrasonic Device for Benchtop and Small Scale
Production
www.hielscher.com/500

Ultrasonic
Processor
UIP500hdT

UIP500hdT for batch sonication UIP500hdT for inline sonication

Technical Ultrasonic processor UIP500hdT (500W, 20kHz) consisting of

Details transducer and generator; coloured touch display and intuitive digital
control menu; SD-Card slot for automatic recording of all sonication
parameters, browser remote control, temperature sensor, Ethernet:
Browser Remote Control via LAN web interface; automatic frequency
tuning, amplitude 25 micron, amplitude adjustable from 50 to 100%,
dry running protected, transducer IP65 grade, titanium horn
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Wet-milling & Grinding (e.g. nano materials), Emulsifying, Lysis & Cell
Disintegration, Extraction, Sonochemistry, Gourmet Applications

Advantages Effectiveness: High-power, high performance ultrasonic device with

500 watts power, various recirculation setups for continuous
processing,
Reproducibility: Exact reproducibility by full control over the
parameters „ Amplitude, Pressure, Temperature, Viscosity, and
Concentration“
Scalability: All results achieved can be scaled up linearly.
Industrial Grade: Full industrial grade, for heavy-duty operation and
permanent use 24 hours per day (24h/7d)

Front panel of the generator UIP500hdT with multi-colour touch display

All process data are automatically stored on an internal SD-Card

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 Ultrasonic Processor UIP1000hdT
www.hielscher.com/1000
UIP1000hdT
transducer and
generator

UIP1000hdT set for batch and UIP1000hdT recirculation setup

inline sonication with flow cell for continuous
sonication

Technical Details Ultrasonic processor UIP1000hdT (1000W, 20kHz) consisting of

transducer and generator; coloured touch display and intuitive
digital control menu; SD-Card slot for automatic recording of all
sonication parameters, browser remote control, temperature
sensor, Ethernet: Browser Remote Control via LAN web interface;
automatic frequency tuning, amplitude 25 micron, amplitude
adjustable from 50 to 100%, dry running protected, transducer IP65
grade, titanium horn
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano
particles), Wet-milling & Grinding (e.g. nano materials),
Emulsifying, Lysis & Cell Disintegration, Extraction, Sonochemistry
Advantages Effectiveness: High-power, high performance ultrasonic device with
1000 watts power, various recirculation setups for continuous
processing,
Reproducibility: Exact reproducibility by full control over the
parameters „ Amplitude, Pressure, Temperature, Viscosity, and
Concentration“
Scalability: All results achieved can be scaled up linearly.
Industrial Grade: Full industrial grade, for heavy-duty operation and
permanent use 24 hours per day (24h/7d)

Front panel of the generator UIP1000hdT with multi-color touch display

All process data are automatically storaged on an internal SD-Card

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UIP1500hdT – Industrial Ultrasonic Device for Benchtop and Production
www.hielscher.com/1500

Ultrasonic
Processor
UIP1500hdT

UIP1500hdT transducer and

generator
UIP1500hdT for inline sonication

Technical Ultrasonic processor UIP1500hdT (1500W, 20kHz) consisting of

Details transducer and generator; coloured touch display and intuitive digital
control menu; SD-Card slot for automatic recording of all sonication
parameters, browser remote control, temperature sensor, Ethernet:
Browser Remote Control via LAN web interface; automatic frequency
tuning, amplitude 25 micron, amplitude adjustable from 50 to 100%,
dry running protected, transducer IP65 grade, titanium horn
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles),
Wet-milling & Grinding (e.g. nano materials), Emulsifying, Lysis & Cell
Disintegration, Extraction, Sonochemistry & Sonocatalysis

Advantages Effectiveness: High-power, high performance ultrasonic device with

1500 watts power, various recirculation setups for continuous
processing,
Reproducibility: Exact reproducibility by full control over the
parameters „ Amplitude, Pressure, Temperature, Viscosity, and
Concentration“
Scalability: All results achieved can be scaled up linearly.
Industrial Grade: Full industrial grade, for heavy-duty operation and
permanent use 24 hours per day (24h/7d)

Front panel of the generator UIP1500hdT with multi-colour touch display

All process data are automatically stored on an internal SD-Card

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 UIP2000hdT – Powerful Industrial Ultrasonic Device
www.hielscher.com/uip2000

Ultrasonic
Processor
UIP2000hdT

UIP2000hdT transducer and

generator UIP2000hdT installation

Technical Ultrasonic processor UIP2000hdT (2000W, 20kHz) consisting of transducer

Details and generator; digital control, color touch display, intelligent data recording
on internal SD card, automatic frequency tuning, amplitude 25 micron,
amplitude adjustable from 20 to 100%, dry running protected, remote control
via browser on PC or MAC without software installation, transducer IP65
grade, titanium horn

Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles), Wet-

milling & Grinding (e.g. nano materials), Emulsifying, Lysis & Cell
Disintegration, Extraction, Sonochemistry & Sonocatalysis

Advantages Effectiveness: High-power, high performance ultrasonic device with 2000

watts power, various recirculation setups for continuous processing,
Reproducibility: Exact reproducibility by full control over the parameters
„ Amplitude, Pressure, Temperature, Viscosity, and Concentration“
Scalability: All results achieved can be scaled up linearly.
Industrial Grade: Full industrial grade, for heavy-duty operation and
permanent use 24 hours per day (24h/7d), scale-up by cluster installation

Items:
□ Ultrasonic processor UIP2000hdT
○ 115 volts ○ 230 volts
□ Sonotrode BS4d34 (tip diameter 34mm) □ Flow Cell Insert34
□ Sonotrode BS4d40 (tip diameter 40mm) □ Booster Horn B4-2
□ O-Ring-Flange RFLA100 □ Stand ST2
□ Flow Cell FC100L1-1S w/ cooling jacket □ Sound Enclosure

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2021www.hielscher.com

 UIP4000hdT – Powerful Industrial Ultrasonic Device
www.hielscher.com/uip4000hdT

Ultrasonic
Processor
UIP4000hdT

UIP4000hdT transducer cabinet and

UIP4000hdT (4kW, 20kHz) generator

Technical Ultrasonic processor UIP4000hdT (4000W, 20kHz) consisting of transducer

Details and generator; digital control, color touch display, intelligent data recording
on internal SD card, automatic frequency tuning, amplitude 25 micron,
amplitude adjustable from 20 to 100%, dry running protected, remote
control via browser on PC or MAC without software installation, transducer
IP52 grade, titanium horn
Applications Homogenization, Dispersing & Deagglomeration (e.g. nano particles), Wet-
milling & Grinding (e.g. nano materials), Nano-Emulsions, Lysis & Cell
Disintegration, Extraction, Sonochemistry & Sonocatalysis

Advantages Effectiveness: High-power, high performance ultrasonic device with 4000

watts power, various recirculation setups for continuous processing
Reproducibility: Exact reproducibility by full control over the parameters
„ Amplitude, Pressure, Temperature, Viscosity, and Concentration“
Scalability: All results achieved can be scaled up linearly.
Industrial Grade: Full industrial grade, for heavy-duty operation and
permanent use 24 hours per day (24h/7d), scale-up by cluster installation

Items & accessories available:

□ Ultrasonic processor UIP4000hdT □ various booster horns

consisting of transducer and generator □ Sound protection cabinet
□ various block sonotrodes
□ various Cascatrodes
□ various flow cells and reactors w/ cooling
jacket
□ pressure sensor

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2024www.hielscher.com

 SonoSta_on - Hielscher’s pump solu_on
www.hielscher.com/sonostation

Features:
• easy-to-use
• easy-to-clean
• fully integrated
• simple setup
• small footprint
• holds up to 4kW sonica_on power (2x UIP500 to UIP2000hdT)
• robust for everyday use (pilot or produc_on)
• flexible for process development
• stainless steel tank
• no sedimenta_on as in horizontal pumps

Technical Details:
• stainless steel
• 230VAC or 115VAC single phase for standard wall outlet
• Progressive cavity pump for constant flow and constant pressure
• with VFD, 40 to 495RPM
• 15-180L/h
• max 5barg
• self priming
• high viscosity, even grout

Ultrasonic processing is just one step in your

process development or everyday
produc_on. The installa_on and opera_on of
the ultrasonic reactor should as simple as
possible. The SonoSta_on is an easy-to-use
pumping system to move your liquid material
to the ultrasonic reactor at constant flow and
constant pressure. We integrated a 38L
s_rred tank (jacketed) with a progressive
cavity pump into a mobile processing system.
We even included a stand for up to two
ultrasonic reactors. This high level of
integra_on reduces the number and size or
wehed parts, fijngs and connectors. This
makes the SonoSta_on easier to use and
easier to clean than a conven_onal setup. It
reduces the foot-print too.

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2024www.hielscher.com

 Good Reasons for Hielscher Sonicators
High power ultrasonic equipment: Hielscher's ultrasonic machines work in the low frequency/
high power range and are highly reliable and robust. All units are built to run 24/7 (even the
lab devices). All devices are capable to run at full load and deliver the label power. (Verify the
delivered energy from Hielscher's ultrasonic device into the liquid by using the wattmeter - and
compare it with the results achieved by competitor's ultrasonic devices => label power does
mostly not mean delivered energy into the liquid!)
High efficiency: A very high efficiency in the conversion of electrical energy into mechanical
oscillations of the sonotrode makes a closed transducer housing possible. There are no louvers
in the transducer case. As the energy loss, which would cause a heat-up in the closed
transducer housing is very low, no forced cooling, such as compressed air or water is needed.
More important this means, that more energy is transmitted into the liquid, resulting in a better
sonication. The overall energy efficiency of Hielscher's industrial units is approx. 80-90% from
the power plug into the liquid.
Sophisticated, Smart Technology: Hielscher ultrasonicators feature automatic data protocoling
on a built-in SD card, smart software, user-friendly operation via coloured touch-display, an
intuitive menu and settings, programmable settings, browser remote control, LAN connection,
Ethernet connection
Industrial grade: The transducers of the industrial ultrasonic machines are IP65 grade and can
be installed in very demanding environments. The cleaning is easy as the transducer and flow
cells can be showered completely. Hielscher's equipment gives full control over the most
important sonication parameters: amplitude, pressure, temperature, viscosity
Cleaning: Simple cleaning and sanitizing of the ultrasonic setup as the reactor chamber have
no hidden orifices. The transducer and flow cells can be showered completely as they are IP65
grade. Just flush the system with water or cleaning agents and use the ultrasound as cleaner in
place (CIP cleaner-in-place/ SIP sanitizer-in-place)
Service, consulting and support: Hielscher does not only supply the ultrasonic machinery, but
helps also to optimize the process and to find the best installation setup. Maintenance,
installation service and training can be provided upon request.
Manufactured in Germany: All devices are made in Germany. Hielscher guarantees with its
name for high quality machinery. All devices are tested in continuous running before they are
shipped to the customer. All standard items are in stock and can be shipped immediately.
Scale-up to any size needed: By building the worldwide most powerful ultrasonic machine with
16kW per ultrasonic unit, Hielscher is capable to supply the suitable ultrasonic setup for any
process volume. The sonotrodes and accessories for scale-up can be customized ideally
matching your process requirements.
Exact reproducibility and linear scalability: All the obtained results can reproduced exactly and
can be scaled completely linearly. After testing various setups, the configuration found to be
best can be used to run continuously (24h/7d) under production conditions.
Fixed frequency: Hielscher's ultrasonic machinery is equipped with an intelligent automatic
frequency tuning. That means the generator finds the optimal operational frequency of the
attached transducer-booster-sonotrode configuration, automatically. The generator maintains
the set amplitude. This results in a higher overall energy efficiency and reliability.
Continuous inline processing: Continuous sonication results in an uniform and consistent
product. Continuous processing requires less cleaning and provides a cleaner production
environment as less material handling accrues. The closed sonication system secures that no
unwanted material enter during the processing step.

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com

 Hielscher Ultrasonics
Bench-top & Industrial Ultrasonic Systems

• UIP500hdT (500W)
• UIP1000hdT (1kW)
• UIP15000hdT (1.5 kW)
• UIP2000hdT (2 kW)
• UIP4000hdT (4 kW)
• UIP6000hdT (6 kW)
• UIP16000 (16 kW)

Hielscher Ultrasonics GmbH www.hielscher.com; [email protected] Tel.: +49 (0)3328/437-420 © 2023www.hielscher.com