Sem 121

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SYLLABUS

Semester I
PT105. HUMAN ANATOMY AND PHYSIOLOGY-I (Theory)
45 Hours
Scope: This subject is designed to impart fundamental knowledge on the structure and
functions of the various systems of the human body. It also helps in understanding both
homeostatic mechanisms. The subject provides the basic knowledge required to
understand the various disciplines of pharmacy.
Objectives: Upon completion of this course the student should be able to
1. Explain the gross morphology, structure and functions of various organs of the human
body.
2. Describe the various homeostatic mechanisms and their imbalances.
3. Identify the various tissues and organs of different systems of human body.
4. Perform the various experiments related to special senses and nervous system.
5. Appreciate coordinated working pattern of different organs of each system

Course Content:
Unit-I 10hours
 Introduction to human body
Definition and scope of anatomy and physiology, levels of structural
organization and body systems, basic life processes, homeostasis, basic
anatomical terminology.
 Cellular level of organization
Structure and functions of cell, transport across cell membrane, cell
division, cell junctions. General principles of cell communication,
intracellular signaling pathway activation by extracellular signal molecule,
Forms of intracellular signaling: a) Contact-dependent b) Paracrine c)
Synaptic d) Endocrine
 Tissue level of organization
Classification of tissues, structure, location and functions of epithelial,
muscular and nervous and connective tissues.

Unit II 10 hours
 Integumentary system
Structure and functions of skin

 Skeletal system
Divisions of skeletal system, types of bone, salient features and functions of
bones of axial and appendicular skeletal system
Organization of skeletal muscle, physiology of muscle contraction,
neuromuscular junction
 Joints
Structural and functional classification, types of joints movements and its
articulation

Unit III 10hours


 Body fluids and blood
 Body fluids, composition and functions of blood, hemopoeisis, formation of
hemoglobin, anemia, mechanisms of coagulation, blood grouping, Rh factors,
transfusion, its significance and disorders of blood, Reticuloendothelial system.
 Lymphatic system
Lymphatic organs and tissues, lymphatic vessels, lymph circulation and functions of
lymphatic system

Unit IV 08hours
Peripheral nervous system:
Classification of peripheral nervous system: Structure and functions of
sympathetic and parasympathetic nervous system.
Origin and functions of spinal and cranial nerves.
 Special senses
Structure and functions of eye, ear, nose and tongue and their disorders.

Unit-V 07hours
 Cardiovascular system
Heart – anatomy of heart, blood circulation, blood vessels, structure and functions of
artery, vein and capillaries, elements of conduction system of heart and heart beat, its
regulation by autonomic nervous system, cardiac output, cardiac cycle. Regulation of
blood pressure, pulse, electrocardiogram and disorders of heart.
PT195. HUMAN ANATOMY AND PHYSIOLOGY (Practical)
4 Hours/week
Practical physiology is complimentary to the theoretical discussions in
physiology. Practicals allow the verification of physiological processes discussed
in theory classes through experiments on living tissue, intact animals or normal
human beings. This is helpful for developing an insight on the subject.

1. Study of compound microscope.


2. Microscopic study of epithelial and connective tissue
3. Microscopic study of muscular and nervous tissue
4. Identification of axial bones
5. Identification of appendicular bones
6. Introduction to hemocytometry.
7. Enumeration of white blood cell (WBC)count
8. Enumeration of total red blood corpuscles (RBC)count
9. Determination of bleeding time
10. Determination of clotting time
11. Estimation of hemoglobin content
12. Determination of blood group.
13. Determination of erythrocyte sedimentation rate (ESR).
14. Determination of heart rate and pulse rate.
15. Recording of blood pressure.

Recommended Books (Latest Editions)


1. Essentials of Medical Physiology by K. Sembulingam and P. Sembulingam. Jaypee
brothers medical publishers, New Delhi.
2. Anatomy and Physiology in Health and Illness by Kathleen J.W. Wilson, Churchill
Livingstone, NewYork
3. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co,
Riverview, MIUSA
4. Text book of Medical Physiology- Arthur C, Guyton and John. E. Hall. Miamisburg, OH,
U.S.A.
5. Principles of Anatomy and Physiology by Tortora Grabowski. Palmetto, GA, U.S.A.
6. Textbook of Human Histology by Inderbir Singh, Jaypee brother’s medical publishers,
NewDelhi.
7. Textbook of Practical Physiology by C.L. Ghai, Jaypee brother’s medical publishers,
NewDelhi.
8. Practical workbook of Human Physiology by K. Srinageswari and Rajeev Sharma,
Jaypee brother’s medical publishers, NewDelhi.
Reference Books (Latest Editions)
1. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co,
Riverview, MIUSA
2. Text book of Medical Physiology- Arthur C, Guyton and John. E. Hall. Miamisburg, OH,
U.S.A.
3. Human Physiology (vol 1 and 2) byDr. C.C. Chatterrje ,Academic Publishers Kolkata
PT101. PHARMACEUTICAL ANALYSIS (Theory)
45 Hours
Scope: This course deals with the fundamentals of analytical chemistry and principles of
electrochemical analysis of drugs

Objectives: Upon completion of the course student shall be able to


 understand the principles of volumetric and electro chemical analysis
 carryout various volumetric and electrochemical titrations
 develop analytical skills

Course Content:
UNIT-I 10Hours
(a) Pharmaceutical analysis- Definition and scope
i) Different techniques of analysis
ii) Methods of expressing concentration
iii) Primary and secondary standards.
iv) Preparation and standardization of various molar and normal solutions-
Oxalic acid, sodium hydroxide, hydrochloric acid, sodium thiosulphate,
sulphuric acid, potassium permanganate and cericammonium sulphate
(b) Errors: Sources of errors, types of errors, methods of minimizing errors,
accuracy, precision and significant figures
(c) Pharmacopoeia, Sources of impurities in medicinal agents, limit tests.
UNIT-II 10Hours
 Acid base titration: Theories of acid base indicators, classification of
acid base titrations and theory involved in titrations of strong, weak,
and very weak acids and bases, neutralization curves
 Non aqueous titration: Solvents, acidimetry and alkalimetry titration and
estimation of Sodium benzoate and Ephedrine HCl
UNIT-III 10Hours
 Precipitation titrations: Mohr’s method, Volhard’s, Modified
Volhard’s, Fajans method, estimation of sodium chloride.
 Complexometric titration: Classification, metal ion indicators, masking
and demasking reagents, estimation of Magnesium sulphate, and calcium
gluconate.
 Gravimetry: Principle and steps involved in gravimetric analysis. Purity
of the precipitate: co-precipitation and post precipitation, Estimation of
barium sulphate.

 Basic Principles, methods and application of diazotization titration.

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UNIT-IV 08Hours
Redox titrations
(a) Concepts of oxidation and reduction
(b) Types of redox titrations (Principles and applications)
Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry, Titration with
potassium iodate
UNIT-V 07Hours
 Electrochemical methods of analysis
 Conductometry- Introduction, Conductivity cell, Conductometric
titrations, applications.
 Potentiometry - Electrochemical cell, construction and working
of reference (Standard hydrogen, silver chloride electrode and
calomel electrode) and indicator electrodes (metal electrodes and
glass electrode), methods to determine end point of potentiometric
titration and applications.
 Polarography - Principle, Ilkovic equation, construction and
working of dropping mercury electrode and rotating platinum
electrode, applications

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PT191. PHARMACEUTICAL ANALYSIS (Practical)
4 Hours / Week
I Limit Test of the following
(1) Chloride
(2) Sulphate
(3) Iron
(4) Arsenic

II Preparation and standardization of


(1) Sodium hydroxide
(2) Sulphuric acid
(3) Sodium thiosulfate
(4) Potassium permanganate
(5) Ceric ammoniumsulphate
III Assay of the following compounds along with Standardization ofTitrant
(1) Ammonium chloride by acid base titration
(2) Ferrous sulphate by Cerimetry
(3) Copper sulphate by Iodometry
(4) Calcium gluconate by complexometry
(5) Hydrogen peroxide by Permanganometry
(6) Sodium benzoate by non-aqueous titration
(7) Sodium Chloride by precipitation titration
IV Determination of Normality by electro-analytical methods
(1) Conductometric titration of strong acid against strong
(2) base
(3) Conductometric titration of strong acid and weak acid against strongbase
(4) Potentiometric titration of strong acid against strongbase

Recommended Books: (Latest Editions)

1. A.H. Beckett & J.B. Stenlake's, Practical Pharmaceutical Chemistry Vol I &II, Stahlone
Press of University of London
2. A.I. Vogel, Text Book of Quantitative Inorganic analysis
3. P. Gundu Rao, Inorganic Pharmaceutical Chemistry
4. Bentley and Driver's Textbook of Pharmaceutical Chemistry
5. John H. Kennedy, Analytical chemistry principles
6. Indian Pharmacopoeia.

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PT106. PHARMACEUTICS- I (Theory)
45 Hours
Scope: This course is designed to impart a fundamental knowledge on the preparatory
pharmacy with arts and science of preparing the different conventional dosage forms.
Objectives: Upon completion of this course the student should be able to:
 Know the history of profession of pharmacy
 Understand the basics of different dosage forms, pharmaceutical incompatibilities and
pharmaceutical calculations
 Understand the professional way of handling the prescription
 Preparation of various conventional dosage forms

Course Content:
UNIT–I 10Hours
 Historical background and development of profession of pharmacy: History
of profession of Pharmacy in India in relation to pharmacy education, industry and
organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP
and Extra Pharmacopoeia.
 Dosage forms: Introduction to dosage forms, classification and definitions
 Prescription: Definition, Parts of prescription, handling of Prescription and
Errors in prescription.
 Posology: Definition, Factors affecting posology. Pediatric dose
calculations based on age, body weight and body surface area.
UNIT–II 10Hours
 Pharmaceutical calculations: Weights and measures – Imperial & Metric
system, Calculations involving percentage solutions, alligation, proof spirit and
isotonic solutions based on freezing point depression and molecular weight
method.

 Powders: Definition, classification, advantages and disadvantages, Simple &


compound powders – official preparations, dusting powders, effervescent,
efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.

 Liquid dosage forms: Advantages and disadvantages of liquid dosage forms.


Excipients used in formulation of liquid dosage forms. Solubility enhancement
techniques

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UNIT–III 08Hours
 Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes,
Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and
Lotions.
 Biphasicliquids:
 Suspensions: Definition, advantages and disadvantages, classifications,
Preparation of suspensions; Flocculated and Deflocculated suspension & stability
problems and methods to overcome, evaluation.
 Emulsions: Definition, classification, emulsifying agent, test for the identification
of type of Emulsion, Methods of preparation & stability problems and methods to
overcome, evaluation.

UNIT–IV 08Hours
 Suppositories: Definition, types, advantages and disadvantages, types of bases,
methods of preparations. Displacement value & its calculations, evaluation of
suppositories.
 Pharmaceutical incompatibilities: Definition, classification, physical, chemical
and therapeutic incompatibilities with examples.

UNIV–V 07Hours
 Semisolid dosage forms: Definitions, classification, mechanisms and factors
influencing dermal penetration of drugs. Preparation of ointments, pastes, creams
and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid
dosage forms

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PT196 PHARMACEUTICS I (Practical)

3 Hours / week
1 .Syrups
a) Simple SyrupIP’66
b) Compound syrup of Ferrous PhosphateBPC’68
2. Elixirs a) Piperazine citrateelixir
b) Paracetamol pediatric elixir
3. Linctus a) Terpin Hydrate LinctusIP’66

b) Iodine Throat Paint (Mandles Paint)


4. Solutions
a) Strong solution of ammonium acetate
b) Cresol with soap solution
c) Lugol’s solution
5. Suspensions
a) Calamine lotion
b) Magnesium Hydroxide mixture
c) Aluminimum Hydroxide gel
6. Emulsions a) Turpentine Liniment
b) Liquid paraffin emulsion
7. Powders andGranules
a) ORS powder(WHO)
b) Effervescent granules
c) Dusting powder
d) Divided powders
8. Suppositories
a) Glycero gelatin suppository
b) Coca butter suppository
c) Zinc Oxide suppository
8. Semisolids
a) Sulphur ointment
b) Non staining-iodine ointment with methylsalicylate
c) Carbopalgel
9. Gargles and Mouthwashes
a) Iodine gargle
b) Chlorhexidine mouthwash

Recommended Books: (Latest Editions)

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1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott
Williams and Walkins, New Delhi.
2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers,
NewDelhi.
3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone,
Edinburgh.
4. Indian pharmacopoeia.
5. British pharmacopoeia.
6. Lachmann. Theory and Practice of Industrial Pharmacy, Lea& Febiger Publisher, The
University of Michigan.
7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott
Williams, New Delhi.
8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society,
Elsevier Health Sciences, USA.
10. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC,
NewYork.
11. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker,
INC, New York.
12. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions
andSuspensions, Marcel Dekker, INC, New York.

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PT 103 PHARMACEUTICAL INORGANIC CHEMISTRY (Theory)
45 Hours
Scope: This subject deals with the monographs of inorganic drugs and pharmaceuticals.

Objectives: Upon completion of course student shall be able to


 know the sources of impurities and methods to determine the impurities ininorganic
drugs and pharmaceuticals
 understand the medicinal and pharmaceutical importance of inorganic compounds

Course Content:

UNIT I 10Hours

 Impurities in pharmaceutical substances: History of Pharmacopoeia,


Sources and types of impurities, principle involved in the limit test for
Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test
for Chloride and Sulphate

General methods of preparation, assay for the compounds superscripted


with asterisk (*), properties and medicinal uses of inorganic compounds
belonging to the following classes

UNITII 10Hours

 Acids, Bases and Buffers: Buffer equations and buffer capacity in general,
buffers in pharmaceutical systems, preparation, stability, buffered isotonic
solutions, measurements of tonicity, calculations and methods of adjusting
isotonicity.
 Major extra and intracellular electrolytes: Functions of major
physiological ions, Electrolytes used in the replacement therapy: Sodium
chloride*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt
(ORS), Physiological acid base balance.
 Dental products: Dentifrices, role of fluoride in the treatment of dental
caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc
eugenol cement.

UNITIII 10Hours

 Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl
Antacid: Ideal properties of antacids, combinations of antacids, Sodium

[Type text]
Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture
Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and
Bentonite
Antimicrobials: Mechanism, classification, Potassium permanganate, Boric
acid, Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations

UNITIV 08Hours

 Miscellaneous compounds
Expectorants: Potassium iodide, Ammonium chloride*.
Emetics: Copper sulphate*, Sodium potassium tartarate
Haematinics: Ferrous sulphate*, Ferrous gluconate
Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium
nitrite333
Astringents: Zinc Sulphate, Potash Alum

UNITV 07Hours

 Radiopharmaceuticals: Radio activity, Measurement of radioactivity,


Properties of α, β, γ radiations, Half life, radio isotopes and study of radio
isotopes - Sodium iodide I131, Storage conditions, precautions &
pharmaceutical application of radioactive substances.

[Type text]
PT193 PHARMACEUTICAL INORGANIC CHEMISTRY (Practical)
4 Hours / Week
I Limit tests for following ions
Limit test for Chlorides and Sulphates
Modified limit test for Chlorides and Sulphates
Limit test for Iron
Limit test for Heavy metals
Limit test for Lead
Limit test for arsenic
II Identification test
Magnesium hydroxide
Ferrous sulphate
Sodium bicarbonate
Calcium gluconate
Copper sulphate
III Test forpurity
Swelling power of Bentonite
Neutralizing capacity of aluminum hydroxide gel
Determination of potassium iodate and iodine in potassium Iodide
IV Preparation of inorganicpharmaceuticals
Boric acid
Potash alum
Ferrous sulphate

Recommended Books (Latest Editions)


1. A.H. Beckett & J.B. Stenlake's, Practical Pharmaceutical Chemistry Vol I &II,
Stahlone Press of University of London, 4thedition.
2. A.I. Vogel, Text Book of Quantitative Inorganic analysis
3. P. Gundu Rao, Inorganic Pharmaceutical Chemistry, 3rd Edition
4. M.L Schroff, Inorganic Pharmaceutical Chemistry
5. Bentley and Driver's Textbook of Pharmaceutical Chemistry
6. Anand & Chatwal, Inorganic Pharmaceutical Chemistry
7. Indian Pharmacopoeia

[Type text]
PTB 184 REMEDIAL BIOLOGY (Theory)
30 Hours

Scope: To learn and understand the components of living world, structure and functional
system of plant and animal kingdom.

Objectives: Upon completion of the course, the student shall be able to


 know the classification and salient features of five kingdoms of life
 understand the basic components of anatomy & physiology of plant
 know understand the basic components of anatomy & physiology animal with
special reference to human

UNITI 07Hours

Living world:
 Definition and characters of living organisms
 Diversity in the living world
 Binomial nomenclature
 Five kingdoms of life and basis of classification. Salient features of Monera,
Potista, Fungi, Animalia and Plantae,Virus,

Morphology of Flowering plants


 Morphology of different parts of flowering plants – Root, stem, inflorescence,
flower, leaf, fruit, seed.
 General Anatomy of Root, stem, leaf of monocotyledons & Dicotylidones.

UNITII 07Hours

Body fluids and circulation


 Composition of blood, blood groups, coagulation of blood
 Composition and functions of lymph
 Human circulatory system
 Structure of human heart and blood vessels
 Cardiac cycle, cardiac output and ECG
Digestion and Absorption
 Human alimentary canal and digestive glands
 Role of digestive enzymes
 Digestion, absorption and assimilation of digested food
Breathing and respiration
 Human respiratory system
 Mechanism of breathing and its regulation
 Exchange of gases, transport of gases and regulation of respiration
 Respiratory volumes

[Type text]
UNITIII 07Hours

Excretory products and their elimination


 Modes of excretion
 Human excretory system- structure and function
 Urine formation
 Rennin angiotensin system
Neural control and coordination
 Definition and classification of nervous system
 Structure of a neuron
 Generation and conduction of nerve impulse
 Structure of brain and spinal cord
 Functions of cerebrum, cerebellum, hypothalamus and medulla oblongata
Chemical coordination and regulation
 Endocrine glands and their secretions
 Functions of hormones secreted by endocrine glands
Human reproduction
 Parts of female reproductive system
 Parts of male reproductive system
 Spermatogenesis and Oogenesis
 Menstrual cycle

UNITIV 05Hours
Plants and mineral nutrition:
 Essential mineral, macro and micronutrients
 Nitrogen metabolism, Nitrogen cycle, biological nitrogen fixation

Photosynthesis
 Autotrophic nutrition, photosynthesis, Photosynthetic pigments, Factors affecting
photosynthesis.

UNITV 04Hours

Plant respiration: Respiration, glycolysis, fermentation (anaerobic).


Plant growth and development
 Phases and rate of plant growth, Condition of growth, Introduction to plant
growth regulators
Cell - The unit of life
 Structure and functions of cell and cell organelles. Cell division
Tissues
 Definition, types of tissues, location and functions.

[Type text]
Text Books
a. Text book of Biology by S. B.Gokhale
b. Biology for Engineers by Uma Devi, Khanna Book Publishing House.
c. A Text book of Biology by Dr. Thulajappa and Dr. Seetaram.

Reference Books
a. A Text book of Biology by B.V. Sreenivasa Naidu
b. A Text book of Biology by Naidu and Murthy
c. Botany for Degree students By A.C. Dutta.
d. Outlines of Zoology by M. Ekambaranatha ayyer and T. N. Ananthakrishnan.
e. A manual for pharmaceutical biology practical by S.B. Gokhale and C. K. Kokate

[Type text]
PTB 185 REMEDIAL BIOLOGY (Practical)
30 Hours
1. Introduction to experiments in biology
a) Study of Microscope
b) Section cutting techniques
c) Mounting and staining
d) Permanent slide preparation
2. Study of cell and its inclusions
3. Study of Stem, Root, Leaf, seed, fruit, flower and their modifications
4. Detailed study of frog by using computer models
5. Microscopic study and identification of tissues pertinent to Stem,
Root Leaf, seed, fruit and flower
6. Identification of bones
7. Determination of blood group
8. Determination of blood pressure
9. Determination of tidal volume

Reference Books
1. Practical human anatomy and physiology. by S.R.Kale and R.R.Kale.
2. A Manual of pharmaceutical biology practical by S.B.Gokhale, C.K.Kokate
and S.P.Shriwastava.
3. Biology practical manual according to National core curriculum .Biology forum
of Karnataka. Prof.M.J.H.Shafi

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M 183 REMEDIAL MATHEMATICS (Theory)

30 Hours

Scope: This is an introductory course in mathematics. This subject deals with the
introduction to Partial fraction, Logarithm, matrices and Determinant, Analytical
geometry, Calculus, differential equation and Laplace transform.

Objectives: Upon completion of the course the student shall be able to:-
1. Know the theory and their application in Pharmacy
2. Solve the different types of problems by applying theory
3. Appreciate the important application of mathematics in Pharmacy

Course Content:

UNIT–I 06Hours
 Partial fraction
Introduction, Polynomial, Rational fractions, Proper and Improper fractions,
Partial fraction , Resolving into Partial fraction, Application of Partial
Fraction in Chemical Kinetics and Pharmacokinetics

 Logarithms
Introduction, Definition, Theorems/Properties of logarithms, Common
logarithms, Characteristic and Mantissa, worked examples, application of
logarithm to solve pharmaceutical problems.

 Function:
Real Valued function, Classification of real valued functions,

 Limits and continuity:


Introduction , Limit of a function, Definition of limit of a function (- 
x n a n sin
definition) ,lim nan1 , lim 1, 
xa xa 0 
UNIT–II 06Hours
 Matrices and Determinant:
Introduction matrices, Types of matrices, Operation on matrices,
Transpose of a matrix, Matrix Multiplication, Determinants, Properties of
determinants , Product of determinants, Minors and co-Factors, Adjoint
or adjugate of a square matrix , Singular and non-singular matrices,
Inverse of a matrix, Solution of system of linear of equations using matrix
method, Cramer’s rule, Characteristic equation and roots of a square
matrix, Cayley–Hamilton theorem, Application of Matrices
insolving Pharmacokinetic equations

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UNIT–III 06Hours
 Calculus
Differentiation : Introductions, Derivative of a function, Derivative of a
constant, Derivative of a product of a constant and a function ,Derivative
of the sum or difference of two functions, Derivative of the product of two
functions (productformula), Derivative of the quotient of twofunctions
(Quotient formula) –Without Proof, Derivative of xn w.r.tx, where nisany
rational number, Derivative of ex,, Derivative of loge x , Derivative of
a ,Derivative of trigonometric functions from first principles (without
x

Proof), Successive Differentiation, Conditions for a function to be a


maximum or a minimum at a point. Application

UNIT–IV 06Hours
 Analytical Geometry
Introduction: Signs of the Coordinates, Distance formula,
Straight Line : Slope or gradient of a straight line, Conditions for
parallelism and perpendicularity of two lines, Slope of a line joining two
points, Slope – intercept form of a straight line
Integration:
Introduction, Definition, Standard formulae, Rules of integration , Method of
substitution, Method of Partial fractions, Integration by parts, definite
integrals, application
UNIT-V 06Hours
 Differential Equations : Some basic definitions, Order and degree,
Equations in separable form , Homogeneous equations, Linear
Differential equations, Exact equations, Application in solving
Pharmacokinetic equations
 Laplace Transform : Introduction, Definition, Properties of Laplace
transform, Laplace Transforms of elementary functions, Inverse
Laplace transforms, Laplace transform of derivatives, Application to
solve Linear differential equations, Application in solving Chemical
kinetics and Pharmacokinetics equations

Recommended Books (Latest Edition)

1. Differential Calculus by Shanthinarayan


2. Pharmaceutical Mathematics with application to Pharmacy by
Panchaksharappa Gowda D.H.
3. Integral Calculus by Shanthinarayan
4. Remedial Mathematics, S.B. Singh, Khanna Publishing House, New Delhi.
5. Higher Engineering Mathematics by Dr.B.S.Grewal
6. Advanced Engineering Mathematics by Dr. Chandrika Prasad & Dr. Reena Garg, Khanna
Publishing House, New Delhi.

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