PROJECT REPORT - PHARMACEUTICAL FACILITY

AT
SIP, PITHAMPUR, DIST. DHAR

29.02.2024
KNEXIR CONSULTANTS PVT.
LTD. CONSULTING ENGINEERS
OBJECTIVE
 The Proposed Greenfield Formulation facility will house the following:
a. Manufacturingand packaging of :
1) Oral Solid Dosage Forms (OSD) – Tablet, Capsule , dry powder and Ointment
2) Nasal Forms
3) R&D for various Forms

b. Secondary packaging for the above.

c. Necessary support areas like inward / dispatch, warehouse, sampling, dispensing,
technical areas etc.
d. Workers amenities, change rooms, restrooms, canteen areas etc.
e. Central utilities for above manufacturing blocks
 A Quality Control Laboratory, QC office, QA office, Audit room, document storages,
Stability area, Control Sample storage area etc.
 The new facility shall be designed to meet USFDA, MHRA, EU-GMP, Russia-GMP,
TGA, Anvisa, WHO GMP .
BRIEF OF THE COMPANY

INDUSTRY : PHARMA INDUSTRY

MANUFACTURING OF PHARMACEUTICALS PRODUCTS
GENERAL PROFILE :
AND HERBAL EXTRACT.
NAME OF THE BORROWER : SAVA HEALTHCARE LIMITED
CONSTITUTION : PUBLIC LIMITED
DATE OF INCORPORATION : 21ST FEBRUARY 1989
SECTOR (PUBLIC / PRIVATE
: PUBLIC
/ JT.)
GROUP / HOUSE : SAVA GROUP
NATURE OF INDUSTRY /
: PHARMA INDUSTRY
ACTIVITY
LOCATION :
SHED NO 508 GIDC 2 WADHAWN CITY SURENDRA
REGD. OFFICE :
NAGAR-GUJARAT
CORPORATE OFFICE : SAVA HOUSE, SAKORE NAGAR. VIMAN NAGAR, PUNE
PLOT NO. 17/6, BLOCK NO. D1, MIDC CHINCHWAD,
R&D CENTER
PUNE-411019, INDIA.
SHED NO 508 GIDC 2 WADHAWN CITY SURENDRA
FACTORY (EXISTING) :
NAGAR-GUJARAT
HERBAL PLANT: - PLOT NO.107, 108,109, KIADB, III PHASE,
FACTORY (EXISTING) INDUSTRIAL AREA, MALUR-563160, KOLAR DISTRICT,
KARNATAKA INDIA.
DIRECTOR DETAILS

# Name of the Director Designation Address & Contact No Aadhar No.

Villa-55/2 Hattan Villas 388-Emirates Hill Second, 388-
Vinod Ramchandra
1 Director 1097, Premise No. 388991054, PO Box: 943292, Dubai 838856229855
Jadhav
Contact No. +91 20 30516100
E-7, Flat No.001,Rohan Mithila 2, Viman Nagar, Sanjay
Vishal Ramchandra Whole-time
2 Park Pune-411014, Maharashtra, INDIA 226948144303
Jadhav Director
Contact No. +91 20 30516100
1334, scheme No 114 Part 1, Indore Vijaya Nagar,
Director
3 Dr. Sonal Rajesh Sisodia Madhya Pradesh-452010, INDIA 412522182824
(Independent)
Contact No. +91 20 30516100

Additional Saritanagari Phase – 2

4 Ulhas Rajaram Puranik Director Bldg. E – 18, Block 7,
(Independent) Sinhagad Road,Pune– 411 030,Maharashtra, India
 DETAIL OF GROUP /GROUP PROMOTERS
Mr. Vinod Jadhav: The promoter of Sava Group is a Graduate in Mechanical Engineering, Graduate Diploma in materials Management,
and Diploma in import-export management and certificate course in excise laws. He began his career in Larsen and Toubro as Engineer,
worked as Import Export Manager for Mercedes-Benz India Ltd and Fiat India Limited and has earned an experience of 18 years.

Mr. Vinod Jadhav has rich experience and deep knowledge about the Pharmaceutical Industry and has immensely contributed to the
growth of the company by his incisive and broad-based knowledge of the domestic and international markets. Starting with a small equity
capital at the time of inception, Sava has developed into a highly successful operation in a short span of time and is amongst the fastest
growing Indian Pharmaceutical companies and worldwide operations. He has built up the brand of “SAVA” in the Pharmaceutical Industry
in a very short span of time. He has led the company from its nascent stage and has propelled its growth. In 2001, he started his own
retail pharmacy-Franchisee Medicine Shoppe Inc. USA and commenced wholesale export activity mainly to Fiji, Vanuatu islands, Malta,
Barbados & Mauritius Market.

SHL also works as a contract research and manufacturing service (CRAMS) provider for companies like Alkem Laboratories Limited, Dr
Reddy's Laboratories Limited, Lupin Pharmaceuticals Inc, Sun Pharmaceuticals Industries Limited, Cadila Healthcare Limited, etc. The Sava
group was established in the year 2003. Prior to SHL, the group had a strong presence in trading and distribution of pharmaceuticals
products through its flagship company, Anagha Pharma Private Limited (APPL). With SHL, the group has now entered into manufacturing
of pharmaceuticals products. The Sava group has its presence in more than 30 countries with its global distribution network and
marketing offices.

Experienced promoters along with established long track record of the company SHL was established in 1989. In the last 25 years, the
company has been able to establish itself in the business of manufacturing of pharmaceutical products. The current promoter of SHL
Mr. Vinod Jadhav has an experience of more than one and a half decades in the pharma sector. Being in the industry for such a long
period has helped the promoters in gaining adequate acumen about the business. Diversified geographical reach along with diversified
product portfolio SHL has presence in more than 30 countries.It has a global distributionnetwork with various marketing offices in UAE,
 DETAIL OF GROUP /GROUP PROMOTERS

Singapore, Uzbekistan, Turkmenistan, Russia, USA, African countries, Afghanistan, Thailand, Ukraine, etc. The domestic sales contribute
around 40% to the total income from operations while the rest is contributed from exports.

SHL has a wide product portfolio covering both medicines for human health and animal health. The product line of SHL under Human Life
includes pharmaceutical products like respiratory assistance, anti-diabetic, cardiovascular, urology, gastroenterology dermatology, etc,
whereas in the animal health segment, it manufacturesproducts concentratingon dogsand cats.

Accredited manufacturing facilities with well-equipped R&D facility

SHL operates one state of the art manufacturing plant at Surendranagar (Gujarat). The manufacturing unit of SHL has received
accreditation from Good Manufacturing Practices (GMP) Ukraine, Pan America Health Organization (PAHO) — USA, World Health
Organization (WHO), Kenya Pharmacy and Poison Board (PPB), Nigeria National Agency for Food and Drug Administration (NAFDAC),
Food
& Drug Administration (FDA), Russia and ISO 9001:2008, Health Canada (HC).
The company follows Total Quality Management System (TQMS) for quality check and control to ensure the quality of the product as per
the standards of the regulating authorities. Furthermore, the company is also managing a R&D Centre at Pune which mainly focuses on
the development of innovative
Formulationsacross various therapeutic segments.

The Sava group had undergone restructuring with amalgamation of Sava Healthcare Limited and Sava Private Limited into its Flagship
Company Anagha Pharma Private Limited under the judgment order of Hon’ble High Court on 17-10-2014. The name of the amalgamated
entity was also changed to Sava Healthcare Limited.
 DETAIL OF GROUP /GROUP PROMOTERS
Milestones achieved by Sava Group :

• Assured growth rate in the Pharma sector

• Higher penetration in the Domestic markets with available resources and expansion possibilities
• Higher Global network with existing nodes that ensures delivery.
• Merged entity “Sava Healthcare Ltd” +”Anagha Pharma Pvt ltd”+ ”Sava Private Ltd” will emerged joint corporate
group as to be in Top 200 Global Companies in the year 2030. by achieving >Rs.1,000 Crores Turnover.
• Reserves of Merged entities including foreign subsidiary will strengthen the internal Reserves of the company.
• Gujarat & Karnataka located plant of Sava Healthcare ltd has duly complied all necessary legal provisions of all
authorities including Good Manufacturing Practices audit (GMP) from Food & Drugs authority of India on
regular basis.
• Points to note that; Gujarat located plant of Sava Healthcare ltd has obtained Ukraine approval for
Surendranagarfinished formulation plant.
• Successful launch of Savavet division for Animal Health Division in 2012 & expected Rs35. Cr in FY2021-21 with
Own supply chain management & Brand.
• Commission of Herbal Extract at Malur having US FDA approved plant & exporting goods to USA
• New International business partner- Movi Health with consignee, Jamp pharma, Abdi Ibrahim Inc
 DETAIL OF GROUP /GROUP PROMOTERS
Milestones achieved by Sava Group :

• Pioneered and achieved “Manufacturer of Choice” reputation for Nasal Sprays in India and serving customer
base like Zydus cedilla, Dr. Reddy, Macleod’s
• DSIR recognition for Research and development for Sava healthcare Ltd helps to obtain wide range of Income tax
and other statutory tax incentives. Total 250 + product developed
• 06 new Herbal products developed & in under process to launch online market for the same

Market : US, EU, MHRA, ROW & Domestic market.

PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
PULMOLOR TABLET AMBROXOL HYDROCHLORIDE AND LORATADINE TABLETS
DICYCLOVERINE HYDROCHLORIDE AND SIMETHICONE
MOVESPASM TABLET
TABLETS
MOVINAZA 10 SERRATIOPEPTIDASE TAB 10 MG
MOVINAZA 20 SERRATIOPEPTIDASE TAB 20 MG

PARACETAMOL, CAFFEINE ANHYDROUS,

HELPEX ANTICOLD DX TABLET PHENYLEPHRINE HYDROCHLORIDE, CHLORPHENIRAMINE
MALEATE &
DEXTROMETHORPHAN HYDROBROMIDE TABLETS

PARACETAMOL,CAFFEINE ANHYDROUS,PHENYLEPHRINE
HELPEX ANTICOLD TABLET
HLC & CHLORPHENIRAMINE MALEATE TABLETS
Tablet
PULMOBREATH TAB ACETYLCYSTEINE AND AMBROXOL HYDROCHLORIDE
TABLETS
GLUCOSAMINE SULFATE, CHONDROITIN SULFATE &
MOVEX ACTIVE TAB
DICLOFENAC POTASIUM TAB
GLUCOSAMINE SULPHATE, CHONDROITIN SULPHATE
MOVEX COMFORT TAB
TABLETS
JAMP METOPROLOL L 25 MG METOPROLOL TARTRATE T USP 25 MG
JAMP METOPROLOL L 50 MG METOPROLOL TARTRATE T USP 50 MG
JAMP METOPROLOL L 100 MG METOPROLOL TARTRATE T USP 100 MG
AG- METOPROLOL L 25 MG METOPROLOL TARTRATE T USP 25 MG
AG- METOPROLOL L 50 MG METOPROLOL TARTRATE T USP 50 MG
AG- METOPROLOL L 100 MG METOPROLOL TARTRATE T USP 100MG
PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
PYRANTEL PAMOATE 125 MG TABLET PYRANTEL PAMOATE TABLETS 125 MG

JAMP LAMIVUDINE 100MG(1X100T) LAMIVUDINE TABLETS USP 100MG

JAMP LAMIVUDINE 150MG(1X60T) LAMIVUDINE TABLETS USP 150MG

JAMP LAMIVUDINE 300MG(1X30T) LAMIVUDINE TABLETS USP 300MG

EXILAR 2.5 TADALAFIL TABLETS 2.5 MG

EXILAR 5 TADALAFIL TABLETS 5 MG

EXILAR 10 TADALAFIL TABLETS 10 MG

EXILAR 20 TADALAFIL TABLETS 20 MG

Tablet
EXILAR CT 20 TADALAFIL CHEWABLE TABLETS 20 MG

SAVITRA 10 MG VARDENAFIL TABLETS 10 MG

SAVITRA 20 MG VARDENAFIL TABLETS 20 MG

SILJOY 100 SILDENAFIL CITRATE TABLETS 100 MG

SILJOY 100 PINK SILDENAFIL CITRATE TABLETS 100 MG

EXILAR MAX TAB DAPOXETINE AND TADALAFIL TABLTES

SAVITRA MAX TAB DAPOXETINE AND VARDENAFIL TABLETS

SILJOY MAX DAPOXETINE AND SILDENAFIL TABLETS

PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
FENOPAZ 10MG SOLIFENACIN SUCCINATE TABLETS 10 MG
FENOPAZ 5MG SOLIFENACIN SUCCINATE TABLETS 5 MG
ETALIZE -S 10 SIMVASTATIN AND EZETIMIBE TABLETS(10/10)
ETALIZE -S 20 SIMVASTATIN AND EZETIMIBE TABLETS(20/10)
UGINE 10 MINOXIDIL TABLETS IP 10 MG
LIPROLESS 145 MG FENOFIBRATE TABLETS 145 MG
ROZATIN 5 ROSUVASTATIN TABLETS 5 MG

Tablet ROZATIN 10 ROSUVASTATIN TABLETS 10 MG

ROZATIN 20 ROSUVASTATIN TABLETS 20 MG
ROZATIN 40 ROSUVASTATIN TABLETS 40 MG
OLMESAVA 20 OLMESARTAN MEDOXOMIL TABLETS 20MG
OLMESAVA 40 OLMESARTAN MEDOXOMIL TABLETS 40MG
PIGEON 15 PIOGLITAZONE TABLETS IP 15 MG
PIGEON 30 PIOGLITAZONE TABLETS IP 30 MG
PIGEON 45 PIOGLITAZONE TABLETS IP 45 MG
PRODUCT & PRODUCTION CAPACITY
DOSAGE
FORM PRODUCT NAME GENERIC NAME
SILOGRA 100 SILDENAFIL CITRATE TABLET 100MG
ZIMATRA 20 VARDENAFIL TABLETS 20 MG
ZIMALIS 20 TADALAFIL TABLETS USP 20 MG
SUMATRIPTAN SUMATRIPTAN USP100 MG
CIPROFLOXACIN BP CIPROFLOXACIN TABLETS BP 500 MG
ADR 75 ASPIRIN DELAYED RELEASE TABLETS USP 75 MG
NEBIBIO TAB NEBIVOLOL TABLETS 5 MG
ADR 150 ASPIRIN DELAYED RELEASE TABLETS USP 150 MG
Tablet
AMBROXOL
AMBROXOL HYDROCHLORIDE TAB
HYDROCHLORIDE TAB
BIOVAL TAB VALACYCLOVIR HYDROCHLORIDE TABLETS 500 MG
VIKAZID TAB 150 MEBENDAZOLE AND PYRANTEL PAMOATE TABLETS
NEBIBIO H TAB NEBIVOLOL & HYDROCHLOROTHIAZIDE TABLETS
LOSARTAN POTASSIUM TAB LOSARTAN POTASSIUM TABLETS 50 MG
AZIBIO 500 AZITHROMYCIN TABLETS 500 MG
ERECOR 100 SILDENAFIL CITRATE TABLET 100MG
PRODUCT & PRODUCTION CAPACITY

DOSAGE
FORM PRODUCT NAME GENERIC NAME
HOVID ROSUVASTATIN 10mg ROSUVASTATIN TABLETS 10 MG
HOVID ROSUVASTATIN 20mg ROSUVASTATIN TABLETS 20 MG
BIOCLOPI TAB CLOPIDOGREL TABLETS USP 75 MG
LORA 50 TAB LOSARTAN POTASSIUM TABLETS 50 MG
ACECLODEAL TAB ACECLOFENAC TABLETS 100 MG
LIPSAVA 20 ATORVASTATIN TABLET 20 MG
MOXI BIO TAB MOXIFLOXACIN TABLETS
Tablet LEVOHISTA TAB LEVOCETIRIZINE DIHYDROCHLORIDE TABLETS
BIOCAR 40 TELMISARTAN TABLETS 40 MG
Biotor 10 ATORVASTATIN TABLETS 10 MG
Biotor 20 ATORVASTATIN TABLETS 20 MG

Clarithromycin USP(Ulceron kit) Clarithromycin USP TAB

TINIDAZOLE TAB(Ulceron kit) TINIDAZOLE TAB

PRODUCT & PRODUCTION CAPACITY

DOSAGE FORM PRODUCT NAME GENERIC NAME

ANXIOSTAR 30 CAP DULOXETINE HYDROCHLORIDE CAPSULES 30 MG

ANXIOSTAR 60 CAP DULOXETINE HYDROCHLORIDE CAPSULES 60 MG

COXIBEST 200 CAP CELECOXIB CAPSULES 200 MG

ZAMOCAL 120 ORLISTAT CAPSULES 120 MG

LANSOPRAZOLE DELAYED
LANSOPRAZOLE DELAYED RELEASE CAPSULES USP
RELEASE CAP

PARACETAMOL, PHENYLEPHERINE HCL &

BIOFLU CAPSULES
Capsule CHLORPHENIRAMINE MALEATE CAPSULES

BOI-ITRA CAP ITRACONAZOLE CAP

BIO USRO CAPSULES 300mg URSODIOL CAPSULES USP 300 MG

FLUXETYL CAPSULES FLUOXETINE CAPSULES USP 20 MG

BIOCERIN CAP DIACEREIN CAPSULES 50 MG

BIOTRATE CAP MULTIVITAMIN CAPSULES WITH ZINC AND CHROMIUM

PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
AMBROXOL HYDROCHLORIDE & LORATADINE POWDER
PULMOLOR POWDER
FOR ORAL SUSPENSION

EMOLAX POLYETHYLENE GLYCOL 3350 POWDER FOR ORAL SOLUTION

Oral Powder
JAMP CALCIUM POLYSTYRENE
CALCIUM POLYSTYRENE SULFONATE POWDER
SULFONATE POWDER

JAMP SODIUM POLYSTYRENE SULFONATE SODIUM POLYSTYRENE SULFONATE POWDER

PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
DESMOPRESSIN INTRANASAL SOLUTION BP DESMOPRESSIN ACETATE BP
FLUTICASONE PROPIONATE [MICRONISED]
FLUTICASONE NASAL SPRAY BP BP

FLUTICASONE PROPIONATE [MICRONISED]

FLUTICASONE PROPIONATE NASAL SPRAY BP
FLUTICASONE PROPIONATE [MICRONISED]
FLUTICASONE PROPIONATE NASAL SPRAY BP
FLUTICASONE PROPIONATE [MICRONISED]
FLUTICASONE PROPIONATE NASAL SPRAY BP
FLUTICASONE PROPIONATE [MICRONISED]
FLUTICASONE NASAL SPRAY BP BP
Nasal Spray MOMETASONE AQUEOUS NASAL SPRAY BP MOMETASONE FUROATE [MICRONISED] BP

MOMETASONE AQUEOUS NASAL SPRAY BP MOMETASONE FUROATE [MICRONISED] BP

MOMETASONE AQUEOUS NASAL SPRAY BP MOMETASONE FUROATE [MICRONISED] BP

DESMOPRESSIN INTRANASAL SOLUTION BP DESMOPRESSIN ACETATE BP
XYLOMETAZOLINE NASAL DROPS BP0.05%W/V XYLOMETAZOLINE HYDROCHLORIDE BP

XYLOMETAZOLINE NASAL DROPS BP0.1%W/V XYLOMETAZOLINE HYDROCHLORIDE BP

XYLOMETAZOLINE NASAL SPRAY 0.1%W/V XYLOMETAZOLINE HYDROCHLORIDE BP

XYLOMETAZOLINE HYDROCHLORIDE NASAL SOLUTION
XYLOMETAZOLINE HYDROCHLORIDE USP
USP 0.05%W/V
PRODUCT & PRODUCTION CAPACITY

DOSAGE FORM PRODUCT NAME GENERIC NAME

XYLOMETAZOLINE HYDROCHLORIDE
XYLOMETAZOLINE HYDROCHLORIDE USP
NASAL SOLUTION USP 0.1%W/V

SALINE NASAL SOLUTION SODIUM CHLORIDE BP

XYLOMETAZOLINE NASAL SPRAY 0.05%W/V XYLOMETAZOLINE HYDROCHLORIDE BP

Nasal Spray XYLOMETAZOLINE NASAL SPRAY 0.1%W/V XYLOMETAZOLINE HYDROCHLORIDE BP

FLUTICASONE FUROATE NASAL SPRAY FLUTICASONE FUROATE IH

ZOLMITRIPTAN NASAL SPRAY ZOLMITRIPTAN IH

AZELASTINE HYDROCHLORIDE NASAL SPRAY AZELASTINE HYDROCHLORIDE BP

PRODUCT & PRODUCTION CAPACITY
DOSAGE FORM PRODUCT NAME GENERIC NAME
MENTHOL,CAMPHOR,THYMOL,METHYL
HELPEX EFFECT OINTMENT SALICYLATE,EUCALYPTUS OIL,TURPENTINE
OIL OINTMENT

DICLOFENAC DIETHYLAMINE,LINSEED OIL,

D'END GEL
METHYL SALICYLATE AND MENTHOL GEL

DOCTRINE CREAM LIDOCAINE AND PRILOCAINE CREAM USP

Topical SILJOY JELLY CHLORHEXIDINE GLUCONATE JELLY

SILVER SULPHADIAZINE WITH
SALBESAN CREAM
CHLORHEXIDINE CREAM
CLOTRIMAZOLE, BECLOMETHAZONE
BECLOGEN CREAM
AND GENTAMYCIN CREAM
KETO CON CREAM KETOCONAZOLE CREAM 2 % W/W
BIO-CLO CREAM CLOBETSOLECREAM BP0.05%
COST OF PROJECT & MEANS OF FINANCE ( To be Updated )
(Rs. in Lakhs)
S. No. Particulars Amount

A Cost of Project

1 Land
2 Building 13,378.00
3 Plant and Machinery 8,500.00
4 Electrical Installation 1,200.00
5 Furniture and Fixture 420.00
6 Office Equipments
7 Others
Total 23,498.00

B Means of Finance

1 Share Capital
2 Term Loan
3 Internal Accruals
Total
3D VIEW
SITE MASTER PLAN

Plot Plan
OSD – GROUND FLOOR PLAN

Ground Floor -
OSD
OSD – FIRST FLOOR PLAN

First Floor - OSD

OSD – SECOND FLOOR PLAN

Second Floor -
OSD
OSD – SECTIONS

Sections - OSD
NASAL GROUND FLOOR PLAN

Nasal - Ground
Floor
NASAL PLAN AT 5M LEVEL

Nasal Plan - 5M
Level
NASAL PLAN AT 9M LEVEL

Nasal Plan at 9M
Level
NASAL - SECTIONS

Nasal Sections
ADMIN, CANTEEN,QA,QC AND R & D – FLOOR PLANS

Admin, Canteen,
QA,QC and R &D
ADMIN, CANTEEN,QA,QC AND R & D – SECTIONS

Sections
AREA STATEMENT

GROUND FIRST THIRD TOTAL MAX. HT.

S. NO. SECOND FLOOR BUILT-UP OF
AREA DESCRIPTION FLOOR FLOOR FLOOR AREA AREA STRUCTURE
AREA AREA AREA IN M.
1
OSD BLOCK (GENERAL 12917.00
2 16M
NASAL BLOCK 3257.00 1447.00 6599.00
3 1895.00
ADMIN,QC,QA,CANTEEN & 13M
R& D 1530.00 1530.00 1530.00 1530.00 6120.00
20M
4 SECURITY & OHC 143.10 143.10
5 UTILITY 510.00 510.00 240.00 1260.00 4.75M
6 PUMP ROOM 250.00 250.00 19.5M
7 TANK FARM 453.00 453.00 9.00M
8 ETP 542.00 542.00
9 SECURITY -1 36.00 36.00
TOTAL GROUND FLOOR
11874.10 TOTAL BULIT-UP AREA = 28320.10
BUILT-UP AREA =
Process equipment list - OSD
BLOCK-B (GENERAL - HUMAN)
Sr. No. FINISHED DOSAGE
PROCESS PARTICULAR EQUIP. CAP.
FORM
RMG 300 lit
Granulation-1 FBD 300 lit
Blender 1200 lit
RMG 50 lit
Granulation-2 FBD 50 lit
Blender 100 lit
Dry Granulation Blender 500 lit
Press-1 (37 Station,
37 station
interchang)
Compression
Press- 2 (37 Station,
37 station
interchang)
Blender 300 lit
1 Tablets and Capsule General Capsule
Capsule filling machine 90,000

Coater 48 and 36 inch 100 kg

Coating
Coater 30 and 24 inch 30 kg

Tablet Inspection Tb. Inspection M/C 2,00,000 TPH

Blister-1 100 BPM
Blistering
Blister-2 100 BPM
Counting, Filling &
Bottle Pack 60 BPM
Labelling
Sachet ( 2g to 150 g) Sachet Filling M/C 80 SPM
Process equipment list - OSD
Sr. No.
FINISHED DOSAGE
PROCESS PARTICULAR EQUIP. CAP.
FORM

Cartonator-1 ( Blister-1)
100CPM

Cartonator-2 ( Blister-2)
100CPM
Catonator & Priniting
Cartonator-3 ( Bottle
60 BPM
Pack)
Cartonator-4 ( Sachet
80 SPM
pack)
Shrik pack machine 60 PPM
1 Tablets and Capsule Shrink Machine
Shrik pack machine 60 PPM
Barcoder -1 100CPM
Barcoder -2 100CPM
Bar Coding
Barcoder -3 80CPM
Barcoder -4 80CPM
Case Packer-1 10 CPPM
Case Packer-2 10 CPPM
Case Packers
Case Packer-3 10 CPPM
Case Packer-4 10 CPPM
Process equipment list - OSD
Sr. No. FINISHED DOSAGE EQUIP.
PROCESS PARTICULAR
FORM CAP.
Shifter & Blender
2000 lit
Gravity Feed system
35 kg
Dry powder oral Bottle Filling, Labelling &
2 Suspension Packing Filling & Labelling 60 BPM
Cartonator-1 60CPM
Barcoder -1 60CPM
Case Packer-1 10CPPM
Phase -1 Vessel
500 lit
Phase -2 Vessel
500 lit
Manufacturing Solution Preparation
External Creams / Vessel
150 lit
3 ointments / gels Mixing Vessel (CIP
(general) System) 750 lit
Holding Vessels 600 lit
Filling Tube Filling 75 TPM
Catonator Cartonator-1 75 CPM
Bar Coding Barcoder -1 75 CPM
Case Packers Case Packer-1 10 CPPM
Process equipment list - NASAL
BLOCK-C (RESPIRATORY - HUMAN)
FINISHED DOSAGE EQUIP.
SR. NO. PROCESS PARTICULAR
FORM CAP.
NASAL SPRAY - LINE-1
Manufactuing Vessel -1 1000
Manufactuing Vessel -2 1000
Manufactuing Vessel -3 50
Solution Preparation Vessel-1
Manufacturing / Compounding 100
(

Solution Preparation Vessel-2 100

Solution Preparation Vessel-3 25

Holding Vessel -1 1000
Holding Vessel -2 200
1 NASAL SPRAY Holding Vessel -3 50

Filtration & Holding CIP and SIP System ( 3 No.) 3

Inline Filtration Cyctem ( 3
No.) 3

Filter Integrity tester ( 3 No.) 3

DubbleDoor Steam sterilizer (
Steam sterilizer 1000 lit
1 No.)
Air rinsing M/C (Plastic vials)) 125
Vials Washing & Sterilization Glass Visal washing M/C 125
Depyrogentation Tunnel 125
Process equipment list - NASAL

SR. FINISHED
PROCESS PARTICULAR EQUIP. CAP.
NO. DOSAGE FORM
NASAL SPRAY - LINE-1
Nasal filling and sealing M/C 125
Filling& Sealing
Checkweighing System 125
1 NASAL SPRAY Inspection Vial Inspection System
System 125
Labelling M/C (with Vision
system) 125
Auto-Cartonator (with Vision
Labeling & system) 125
Packing Security seal placing M/C 125
Barcoding machine 125
Bundler / Shrink wrapper 25
Case Packers 10
Process equipment list - NASAL
FINISHED DOSAGE
SR. NO. PROCESS PARTICULAR EQUIP. CAP.
FORM
NASAL SPRAY -LINE-2 ( FUTURE PROVISION)
Manufactuing Vessel -1 1000
Manufacturing / Manufactuing Vessel -2 1000
Compounding Solution Preparation Vessel-1 ( HS) 100
Solution Preparation Vessel-2 100
Holding Vessel -1 1000
1 Holding Vessel -2 200
NASAL SPRAY
Filtration & Holding CIP and SIP System ( 2 No.) NA
Inline Filtration Cyctem ( 2 No.) NA
Filter Integrity tester ( 2 No.) NA
Steam sterilizer Dubble Door Steam sterilizer ( 1 No.) 1000 lit
Air rinsing M/C (Plastic vials)) 240
Vials Washing & Glass Visal washing M/C
240
Sterilization
Depyrogentation Tunnel 240
Nasal filling and sealing M/C 240
Filling& Sealing Checkweighing System 240
Inspection System Vial Inspection System 240
Labelling M/C (with Vision system) 240
Auto-Cartonator (with Vision system) 240
Security seal placing M/C 240
Labeling & Packing Barcoding machine
240
Bundler / Shrink wrapper 30
Case Packers 10
Process equipment list - NASAL

SR. NO. FINISHED DOSAGE FORM PROCESS PARTICULAR EQUIP. CAP.

FUTURE - PROVISION
Blending 1 80 lit
Blending 2 25 lit
Manufacturing
Highshare mixing 25 lit
Micronization 10
Capsule filling machine 90,000
Filling
Cartrage filling 60
Capsule Inspection Capsule Inspection M/C 100000
Counting, Filling & Labelling 80
Packing
Cartrage packing & Labelling 60
Auto-Cartonator (with Vision system)
DRY POWDER FOR 80
-01
2 INHALATION
(Future DPI) Auto-Cartonator (with Vision system)
-02 60
Security seal placing M/C -01 80
Security seal placing M/C -02 60
Barcoding machine-01 80
Labeling & Packing
Barcoding machine-02 60

Bundler / Shrink wrapper -01 30

Bundler / Shrink wrapper -02 25

Case Packers-01 10
Case Packers-02 10
Process equipment list –R & D (Analytical Development )
Sr No LAB NAME AREA NAME AREA (SFT)
1 Glassware wash
WASH 200
2 Glassware Storage
3 Balance room WEIGH 150
4 Disposal room
OTHERS 100
5 Hot room
6 Documentation Storage DOC 600
7 Wet lab wash area
8 Wet lab1 WET 600
9 Wet lab2
10 Disso Lab DISSO 600
11 HPLC Lab 1
HPLC 1000
12 HPLC Lab 2
13 Inhalation Testing lab
INHALATION 800
14 Inhalation Characterization lab
15 GC Prep room
GC 200
16 GC Lab
17 Future expansion area EXPANSION 200
18 Office Space OFFICE 800
19 Analytical Store STORE 300
20 Stability Cell STABILITY 800
Process equipment list –R & D – F & D (New)
Sr No EQUIPMENT NAME SECTION AREA NEEDED (SFT)

1 Hand Filling Capsule Machine (Size 00,0,1,2) CAPSULE/DPI

2 Hand Filling Capsule Machine (Size 1, 2, 3 & 4) CAPSULE/DPI
3 Automatic Capsule Filling Machine CAPSULE/DPI
4 Dust Collector CAPSULE/DPI
5 M-DPI capsule filling machine CAPSULE/DPI 500
6 Cyclomixer CAPSULE/DPI
7 Alphie three-dimensional mixer CAPSULE/DPI
8 MIDAS MICRONIZER CAPSULE/DPI
9 Electronic Balance CAPSULE/DPI
10 R&D Documentation Storage + DQA DOCUMENTATION 400
11 Office Space OFFICE 1200
12 Brookfield Viscometer DV-1 RV IPQC
13 pH Meter IPQC
14 Friabilator IPQC
15 Moisture Analyzer IPQC
16 Vernier Caliper (Dial Type) IPQC 300
17 Vernier Caliper (Digital Type) IPQC
18 Tablet Hardness Tester IPQC
19 Tablet Hardness Tester IPQC
20 Disintegration Tester IPQC
Process equipment list –R & D
Sr No EQUIPMENT NAME SECTION AREA NEEDED (SFT)

21 High Shear Stirrers LIQUID/SS

22 Vacuum Pump LIQUID/SS
23 Water bath LIQUID/SS
24 ROPP Cap Sealing Machine LIQUID/SS
25 Hot Plate LIQUID/SS
26 Crimping Machine LIQUID/SS
600
27 Homogenizers/Dispersers LIQUID/SS
28 Homogenizers/Dispersers LIQUID/SS
29 Lab Stirrer LIQUID/SS
30 Lab Stirrer LIQUID/SS
31 Lab Stirrer LIQUID/SS
32 Electronic Balance max-50 kg & min- 500 gm LIQUID/SS
33 Blister Packaging Machine PACKAGING
34 Electromagnetic Induction Sealing Machine PACKAGING
300
35 Leak Tester PACKAGING
36 Super Seal Machine PACKAGING
37 Roller Compactor TABLET
38 Multimill (Standard) TABLET
1200
39 Vibro Sifter Machine TABLET
40 Mixer Grinder TABLET
Process equipment list –R & D
Sr No EQUIPMENT NAME SECTION AREA NEEDED (SFT)

41 Kalveka Blender TABLET

42 Tray Dryer (Oven) TABLET
43 Fluid Bed Dryer & Processor TABLET
44 Rapid Mixer Granulator TABLET
45 Retsch Rapid Dryer TABLET
46 Tablet Compression Tablet (9 station) TABLET
47 Dust Collector TABLET
48 Tablet Compression Tablet (16 station tooling) TABLET
1200
49 Colloid Mill TABLET
50 Auto Coating Machine TABLET
51 Quadro comill TABLET
52 Kenwood mixer TABLET
53 Toolings and Spare Parts TABLET
54 Portable Dehumidifier TABLET
55 Electronic Balance small TABLET
56 Electronic Balance Kgs TABLET
57 Washing Area WASH
300
58 Clean Equipment Area WASH
59 Hot Melt Extruder EXPANSION
60 Spray dryer EXPANSION 400
61 High speed Granulator EXPANSION
62 API STORE WH
63 RM STORE WH
64 PM STORE WH
65 RLD STORE WH 1000
66 DISPENSING WH
67 Spareparts/Change parts and others WH
68 FG STORE WH
POWER REQUIREMENTS ( To be Updated)

ELECTRICAL LOAD LIST

Maximum
Connected Working Future Stand-By Diversity
Sr. Area Description Demand Remark
Load (kW) Load (kW) Load (kW) Load (kW) Factor (kW)
1 HVAC Load 875.00 875.00 0.00 0.00 0.75 656.3
2 Process Load-OSD 627.05 627.05 0.00 0.00 0.45 282.2
3 Process Load-Nasal 194.60 194.60 0.00 0.00 0.45 87.6
4 Utility Load 1790.00 1122.00 0.00 668.00 0.75 841.5
5 Lighting Load 160.0 160.00 0.00 0.00 0.75 120.0
6 General Power 75.0 75.00 0.00 0.00 0.50 37.5
7 Fire Load 282.0 282.00 0.00 0.00 0.20 56.4 Assumed
8 ETP Load 50.0 50.00 0.00 0.00 0.50 25.0 Assumed

New Total 4053.6 3385.6 0.0 668.0 2106.4

 POWER REQUIREMENTS ( To be Updated)
Maximum demand in
1) = 2106 kW
KW
Maximum demand in KVA considering 0.9 power
2) = 2340 kVA
factor
Electrical Load capacity in KVA considering 80%
3) = 2926 kVA
loading
Standard Transformer
= 3000 New
4) rating kVA
% Loading on Selected Transformer
5) = 78 %
rating
DG Set - For 100% Back
6)
Up
Maximum demand in KVA for DG set considering
6.1) = 2633 kVA
0.8 power factor
DG Capacity considering
6.2) = 3098 kVA
85% loading
Standard DG rating
= 3000 2 x 1500 New
6.3) Selected kVA
% loading on Selected
6.4) = 88 %
DG rating
WATER REQUIREMENTS

Water KL/day Water Consumption KL/day

Source
MPIDC 193 KLD Domestic Purpose For canteen/ wash,
Water - Potable water general etc.
(300 employees 300*0.045=13.5 KLD
*0.045 KL)
- Ancillary (Canteen, Cooling Tower=133
Washing, General KLD
etc.) Boiler= 11.52 KLD
Industrial Purpose Manufacturing Process
- Cooling OSD Block= 6.43 KLD
- Boiler Purified Water & 16.8
- Manufacturing KLD Process Water
Process NASAL Block= 4.15
KLD Purified Water &
7.5 KLD Process Water
WAREHOUSE PALLET QTY SUMMARY

OSD-
Sr. Inventory level in NASAL
Warehouse Tablet/Capsule/J Ointment Total
No. no. of days spray
ar/Sachet
1 RM 60 1358 90 372 1501

2 PPM –AC / 120 1266 97

NON AC 300 541

3 SPM 45 200 66 372 622

4 FG 30 707 49 375 989

Total 3531 302 1419 5252

MATERIAL DISPENSING FLOWCHART
 Material handling system – Gravity Feeding for Tablet

Dispensed Mate rial W e t Granualtion ( R M G w ith C omill Blending T a b le t T a b le t Coated

material shift ing & FBP compression Coating T a b le t

Inspected Tablet for Granules Blended Granules

T a b let Blistering
Inspection
Uncoated Tablet
Blister Strip Empty Carton
Inspected Tablet Strip in Carton

Blister Foil T a ble t Blister M a c h i n e Cartooning along with Checkweigher Filled carton in
shipper
Mate rial Tablet
Wet Granulation (RMG& FBD)material T ablet
Sifting Compression
transfer through vacuum system . Coating
 Empty Carton
Empty Capsule Filled Capsule C a p s ule Blister Strip
Blistering

Dispensed Material Blending Capsule Filing, Polishing and on line Inspection Capsule Blistering Cartooning along with
material Sifting Checkweigher

Blister Strip in
Carton Filled Carton in
shipper
WEIGHING / DISPENSING
 PACKING M/C

SHIPPER PACKING MACHINE

BLISTER PACKING MACHINE

Several types of pre-formed
plastic packaging used for pharmaceuticals

CARTONER MACHINE

SHRINK PACKING MACHINE

Basis of estimate and assumptions

 For building works, the cost estimate is worked out on basis of rate per sq. metre
of constructed area.
 Basic Rates Considered for Cement -Rs 300/-, Reinforcement Steel is Rs
58000/MT, Structural Steel is Rs 63000/MT (SALE/ TATA/ RINL Make)
 For building works, the cost estimate is worked out on basis of rate per sq. metre
of constructed area.
 For infrastructural works like earthwork, roads, drains, etc., the cost estimate is
worked out on the basis of rate per cu. metre, rate per sq. metre, rate per
running metre respectively as applicable.
Basis of estimate and assumptions
 All HVAC costs have been based on cost per ton of chilling or cost per cfm of
ventilation as applicable.
 Electrical panels, distribution network, lighting etc. is based on power connected
or as a percentage of equipment cost.
 The cost does not include statutory payments to be made to SEB, MIDC, DISH,
etc.
 Cost of utility equipment is worked out on cost of individual equipment for which
data is available in our data bank based on offers /orders for individual
equipment.
 Process and utility piping, instrumentation and distribution network costs are
worked out as a percentage of utility equipment costs.
Summary of Cost Statement (To be Updated)

Sr. No. Description Amt in Remarks

( Lacs )
1 Cost of Civil Works
1.1 - Infrastructure 1,035.00
1.2 - Manufacturing Plant 7,125.00
1.3 - Other Buildings 480.00
Total for Civil Works 8,640.00
2 Cost of Mechanical & Utility 2,797.00
3 Cost of HVAC works 1,510.00
4 Cost of Electrical works 1,200.00
5 Cost of Fire Fighting System 286.00
6 Cost of Office Furniture 135.00
7 Cost of Laboratory Furniture 285.00
8 Cost of Miscellaneous Equipment 145.00
Summary of Cost Statement

Sr. No. Description Amt in Remarks

( Lacs )
9 Cost of Landscaping Extra
Cost of Process equipment and QC 8,500.00 By SAVA
10
equipment
11 Statutory Approvals By
12 Consultancy & Project management @ SAVA
% BY
13 Contingencies @ +/- SAVA
14 Pre-operative Expenses @%
Total 23,498.00

General Assumptions:
* The above cost is preliminary and may vary +-20% -.
* The above cost is excluding Taxes Like GST or any other applicable
taxes. * The Above Estimate is within the battery limit of the plot.
THANK YOU……………………….

Office Address:
Empire Plaza, Building B, 1 st Floor,
Near Gandhinagar Junction,
Vikhroli (W), Mumbai 400083.

Board Line Number:

Tel. : 91 22 61547800
Mob : 7738377656, 7738377633

Email Address:
[email protected]

Website:
www.knexir.in