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    CH 27

    Uploaded by

    4brbcqxhck

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    CH 27

    Uploaded by

    4brbcqxhck
    4 views3 pages

    Original Title

    Ch27

    Copyright

    © © All Rights Reserved

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    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    4 views3 pages

    CH 27

    Uploaded by

    4brbcqxhck

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    TVanscrimtim

    T sYsthesis of mRNH 7 Occur in nuleus

    IneDNAdoublehelix unwindsDHydronbondbreak
    ①
    ctranscribedd
    →

    RNAPoymeraselenyme ) binds toarlgionoftheDNH


    → emplate Strand -

    Syuthlsis mRNH
    loding Strand -
    Donot transcribe
    7
    T DU

    ② Free RNAmucleotides Pairwith theirComplementary base CTemplatestrand )


    → Following the rules of complementary base
    pairing
    Strandrewinds 由
    ③ DNA
    → reformthe double heliy 了 bases onmRNA _
    Codon

    Tranblation
    →
    synthesis of a
    polypeptide mh an aminoacid sequence
    了 binding site

    等毁
    :
    ribosomes in cytoplasm
    _

    →
    lspecrfic aminoacid )

    → rlquire transferR1 AltRNHJ


    twm
    ① mRNAbindtoribosome π unpuirbases
    → tRNA bind with Start Codon
    UAClcomhementaryantilodon )

    ② aminoucidjoinedtgtby
    bond
    peptide
    ③ fittRNHisreleased ③
    近 Growingpolypeptide
    θ
    ④ Ribosome Vlnch a stopcodon Q
    on mRNH ④
    X
    女

    correshonding tRNA
    山
    艹
    Mubation
    ① ②
    多

    1
    少

    少 onllmore 複製
    basls
    轉
    換
    ( Replace )
    轉 位

    Sickle Cell - a aemn da Non _ disjunction不分重現象


    古 Substitution ofone baseingene DHomologous Chromosome fail tu
    Seperate during meiosis
    How -

    sickleShaned → SBter Chromatids fail o seperate meiosisII


    D

    abnormal @
    na wglobinform longfibres with KBo
    Downsyndrome
    → less efficient in carrying Or han hormal
    blood flow
    RBo 女 3 opies oflhrrmosomerlCtribomy )
    → Teud toticktgt , Prevent wrmal
    D organ damage
    → Shortur lifespan than kBo
    D unaemia
    工
    Causeof mutations
    Induced mutation誘發 Spontanlous mutation 發
    Dmutagens Dnaturany & randomly
    Dchemical lradiation
    自

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