Hyperplasia: Cortisol

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☆ cortical hyperplasia

cortisol : ACTH :

Cushing
Can 4) I nodules *

cortex
cortical cells in colours
Round ,
small nuclei

pinkish cytoplasm but i lipids


=

hyperplasia of adrenal cortex


Defined ,
well encapsulated
-

⑨ cortex

Benign

µÑN cortical lens

cells i lipid change near


granulosa ?

Elaborates :
aldosterone

Mrm : wishing


☆ ⑦ neurosis , nuclear debris

c) invasion daman
,
surrounding
on haole the
*em

f
outside

Tumor cells :

big large pin Kirsh cytoplasm


-

small nuclei

salt t
pepper chromatin pattern
-

1 stippled chromatin)
-

cells are not UNIFORM pasay


Tumor cells
> arranged in balls / rests
>
from chroma ffih Ahs
>
surrounded my
Fibro

☆ Zell baton patter


diffuse simple goiter = 1 >
Fibrous capsule
:
nodules

multimodal ar = more hehe >


follicles i irritation HUT

>
SCALLOPING COLLOID


= Actively
absorbing
colloid to

produce
>
normal Tt and 1-3
thyroid
↑ Bts
hormones
dlt Blt
stimulation

causes :


↓ iodine

drug exposure

f) or
atopic FOLLICLES

parenchyma :
forms nodules
:
MULTI NODULAR

thin fibrous connective tse


HMPHOID 0Eur
Thyroid tells replaced I

↓ small hound
cells
7
LYMPHOID NODULE / Four UE tge

↓ Lymphocytic infiltration dlttmutio

Pale germinal center

thmnd Follicle

-
lined by Follicular cells

rounded i ↓ / no colloid

MOM
µ
Autoimmune = auto antibodies
1- cell
injury
=

Get mediated)

Follicular cells
cytoplasm :
enlarged ,

pink / eosinophilic
granular material
↳ not ④ ushant
cuboidal or


columnar

*
ur
www.pvt#-METAPLAsnc ↓
CHAN WE

@ sites c-
Be
ongoing
a

:
thin tumours capsule intact

i thyroid Follicles

tumor oEhs↓
Follicular cells
: not lining Follicles

:
seen in paws / crowded
Patterns
i.

: ↑ #

bound by intact capsule


r

TUMN round cells round nuclei


'

salt is pepper appearance

Deposition of amyloid
↳ special stain :

Congo red

C cells or Paratolli altar


=
can elaborate calcitonin

Apple green infringement


-
BENIGN
↳ can erode bone
=
nearby +

can include
optic chiasm
-
Macro more than
-
Micro less than 10m
-

Most common :
Prolactinoma

Tumor cells :
not clear ; pink (eosinophil
E) Lines ; I lymphocytes
↓ around vascular
↓ channels
fibrovascular
channels

o 0
:
Most common

Follicular cells multiple layers


:
:

: nuclei =
orphan annie /
ground glass

i intranuclear
etc
grooves ,

i.
women , 40 yo .
MALIGNANT
G) Skeletal muscle
:

presume of invasion

tumor cells :

capsule :
C) hemorrhage
CT
4) invasion + breaching outside surrounding
Doc B notes :

'

thin capsule
C) multiple modules

Parathyroid 14 )mg¥¥

chief cells +

oxyphil

4) granules in
chief cells =

Hormone : PTH
↓ ↳ regulate
61T calcium
bone (↑ amt When
kidney ↓ Ca)

)
Tumor cels ( chief cells
-
round shape +

nuclei
clear cytoplasm
-

" "
FRIED E66
appearance ☆
1- distinct sa
Kanga

Moans ,
groans ,

↳ hypercalcemia

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