Blood Case Studies (Hematology)

Each group will examine one of the cases

on the slides and determine the diagnosis.

Compare the normal values with the

patients. Use a highlighter to indicate
values that are outside the normal range.

Be prepared to share your diagnosis with

the class and your reasoning for that
diagnosis.
Patient: Normal WBC = white blood cell, RBC = red blood cell,
Hb = hemoglobin, HCT = hematocrit, PLT = platelets

CBC Patient Value Normal Range

WBCs 5.5 K/uL 4.5-11 K/uL

RBCs 4.5 million/uL 3.5-5.5 million/uL

Hb 15.6 g/dL 13 - 18 g/dL

HCT 48% 45% to 52%

PLTs 200 K/uL 150-400 K/uL

Neutrophils 45% 40-69%

Lymphocytes 24% 20-40%

Monocytes 2.8% 2-8%

Eosinophils 1.2% 1-4% Patients will have one of the following conditions:
Sickle Cell Anemia, Mononucleosis, Iron deficient
Basophils .75% .5 - 1%
Anemia, Allergies, Malaria, Leukemia (cancer)
Presence of specific white
Cell Name Function
blood cells are also shown,
Red Blood Cell Carries oxygen gas from lungs to the tissues.
which may provide clues to
the patient’s condition. White Blood Cell Immune function (several types)

Neutrophil Attacks Bacteria through phagocytosis

Eosinophil Attacks parasites and can be present in

response to allergies

Basophil Active in injury sites. Releases heparin to

prevent clotting & histamines to increase
inflammation

Monocyte Initiates immune response to viruses

Lymphocyte Involved in attacking viruses & abnormal

tissues

Platelets Initiates clotting process

Patient: Betty (40, female)
She presents with symptoms of difficulty breathing on exertion, CBC Patient Value Normal Range
fatigue for past 2 to 3 months. The patient has recently switched
to a vegan diet. Upon physical Examination , other than pallor RBCs 3.0 million/uL 3.5-5.5 million/uL
(pale skin), no significant physical findings were noted.
· Hb 11.2 g/dL 13 - 18 g/dL

· HCT 45% 45% to 52%

PLTs 200 K/uL 150-400 K/uL

WBCs 9.5 K/uL 4.5-11 K/uL

· N 66 % 40-69%

· L 23 % 20-40%

· M 7% 2-8%

· E 3.4 % 1-4%

· B .6 % .5 - 1%

Diagnosis:
Patient: Teddy (23, male)
Over the past week noted increasing fatigue, sore CBC Patient Value Normal Range

throat, earaches, headaches, and episodic fever and

RBCs 5.25 million/uL 3.5-5.5 million/uL
chills. Upon physical examination we noted redness of
the throat and tonsils along with swollen lymph nodes. · Hb 15.4 g/dL 13 - 18 g/dL

· HCT 46% 45% to 52%

PLTs 155 K/uL 150-400 K/uL

WBCs 9.5 K/uL 4.5-11 K/uL

· N 24 % 40-69%

· L 73 % 20-40%

· M 0.5 % 2-8%

· E 3% 1-4%

· B 0..5 % .5 - 1%

Diagnosis:
Patient: Freddy (18, male)
CBC Patient Value Normal Range
18 year old male student from Nigeria. Came to the
emergency room with symptoms of fever, shaking RBCs 3.55 million/uL 3.5-5.5 million/uL
chills, nausea, and generalized malaise; occurring
intermittently over the past five days. Fever of 103.3°F. · Hb 5.6 g/dL 13 - 18 g/dL
Tachycardia with a heart rate of 122.
· HCT 34% 45% to 52%

PLTs 200 K/uL 150-400 K/uL

WBCs 7.5 K/uL 4.5-11 K/uL

· N 65 % 40-69%

· L 25 % 20-40%

· M 2% 2-8%

· E 7.3 % 1-4%

· B 0.7 % .5 - 1%

Diagnosis:
Patient: Benny (51, male)
CBC Patient Value Normal Range
Benny is seen by local physician for routine
preoperative exam prior to dental surgery. He is found RBCs 2.5 million/uL 3.5-5.5 million/uL
a large left upper quadrant mass. His physical exam
revealed splenomegaly. · Hb 14.7 g/dL 13 - 18 g/dL

· HCT 44 % 45% to 52%

PLTs 260 K/uL 150-400 K/uL

WBCs 9.3 K/uL 4.5-11 K/uL

· N 42 % 40-69%

· L 46 % 20-40%

· M 10 % 2-8%

· E 1.4 % 1-4%

· B 0.6 % .5 - 1%

Diagnosis:
Patient: Penny (1 year old, female)
CBC Patient Value Normal Range
Penny is an African-American girl who was referred to
a doctor for lethargy and pale skin. Penny is RBCs 3.3 million/uL 3.5-5.5 million/uL
breastfed and takes infant formula with iron and is
eating foods like rice and vegetables. Physical exam · Hb 10.4 g/dL 13 - 18 g/dL
reveals splenomegaly.
· HCT 30 % 45% to 52%

PLTs 210 K/uL 150-400 K/uL

WBCs 7.5 K/uL 4.5-11 K/uL

· N 61 % 40-69%

· L 28 % 20-40%

· M 6.5% 2-8%

· E 2% 1-4%

· B 0.5 % .5 - 1%

Diagnosis:
Patient: Jenny (30 year old, female)
CBC Patient Value Normal Range
Jenny has been having breathing difficulties and a
runny nose ever since she moved to southern Illinois. RBCs 4.3 million/uL 3.5-5.5 million/uL
Examination reveals normal blood pressure and heart
rate, with a note that patient has watery eyes. · Hb 14.5 g/dL 13 - 18 g/dL

· HCT 49 % 45% to 52%

PLTs 260 K/uL 150-400 K/uL

WBCs 6.5 K/uL 4.5-11 K/uL

· N 50 % 40-69%

· L 38 % 20-40%

· M 5% 2-8%

· E 6.4 % 1-4%

· B 0.6 % .5 - 1%

Diagnosis: