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    mmmartinez1583
    Rytary contains carbidopa and levodopa which prevents levodopa from converting to dopamine outside the brain to minimize side effects like nausea. The starting dose is 23.75/95 mg three times daily for 3 days then increased to 36.25/145 mg three times daily. Contraindications include angle-closure glaucoma and malignant melanoma. Nursing interventions include monitoring for therapeutic effects and side effects.

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    Drug

    Uploaded by

    mmmartinez1583
    8 views2 pages
    Rytary contains carbidopa and levodopa which prevents levodopa from converting to dopamine outside the brain to minimize side effects like nausea. The starting dose is 23.75/95 mg three times daily for 3 days then increased to 36.25/145 mg three times daily. Contraindications include angle-closure glaucoma and malignant melanoma. Nursing interventions include monitoring for therapeutic effects and side effects.

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    Rytary contains carbidopa and levodopa which prevents levodopa from converting to dopamine outside the brain to minimize side effects like nausea. The starting dose is 23.75/95 mg three times daily for 3 days then increased to 36.25/145 mg three times daily. Contraindications include angle-closure glaucoma and malignant melanoma. Nursing interventions include monitoring for therapeutic effects and side effects.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    8 views2 pages

    Drug

    Uploaded by

    mmmartinez1583
    Rytary contains carbidopa and levodopa which prevents levodopa from converting to dopamine outside the brain to minimize side effects like nausea. The starting dose is 23.75/95 mg three times daily for 3 days then increased to 36.25/145 mg three times daily. Contraindications include angle-closure glaucoma and malignant melanoma. Nursing interventions include monitoring for therapeutic effects and side effects.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
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    RYTARY (carbidopa & levodopa) Enzyme-inhibitor, agonist

    It keeps levodopa from being prematurely turned outside of the brain to dopamine. This
    minimizes or avoids negative consequences like nausea.

    MECHANISM OF ACTION
    Levodopa enters the brain through a variety of pathways and is converted to dopamine by
    decarboxylation. Due to a drop in natural concentrations, this additional dopamine stimulates
    dopaminergic receptors to fill the function that endogenous dopamine cannot.

    DOSAGE FOR RYTRY


    The recommended starting dosage of Rytary is 23.75 mg/95 mg taken orally three times a day
    for the first 3 days. On the fourth day of treatment, the dosage of Rytary may be increased to
    36.25 mg/145 mg taken three times a day.

    CONTRAINDICATIONS
    Angle-closure glaucoma, malignant melanoma

    NURSING INTERVENTIONS
     Assess therapeutic response.
     observe for the development of suicidal tendencies.
     Monitoring for side-effects, including mental state assessment and blood pressure
    measurement.
     Give with meals if GI upset occurs.
     Ensure that patient voids before receiving dose if urinary retention is a problem.
     Monitor hepatic, renal, hematopoietic, and CV function.
     For patients who take multivitamins provide Larobec, a preparation without pyridoxine.
    benztropine (Cogentin) Anticholinergics ANTIPSYCHOTIC
    It is used for drug-induced extrapyramidal symptoms, prevention of dystonic reactions, and
    treatment of acute dystonic reactions.

    MECHANISM OF ACTION
    Acetylcholine and histamine receptors are antagonistic to benzotropine. Benztropine works in
    the central nervous system and smooth muscles by competing with acetylcholine for muscarinic
    receptors. As a result, it inhibits muscarinic receptors, which decreases central cholinergic
    actions and seems to alleviate Parkinson disease symptoms.

    DOSAGE
    Cogentin usual adult dose ranges from 0.5 - 6 mg/day in 1-2 divided doses.

    CONTRAINDICATIONS
    Generally, benztropine is contraindicated if the patient has a history of hypersensitivity to
    benztropine mesylate or any component of the drug formulation. Also, benztropine is
    contraindicated in patients with the following specific syndromes and diseases: Urinary
    Retention, Bladder Obstruction, and Prostatic Hypertrophy, Tachycardia, Tardive Dyskinesia,
    Behavioral and Psychological Changes, Myasthenia Gravis and Autonomic Neuropathy,
    Alcoholism and Hyperthermia, Contact Lenses

    NURSING INTERVENTIONS
     Assess therapeutic effectiveness.
     Monitor I&O ratio and pattern. Advise patient to report difficulty in urination or infrequent
    voiding. Dosage reduction may be indicated.
     Closely monitor for appearance of S&S of onset of paralytic ileus including intermittent
    constipation, abdominal pain, diminution of bowel sounds on auscultation, and
    distention.
     Monitor for and report muscle weakness or inability to move certain muscle groups.
    Dosage reduction may be needed.
     Supervise ambulation and use bed side rails as necessary.
     Report immediately S&S of CNS depression or stimulation. These usually require
    interruption of drug therapy.

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