T-Level Booklet
T-Level Booklet
T-Level Booklet
GCMS-QP2010 SE System 10
Engineering Solutions 14
e-Learning Resources 17
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Pharmaceuticals
Shimadzu’s Commitment
to Furthering Education
Our team of industry experts and skilled application scientists with over
100 years combined experience are ready to work with you, tailored to
your requirements and aspirations.
Environmental
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Uses of Chromatography in Everyday Life
Chromatography may not be the most well know scientific field but is steeped in history. Decades
of scientific advances led us to today’s uses of chromatography. Uses that include industry sectors
such as forensic science, pharmaceutical, chemical, food and healthcare. Chromatography allows all
these industries and more to separate each component within a mixture to accurately identify and
quantitate the amounts within varying types of samples.
Forensic testing
Crime dramas such as CSI have brought criminal investigations to mainstream television. You may have heard of
Major Mass Spec in NCIS; this Shimadzu gas chromatography mass spectrometer is not only used on this drama
series but also in reality. Crime scene samples can all be processed for various compounds, including analysis of
chemicals within arson cases, soil analysis from shoes or carpet, or identification of unknown particles found
on clothing. These tests can also be used during post mortems to determine conditions such as heart attacks or
perhaps drug overdose that may have caused death.
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Biological sample analysis
Due to the precision with which chromatography can identify substances
in blood and urine, it is widely used not only within hospitals, but also by
the police and authorities such as the World Anti-Doping Agency (WADA).
No matter if you are having a routine blood test for health reasons, being
investigated for taking illegal drugs or an athlete being checked for banned
substances, the same chromatography principles are utilised.
Food analysis
Have you ever wondered how manufacturers maintain the quality and
consistency of their products? Continuous monitoring of levels of sugar going
into final products or alcohol content in spirits are basic chromatography
tests. Chromatography can even determine how “bitter” your beer will taste.
However, it can also detect the substances that should not be there! News
stories have reported the scandal where horse meat replaced beef in processed
foods, high heavy metal levels in rice and melamine, a carcinogen within baby
milk formula in China. It can also show you what colourants are used in your
food and drink – even blue smarties!
Household products
Have you ever picked up a face cream, shampoo or kitchen cleaner and read
the ingredients? All these ingredients are individually tested for a variety of
reasons. This also includes products we store in sheds and garages. Pesticides,
herbicides and insecticides are all tested for their environmental impact and
efficacy of their active ingredient, to ensure that product simply does the job
effectively and is not dangerous to us or the environment.
Pharmaceutical
2020 saw the start of a worldwide pandemic and development of new
vaccinations. Chromatography was used to not only analyse COVID-19
detection test components, but also run vigorous testing on vaccinations. As
well as the vaccines, there were many other medications tested in hope to
reduce symptoms. Chromatography has led the way in testing and developing
new drugs and vaccinations for decades. Who knows what chromatography
will help discover next?
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Analytical Teaching Lab
Instrument Portfolio
Liquid Chromatography
Gas Chromatography
UV-Vis Spectrophotometer
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i-Series HPLC System
• Easy to use
• Modern touchpad visual display
• High sample capacity
• Common software platform
Laboratory experiments
mAU
500 Cannabinoid testing
400 CBDA CBGA
100
THCV
∆9-THC ∆8-THC
interest in recent years. There are many variants of cannabinoids with similar
0
0.5 1 1.5 2 2.5 3 min
structures, making them difficult to analyse. However, modern analytical
techniques can differentiate these compounds and identify each moiety.
Using this package students can analyse various samples, similar to the U.K.
Food Standards Agency (FSA), to confirm the stated concentration as well as
check for the legality of the samples.
mAU
300
Paracetamol
Pharmaceutical drug testing
200 Caffeine
100
Acetylsalicylic acid The pharmaceutical industry has to ensure that their drugs, vaccines, and
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0.5 1 1.5 2 2.5 3 min ointments have not only the correct active ingredients but also at the correct
dosage level. HPLC is “the gold standard” for analysing the concentration of
the active compounds within the pharmaceutical industry. In this package,
students will learn to interpret and draw conclusions from chromatograms
from standards and over-the-counter drugs, such as aspirin, paracetamol or
caffeine. Utilising calibration curves to cover a wide range of concentrations
students can answer the questions of: Which compounds are present and
quantify how much? Do the amounts match the stated concentrations?
products are safe for the consumer. Typical tests within the beverage
0.5 1 1.5 2 2.5 3 min
mAU
300
Energy Drink
200
industry are sugar or caffeine analysis. These simple tests on widely available
100
0
products show students both sample pre-treatment and testing for common
0.5 1 1.5 2 2.5 3 min
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GC-2010 Pro Academic Teaching Lab System
The GC-2010 Pro has been designed with academic and teaching
facilities in mind. The new GC system comes fitted with a host of
features geared towards ease of use, flexibility, and long-term
robustness. These include:
Laboratory experiments
Solvent impurities
Application involves the analysis of various laboratory solvent mixes, and
comparison to commercially available spirits from hardware stores. Analysts learns
to separate solvents on different phase columns and develop knowledge on
boiling point versus polarity separation. Exercise teaches method setup and basic
GC maintenance.
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GCMS-QP2010 SE System
Laboratory experiments
Fragrance analysis
Application on GCMS looking at the various fragrance chemicals used in perfumes
and personal care products. Analysis focuses on organic aromatic compounds,
and the various “smells” they contribute to commercial products. Exercise teaches
library searching and spectral breakdown in basic Mass Spectrometry.
Caffeine detection
Exercise focuses on human testing for drugs, but using a legal and easily available
component. Caffeine analysis in urine (or synthetic serum). Exercise uses GCMS to
identify caffeine in a difficult matrix and the preparation of analytical standards to
provide accurate quantification in a human sample.
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UV-1900i UV-Vis Spectrophotometer
Laboratory experiments
The experiment requires accuracy in creating the standards and precision when
making the extractions and will show the relative caffeine content of beverages.
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IRSpirit - FTIR Spectrophotometer
Laboratory experiments
Identification of microplastics
Plastics should be collected from the environment. The plastics can be large
samples or very small amounts recovered from soil or (for instance) the fluff from
tumble-drier filters. These should be separated by visually identified type and
then transferred to the ATR crystal. Even tiny flakes of plastics which are more
than approx. 100-micron microspheres can be placed individually on the ATR, the
spectrum determined, and then the plastic identified by comparison to the library
files, or from first principles by establishing the bonds present.
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Engineering Solutions
Shimadzu offers a range of materials testing instrumentation to suit academic requirements. The EZ
Test is a compact solution for performing a wide variety of tests up to a maximum of 5kN, while the
AGS-X table top universal testing machines series offers practical testing solutions for a variety of
tests requiring force of up to 50kN.
Shimadzu’s material testing solutions are supported by Trapezium X operating software allowing for user friendly
programming and set up. Safety features are at the core of our machine development, with multiple levels of safety
triggers built into both the machine and software.
The system uses a high-precision load cell that guarantees accuracy to within
±0.5% of the indicated value (high-precision type) over a wide range from 1/500
to 1/1 of the rated capacity.
This helps ensure highly reliable evaluation tests over a wide range of loads.
AGS-X:
✔ Real-time auto tuning of control parameters
✔ Easy comparisons to unknown samples without the need for preliminary tests
✔ Quick stress control test to an ISO 6892-2009
✔ Achieve an accurate S-S curve with high-precision load cells
FROM
1msec
±0.5 1/500
(1000Hz)
TO 1/1
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Materials Testing Experiments
These calculations allow you to choose materials that do not bend when
supporting the loads you require for your application.
The test uses an EZ-Test universal testing machine and a three-point bend fixture
to bend plastic test bars to acquire the data needed to make the calculations.
Peel test
A Shimadzu material testing system is ideal for measuring the peel, tear,
and friction properties of elastomers, adhesives, glues, cements, laminates,
packaging, fabrics, coatings, labels, tapes, medical devices, and other products,
materials, and components.
With the Shimadzu UTM, you can accurately calculate average peel strength load
over a specified distance and strength per unit width of adhesive. All adhesive
testing systems feature constant-rate-of-extension (CRE) and constant-rate-of-
load (CRL) control which allows you to perform a wide variety of adhesive tests
with only one testing machine.
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e-Learning Resources
All college students and personnel will gain access to Shimadzu e-learning resources.
The resources are geared towards students and young scientist. These cover the theory and key
principles of chromatography and mass spectrometry techniques.
There are numerous e-learning videos available including such topics as:
Gas Chromatography –
Introduction to GCMS
Mass Spectrometry (GCMS)
• Introduction to GCMS
• Single Quadrupole (SQ) vs Triple Quadrupole
(TQ) GCMS
• GCMS operation and maintenance
• Introduction to GCMS method development
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Chromatogram 10
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2.5 5.0 min
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Maintenance, Service and On-going Support
Shimadzu UK is dedicated to providing the best possible service to enable our customers to make the
most of their equipment. With our team of Factory Trained & Certified Field Service Engineers and
Product Applications Specialists, we are easily accessible to support and answer any questions that
might arise.
Maintenance and support of analytical instrumentation is a vital part of laboratory operation. For our customer’s
peace of mind, Shimadzu instrumentation is supplied with 12 months warranty, commencing on the installation of the
equipment.
In addition, we offer an academic maintenance plan, specifically developed to meet the needs of teaching laboratories.
This plan includes an annual preventive maintenance visit to keep instrumentation running smoothly, as well as a 35%
discount on emergency labour and travel charges.
The training sessions tailored to end user’s needs and requirements will also be provided as a part of the package. In
addition, we pride ourselves on providing continuous technical support for the lifetime of the instrument at no extra
cost. Our customers have full online access to the Shimadzu online support portal and direct contact details of your key
technical specialist.
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Additional Value Offerings
In line with Shimadzu’s ethos of Excellence in Science, we highly value the importance of investing in
the next generation of talent. The students of today will be the driving force for the future of science
and technological advances.
As part of the purchase of new analytical instrumentation, Shimadzu’s proposal extends to the
following areas:
• Supporting the implementation of the new teaching laboratory with the latest
instrumentation at a collaborative subsidised rate
• Shimadzu to create and promote an interview with the college staff focusing on
science teaching portfolio
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Shimadzu UK Limited
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Sales Hotline: 01908 552209, Service Hotline: 01908 552202, Accounts: 01908 552201
Facsimile: 01908 552211, UK Registration No. 5342169 Web: www.shimadzu.co.uk
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