Scribd Logo
Upload

Welcome to Scribd!

  • 2K views

    Medicinal-Chemistry Mcqs 1

    Uploaded by

    Abera Lemma
    This document contains 25 multiple choice questions about the history and development of medicinal chemistry. It covers topics like the introduction of aspirin, the synthesis of epinephrine, phases of clinical drug trials, and concepts in drug discovery such as hits and leads. The questions test knowledge of important dates, terms, procedures and structures in the field of medicinal chemistry.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Medicinal-Chemistry Mcqs 1

    Uploaded by

    Abera Lemma
    2K views5 pages
    This document contains 25 multiple choice questions about the history and development of medicinal chemistry. It covers topics like the introduction of aspirin, the synthesis of epinephrine, phases of clinical drug trials, and concepts in drug discovery such as hits and leads. The questions test knowledge of important dates, terms, procedures and structures in the field of medicinal chemistry.

    Original Title

    medicinal-chemistry mcqs 1

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    This document contains 25 multiple choice questions about the history and development of medicinal chemistry. It covers topics like the introduction of aspirin, the synthesis of epinephrine, phases of clinical drug trials, and concepts in drug discovery such as hits and leads. The questions test knowledge of important dates, terms, procedures and structures in the field of medicinal chemistry.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    2K views5 pages

    Medicinal-Chemistry Mcqs 1

    Uploaded by

    Abera Lemma
    This document contains 25 multiple choice questions about the history and development of medicinal chemistry. It covers topics like the introduction of aspirin, the synthesis of epinephrine, phases of clinical drug trials, and concepts in drug discovery such as hits and leads. The questions test knowledge of important dates, terms, procedures and structures in the field of medicinal chemistry.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    You are on page 1of 5

    Medicinal Chemistry 1 MCQs [set-1]

    Chapter: Introduction, History and development of Medicinal Chemistry

    1. Aspirin is introduced by_________in 1889


    A. Dreser's
    B. Emil Fischer and Mering
    C. Barger and Dale
    D. None of above
    Answer: A

    2. First hormone epinephrine was synthesized in Year


    A. 1903
    o m
    B. 1904
    . c
    C. 1909
    te
    D. 1889
    a
    Answer: B

    q M
    c
    3. Who is founder of modem medicine?
    A. Hippocartes M
    B. Clark
    C. Charak
    D. Henry's
    Answer: A

    4. Identification of a new chemical entity as a potential therapeutic agent (From


    Hit to Lead) is known as
    A. Drug discovery
    B. Drug development
    C. Both of above
    D. None of above
    Answer: A

    5. The process of bringing a new pharmaceutical drug to the market once the lead
    compound has been identified through the process of drug discovery. (From Lead
    to NDA) is known as
    A. Drug discovery
    B. Drug development
    C. Both of above
    D. None of above
    Answer: B

    6. Natural products or derivatives or synthetic substances with good binding ability


    in Drug discovery is known as
    A. Hit
    B. Lead
    C. NDA
    D. IND
    Answer: A

    7. Compound with good activity and selectivity in screening during drug discovery
    is known as
    A. Hit
    B. Lead
    C. NDA
    D. IND
    Answer: B

    8. The main goals of pre-clinical studies


    A. To determine the safe dose for first-in-man study
    B. To assess a product's safety profile
    C. A and B both
    D. None
    Answer: C

    9. IND stands for


    A. Improved new drug
    B. Investigational new drug
    C. International new drug
    D. International novel drug
    Answer: B

    View all MCQ's at McqMate.com


    10. Human micro dosing studies conducted in which clinical phase ?
    A. Phase 0
    B. Phase I
    C. Phase II
    D. Phase III
    Answer: A

    11. MTD is
    A. Maximum targeted dose
    B. Minimum tolerated dose
    C. Minimum targeted dose
    D. Maximum tolerated dose
    Answer: D

    12. Single ascending dose studies are done in_____


    A. Phase lb
    B. Phase Ia
    C. Phase II
    D. Phase Ila
    Answer: B

    13. NDA is
    A. New Drug Application
    B. New Drug approval
    C. Noval Drug Admistration
    D. New Drug agenda
    Answer: A

    14. Phase IV trial is also known


    A. Base of clinical trial
    B. Multiple ascending dose era
    C. Post marketing Surveillance
    D. Pre-clinical trial
    Answer: C

    15. How many people will be selected for phase I trial?


    A. The whole market will be under surveillance

    View all MCQ's at McqMate.com


    B. 300-3000 people
    C. 20-300 people
    D. 20-50 people
    Answer: D

    16. How many people will be selected for phase II trial?


    A. The whole market will be under surveillance
    B. 300-3000 people
    C. 20-300 people
    D. 20-50 people
    Answer: C

    17. How many people will be selected for phase III trial?
    A. The whole market will be under surveillance
    B. 300-3000 people
    C. 20-300 people
    D. 20-50 people
    Answer: B

    18. Which one of the following will be checked under phase IV surveillance?
    A. The whole market will be under surveillance
    B. 300-3000 people
    C. 20-300 people
    D. 20-50 people
    Answer: A

    19. Precision Medicine is an emerging approach depending on


    A. Genomic study of individual
    B. Diagnostic process of individual
    C. Diseases conditions
    D. None of above
    Answer: A

    20. How many main families of GPCRs are there?


    A. 5
    B. 6
    C. 7

    View all MCQ's at McqMate.com


    D. 4
    Answer: B

    21. Which of the following reactions is catalyzed by the enzyme adenylate cyclase?
    A. Conversion of ATP to cyclic AMP
    B. Conversion of cyclic AMP to AMP
    C. Conversion of cyclic AMP to ATP
    D. Conversion of AMP to cyclic AMP
    Answer: A

    22. Oxadiazole ring contains


    A. 1 Nitrogen /Oxygen
    B. 2 Oxygen/ Nitrogen
    C. 2 Nitrogen/Sulphur
    D. 2 Nitrogen/Oxygen
    Answer: D

    23. The hetroaromatic redical is called


    A. Anthryl
    B. Naphthyl
    C. Phenanthryl
    D. Dibenzyl
    Answer: B

    24. Name of this aromatic ring is


    A. Diphenylmethyl ethane
    B. 2-ethyl-1-methyl naphthalene
    C. 1-ethyl-2-methyl naphthalene
    D. 1-ethyl-1-methyl naphthalene
    Answer: C

    25. Name of this aromatic ring is


    A. Azopane
    B. Azepine
    C. Azepane
    D. None of above
    Answer: C

    View all MCQ's at McqMate.com

    You might also like