Republic of the Philippines

Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ

Quarter 3 Division Assessment in General Biology 2 (Grade 12)

SY 2022-2023

DIRECTIONS: Read and analyze each item carefully. Choose the letter of the best
answer.

1. Who is the Father of Genetics?

A. Aristotle C. Charles Darwin
B. Carolus Linnaeus D. Gregor Mendel

2. Which of the following branches of Biology deals with the study of how traits are passed
from parent to offspring?
A. Embryology C. Genetics
B. Evolution D. Systematics

3. Which of the following is NOT used to predict the possible gene makeup of offspring?
A. Fork Method C. Probability
B. Pascal’s Triangle D. Punnett Square

4. What will be the possible genotypes of a cross between homozygous dominant and
heterozygous yellow flower?
A. YY, Yy C. Yy, Yy
B. Yy, yy D. YY, yy

5. What is the probability of obtaining 4 males (a) and 8 females (b) from a hen who will
hatch 12 eggs?
A. 12.0 % C. 12.3 %
B. 12.1 % D. 13.0 %

6. What is the total number of possible gametes of the genotype AaBbCcddEe?

A. 12 C. 16
B. 14 D. 18

7. In rabbits, black coat (B) is dominant over brown (b) and straight hair (H) is dominant to
curly (h). Which of the following could be possible phenotypes of a cross between two
hybrid rabbits?
I. Black and straight III. Brown and straight
II. Black and curly IV. Brown and curly

A. I and II only C. III and II only

B. III and IV only D. All of the above

8. Which of the following alleles show up in males whether dominant or recessive?

A. X – linked C. Y – linked
B. B. X – limited D. Y – limited

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
9. What refers to a graphic representation of how a trait is passed from parents to offspring?
A. Family tree C. Pedigree
B. Fork Method D. Punnett Square

10.Which of the following types of inheritance explains the blending of traits?

A. Codominance C. Multiple Alleles
B. Incomplete Dominance D. Sex-Linked Genes

11.In some flowers, having red flowers (R) is incompletely dominant over yellow flowers (r).
What will be the phenotype of a hybrid individual?
A. Red flowers C. Orange flowers
B. Red and yellow flowers D. Yellow flowers

12.A person with alleles for blood types A and O marries someone with alleles for blood type
AB. Which of the following blood types is NOT possible for the offspring to have?
I. type A III. type AB
II. type B IV. type O
A. I C. III
B. II D. IV

13.Red hair and white hair are codominant in cattle. Heterozygous (HRHW) cattle have red
hairs and white hairs, they are called roan. What will be the genotypic ratio of the
offspring of a roan bull and a red haired cow?
A. 1:1 C. 9:3:3:1
B. 1:1:1:1 D. 1:1:2:2:4:2:2:1:1

14.Which of the following is NOT a nitrogenous base found in ribonucleic acid (RNA)?
A. Adenine C. Guanine
B. Cytosine D. Thymine

15.Which scientists deduced that deoxyribonucleic acid (DNA) has a double helix structure?
A. Hooke and Leeuwenhoek C. Schleiden and Schwann
B. Linnaeus and Mendel D. Watson and Crick

16.Which of the following is a double-stranded, self-replicating, circular DNA molecule

present in bacteria which is widely used as a gene cloning vector?
A. Cosmid C. Phagemid
B. Genome D. Plasmid

17.What refers to the process of producing polypeptide chains (proteins) from mRNA?
A. Recombination C. Transcription
B. Replication D. Translation

18.Which of the following are enzymes is involved in genetic engineering?

A. Reaction Enzyme C. Recombinant Enzyme
B. Ready Enzyme D. Restriction Enzyme

19.Which of the following is an example of genetic engineering?

Loyal, Excellent, Accountable and Dedicated to Service
Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
A. Cross pollination of squash flowers
B. The insertion of cloned genes to plant cells
C. The use of bacteria in order to produce human insulin
D. A farmer chooses a breed of cow for of greater milk production

20.Which of the following statements regarding the steps of DNA replication is most
accurate?
A. Unwinding is the first step in DNA replication, and is catalyzed by primase
enzymes.
B. Priming is essential for the initiation of DNA replication, and is catalyzed by
primase enzymes.
C. The main function of DNA polymerases during replication is to unwind the
double helix structure of DNA.
D. Proofreading occurs after termination, and involves repairing errors in the newly
synthesized DNA strand.

21.Bacterial cells as host organisms may express the gene to make protein products such as
insulin and growth hormones. Which of the following processes are involved?
A. Replication and Transcription
B. Transcription and Translation
C. Replication and Transformation
D. Transcription and Transformation

22.What refers to the manipulation, introduction and expression of specific genes or DNA in
target organisms?
A. Genetic drifting C. Genetic manipulation
B. Genetic engineering D. Genetic mutation

23.Which of the following sequences presents the correct order of the Recombinant DNA
technology process?
A. Getting bacterial plasmid → Inserting human gene in bacterial plasmid →
Cutting of bacterial plasmid → Inserting plasmid in new bacterium → Cell
division of engineered bacterium
B. Getting bacterial plasmid → Cutting of bacterial plasmid → Inserting plasmid in
new bacterium → Inserting human gene in bacterial plasmid → Cell division of
engineered bacterium
C. Getting bacterial plasmid → Cutting of bacterial plasmid → Inserting human
gene in bacterial plasmid → Inserting plasmid in new bacterium → Cell division
of engineered bacterium
D. Getting bacterial plasmid → Inserting human gene in bacterial plasmid →
Inserting plasmid in new bacterium → Cutting of bacterial plasmid → Cell
division of engineered bacterium

24.What refers to the form of artificial DNA that is created by combining two or more
sequences from two different species?
A. Cloned DNA C. Rearranged DNA
B. Mutant DNA D. Recombinant DNA

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
25.Recombinant DNA is an example of modern biotechnology, which of the following is NOT
an application of biotechnology?
A. Arts C. Forensics
B. Food production D. Medicine
26.Which of the following statements is NOT a use or application of recombinant DNA and
biotechnology?
A. To change microbes for aesthetics.
B. To diagnose, treat or cure diseases.
C. To obtain better farm and domestic animals and fish.
D. To make plants easier and less expensive to cultivate.

27.Which of the following is a record of the life forms and geological events in Earth’s history?
A. Biological Time Scale C. Geographical Time Scale
B. Evolutional Time Scale D. Geological time Scale

28.Which of the following events happen at the end of the Paleozoic?

A. Phyletic gradualism
B. Punctuated equilibrium
C. Largest mass extinction
D. Evolutionary change between species

29.What is the Cenozoic Era known for?

A. Age of Fishes C. Age of Reptiles
B. Age of Mammals D. Age of Trilobites

30.Which of the following is NOT a period in Mesozoic Era?

A. Carboniferous C. Jurassic
B. Cretaceous D. Triassic

31.Which of the following organisms appeared during the Mesozoic Era?

I. Mammals III. Conifers
II. Reptiles IV. Fishes

A. I and II C. III and IV

B. II and III D. I, II and III
32.Mechanisms of evolution gave rise to changes in population including genetic variation,
which of the following is NOT a mechanism that affects a change in population causing
evolution?
A. Gene Flow C. Natural Selection
B. Genetic selection D. Non-random mating

33.Which of the following is NOT an example of a genetic drift situation?

A. Artificial selection C. Population bottleneck
B. Founder effect D. None of the above (Genetic selection)

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
34.What causes the failing of DNA to copy accurately or by external influences such as
chemicals and radiation?
A. Gene Flow C. Mutation
B. Genetic drift D. Natural Selection

35.Which of the following statements are CORRECT?

I. Natural selection is “survival of the fittest”.
II. Natural selection involves non-random mating.
III. Natural selection can be affected by gene flow.
IV. Natural selection allows you to choose which organisms survive.

A. I, II and III C. I, III and IV

B. II, III and IV D. I, II and IV

36.Which of the following is NOT a theory of Evolution?

A. Theory of Use and Disuse
B. Theory of Natural Selection
C. Theory of Artificial Selection
D. Theory of Acquired Characteristics

37.Which of the following best describes the contribution of Charles Darwin to the
development of evolutionary thought?
A. He discovered the laws of inheritance.
B. He developed the concept of genetic drift.
C. He developed the theory of natural selection.
D. He proposed that acquired traits could be passed on to offspring.

38.What refers to the type of fossils where hard parts of plants or animals are replaced by
minerals over time?
A. Carbon films C. Preserved remains
B. Petrified fossils D. Trace fossils

39.Which of the following pieces of evidence supports that all living organisms on Earth
share a common ancestor?
A. The occurrence of convergent evolution.
B. The occurrence of horizontal gene transfer.
C. The presence of homologous structures in different species.
D. The observation of analogous structures in different species.

40.The study of evidences of evolution helps prove the occurrence of change in population
along time, which of the following statements about evidences of evolution is
INCORRECT?
A. Similar embryos show common ancestry.
B. Analogous structures do not show common ancestry.
C. Homologous structures are evidence of a common ancestor.
D. Populations cannot show variation from one place to another.

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
41.What is the evidence of evolution that demonstrates that two closely-related organisms
will have similar DNA, RNA, and protein (amino acid) sequences?
A. Embryology C. Geographic distribution
B. Comparative anatomy D. Molecular and genetic

42.Based on homologous and analogous structures, which two organisms are most likely
related to each other?
A. Human and cat C. Fly and bat
B. Whale and gold fish D. Butterfly and humming bird
For question number 43, refer to the situation below.

A group of researchers is studying the evolutionary relationships between

different species of primates. They analyzed several primates' DNA, RNA, and
protein sequences and looked at their anatomical structures. Based on their
findings, they came up with the following data:
 Species A and B have very similar DNA, RNA, and protein sequences, and they
have very similar anatomical structures.
 Species B and C have slightly different DNA, RNA, and protein sequences, and
they have slightly different anatomical structures.
 Species A and C have very different DNA, RNA, and protein sequences, and
they have very different anatomical structures.

43. Based on this data, which of the following statements is most likely TRUE?
A. Species A, B, and C are equally related to each other.
B. Species A and B are more closely related to each other than species C.
C. Species B and C are more closely related to each other than species A.
D. It is not possible to determine the evolutionary relationships between these
species based on this data.

44.What refers to the field of biology dealing with diversity and evolutionary history of life?
A. Embryology C. Genetics
B. Evolution D. Systematics

45.Which of the following is the most important factor in determining the phylogenetic
relationship between two species?
A. Geographic location and distribution
B. Reproductive compatibility and hybridization
C. Shared ancestral traits and evolutionary history
D. Physical appearance and morphological characteristics

46.What do you call a group of organisms at a particular level in a classification system?

A. Family C. Kingdom
B. Genus D. Taxa

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]
 Republic of the Philippines
Department of Education
REGION III- CENTRAL LUZON
SCHOOLS DIVISION OFFICE - SCIENCE CITY OF MUÑOZ
47.Who is the scientist that worked in the nomenclature and classification of organisms and
designed our hierarchical classification scheme?
A. Aristotle C. Charles Darwin
B. Carolus Linnaeus D. Gregor Mendel

48.Which of the following sequences presents the correct order of the taxonomic hierarchical
classification scheme?
A. Kingdom → Phylum → Class → Order → Family → Genus → Species
B. Kingdom → Phylum → Order → Family → Class → Genus → Species
C. Kingdom → Family → Phylum → Class → Order → Genus → Species
D. Kingdom → Phylum → Class → Order → Family → Species → Genus

49.Phylogenies are inferred by identifying organismal features (characters) that vary among
species. Which of the following is NOT a character basis for phylogeny?
A. Behavioral C. Molecular
B. Economical D. Morphological

50.What refers to the shared characters that result from common ancestry?
A. Analogy C. Homologous
B. Convergence D. Homoplasy

Loyal, Excellent, Accountable and Dedicated to Service

Address: Brgy. Rizal, Science City of Muñoz, 3119
Telephone No.: (044) 806 -2192; Email Address: [email protected]