Liquid Preparations B. Advantages Disadvantages C. Handling and Storage 1.aqueous Solutions

Download as doc, pdf, or txt
Download as doc, pdf, or txt
You are on page 1of 3

Liquid B. Advantages Disadvantages C.

Handling and Storage


Preparations
1.Aqueous
Solutions
-Aromatic Water -Free from empyreumatic -salting out of certain -protect from intense light and
and other foreign odors. ingredients such as very excessive heat
-used as soluble salts -stored in light-resistant and airtight
perfumed/flavored -deterioration with time thus containers.
vehicles it should be made in small
quantities
-Aqueous Acids -important in -possess incompatibilities of
pharmaceutical the anions they contain.
manufacturing analysis. -may irritate the mucous
membrane of the mouth and
attack the enamel of the
teeth.
-Solutions
-Douches - It is directed to the -should be diluted or dissolved in the
appropriate body part by appropriate amount of warm water
bulb syringes. prior to use.
-functions as a cleansing
and antiseptic agent.
-Enemas -Employed to evacuate
the bowel, influence the
general system by
absorption or affect a
local disease.
-Gargles -Treats the pharynx and -must be diluted with water prior to
nasopharynxby forcing air use
from the lungs through
the gargle that is held in
the throat.
-Mouthwashes -has therapeutic and
cosmetic use
-reduce plaque, gingivitis,
dental caries and
stomatitis; reduce bad
breath.
-Nasal Solutions -the nasal tissue is highly -keep packages tightly closed during
vascularized making it an period of nonuse.
attractive site for rapid
and efficient systemic
absorption
-Otic Solutions -remove excessive -dispensed in a container that permits
cerumen or earwax; tx of the administration of drops.
ear infections.
-Irrigation -used to wash or bathe -packaged in single-dose containers
Solutions surgical incisions, preferably Type I or Type II glass, or
wounds, or body tissues. suitable plastic containers and then
sterilized.
2.Sweet Viscid
Solution
-Syrups -possess remarkable -cause an increase dental -preserved in well-dried bottles,
taste-masking properties caries and gingivitis. preferably those that have been
for bitter or saline drugs sterilized; these bottles should not
hold more than is likely to be required
during 4-6 weeks and should be filled
completely, carefully closed and
stored in a cool dark place
-Honeys
-Mucilages -prone to decomposition,
showing appreciable
viscosity on storage; difficult
to prepare
-Jellies -used as lubricants for -prone to microbial
surgical gloves, catheters contamination
and rectal thermometers
3. Non-
aqueous
Solutions
-Elixirs -more readily prepared -because it contains alcohol,
and manufactured than it has some incompatibilities
syrups
-Glycerins -valuable pharmaceutical -hygroscopic and should be stored in
solvent tightly closed containers
- -designed so that the -the drug is prepared in sealed glass
Inhalations/inhal drug is carried into the vials that are covered with protective
ants respiratory tree. gauze cloth.
-effects of the drug are -container should be tightly closed
rapid after each opening to prevent loss of
drug vapors.
-Liniments -should be marked with “For External
Use Only”
-Spirits -should be stored in tight, light-
resistant containers and in a cool
place.

Liquid B. Advantages Disadvantages C. Handling and Storage


Preparations
4. Medicated -contains some added -stored at room temperature
Solutions medicinal substance

Solid Dosage
Forms
1.Tablets -advantages to the -creeping: concentration of -an effervescent tablet requires a
manufacturer: the medication on the barrier to moisture
(simplicity and economy surface of the tablet caused
of preparation, stability by capillarity and rapid
and convenience in evaporation of the solvent
packaging, shipping and from the surface.
dispensing)
-advantages to the
patient
(accuracy of dosage,
compactness, portability,
blandness of taste and
ease of administration)
2.Capsules -flexible: permits a choice -if stored in high humidity -packed with desiccant materials
in prescribing a single environment, capsule shells
drug or a combination of may soften, stick together
drugs at the exact dosage and become distorted and
level lose their shape.
-some patients find it -in the environment of
easier to swallow extreme dryness, gelatin
capsules than tablets capsules may harden and
crack under slight pressure
3.Powders -flexibility in -time-consuming to prepare
(Paper Tabs) compounding and and are not well-suited for
relatively good chemical dispensing the many
stability unpleasant tasting,
hygroscopic, or deliquescent
drugs.
Semi-solids
1.Creams
2.Ointments -emollient -stability problem: Bleeding- “
mineral oil separate at the
top of an ointment
-slight changes in
temperature can affect the
consistency of the ointment
greatly
3.Milk and -suspending agent for “Shake well” label and “Avoid
Magmas insoluble substances freezing”
4.Lotions -applied to unbroken skin
without friction
-provides moisture to the
skin
5.Suppositories -best stored in a cool place,
Theobroma cacao should be
refrigerated.
-Glycerin and glycerinated gelatin
suppositories are often packaged in
tightly closed screwcapped glass
containers

You might also like